Molecular aggression: variation and heritability of the levels of reactive oxygen species, and their effects on the evolution of life histories in the wild

自亚里士多德（公元前300年）以来，生物学的三个领域一直吸引着每一代人——性别、胚胎学和衰老。该提案针对所有这三个领域，特别关注老龄化方面。特别是，我们评估了“自由基”（通常在我们的食物和葡萄酒中被认为是好的和坏的）是如何对生物体施加选择的，以及对自由基的抵抗（和防御）是否会推动野生环境中衰老的进化，它与生育能力和繁殖力的权衡，以及它是如何受到有性或无性生殖的影响的。尽管在实验室里的工作非常出色，但这是在“现实世界”中首次尝试这样做，并将扩大澳大利亚在进化生物学方面的卓越声誉。

Three areas of biology have intrigued every generation since Aristotle (c. 300 BC)- sex, embryology, and ageing. This proposal targets all three of these areas with a special focus on aspects of ageing. In particular, we assess how 'free radicals', so often identified in our food and wine for good and bad, exert selection on living organisms and whether resistance (and defense) towards free radicals may drive evolution of ageing in the wild, its trade offs with fertility and fecundity, and how it is influenced by sexual or non-sexual reproduction. In spite of excellent work in the laboratory, this is the first attempt to do this in 'the real world' and will extend Australia's excellent reputation in evolutionary biology.