Molecular aggression: variation and heritability of the levels of reactive oxygen species, and their effects on the evolution of life histories in the wild

分子攻击：活性氧水平的变异和遗传性及其对野生生命史进化的影响

• 批准号: DP0881329
• 负责人: Prof Mats Olsson
• 金额: $ 23.74万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2015-06-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0881329
• 关键词: Molecular; aggression; variation; heritability; levels

Three areas of biology have intrigued every generation since Aristotle (c. 300 BC)- sex, embryology, and ageing. This proposal targets all three of these areas with a special focus on aspects of ageing. In particular, we assess how 'free radicals', so often identified in our food and wine for good and bad, exert selection on living organisms and whether resistance (and defense) towards free radicals may drive evolution of ageing in the wild, its trade offs with fertility and fecundity, and how it is influenced by sexual or non-sexual reproduction. In spite of excellent work in the laboratory, this is the first attempt to do this in 'the real world' and will extend Australia's excellent reputation in evolutionary biology.

生物学的三个领域吸引了自亚里士多德以来的每一代人。公元前300年）-性别，胚胎学和衰老。这项建议针对所有这三个领域，特别侧重于老龄化的各个方面。特别是，我们评估如何“自由基”，所以经常确定在我们的食物和葡萄酒的好和坏，对生物体施加选择，以及对自由基的抵抗（和防御）是否可能推动野外老化的进化，其与生育力和繁殖力的权衡，以及它是如何受到有性或无性生殖的影响。尽管在实验室里做了出色的工作，但这是第一次在“真实的世界”中这样做，并将扩大澳大利亚在进化生物学方面的良好声誉。