Meeting: 2018 pre-Association of Biology Laboratory Educators (ABLE) meeting hands-on workshop for introducing CRISPR-Cas9 technology to undergraduate instructors

会议：2018年生物实验室教育者协会（ABLE）会前会议向本科生导师介绍CRISPR-Cas9技术的实践研讨会

• 批准号: 1823595
• 负责人: Michael Wolyniak
• 金额: $ 4.55万
• 依托单位: Hampden-Sydney College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-04-01 至 2019-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1823595&HistoricalAwards=false
• 关键词: Meeting; 2018; pre; Association; Biology

Genome engineering and editing technologies using CRISPR-Cas9 and other programmable nucleases are rapidly entering mainstream molecular biology research. The emergence of these technologies presents a significant challenge to biological science instructors to provide engaging and effective ways to introduce these technologies into their classrooms. This workshop aims at introducing CRISPR-Cas9 technology to instructors in the context of information flow and the Central Dogma of Molecular Biology, allowing integration of these new technologies into the biological sciences framework. Workshop participants will develop hands-on skills for designing and using genome engineering and editing, and methods for incorporating these technologies into classroom discussions at their institutions.This award supports a 3-day workshop from June 16-18, 2018 at The Ohio State University in Columbus, Ohio on the development and implementation of CRISPR-Cas9 technology for undergraduate instructors from different types of institutions as a prelude to the Association of Biology Laboratory Educators (ABLE). Faculty will be recruited from all types of undergraduate institutions, including minority-serving institutions and two-year institutions. Faculty participants will work together to (a) become conversant with background knowledge and lab skills relating to CRISPR-Cas9 technology, (b) bring different aspects of the technology into their classrooms/labs, (c) discuss and create pedagogical modules suitable to different types of classrooms/labs, and (d) foster and provide support to undergraduate educators who will disseminate gene engineering/editing technologies and make innovations in their classrooms/labs. Specifically, the meeting will encourage the teaching of CRISPR-Cas9 technologies to undergraduates in the context of biological information flow and the Central Dogma of Molecular Biology. Dissemination plans include posting workshop materials on CURE net (https://curenet.cnsutexas.edu), a repository of course-based undergraduate research experiences (CUREs).This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

使用CRISPR-Cas9和其他可编程核酸酶的基因组工程和编辑技术正在迅速进入主流分子生物学研究。 这些技术的出现对生物科学教师提出了一个重大挑战，即提供参与和有效的方式将这些技术引入课堂。本次研讨会旨在向教师介绍CRISPR-Cas9技术在信息流和分子生物学中心法则的背景下，使这些新技术融入生物科学框架。研讨会参与者将开发设计和使用基因组工程和编辑的实践技能，以及将这些技术纳入其机构课堂讨论的方法。该奖项支持2018年6月16日至18日在哥伦布的俄亥俄州州立大学举行的为期3天的研讨会，俄亥俄州关于CRISPR的开发和实施-Cas9技术为来自不同类型机构的本科生教师提供，作为生物学实验室教育工作者协会（ABLE）的前奏。教师将从所有类型的本科院校招聘，包括少数民族服务院校和两年制院校。教师参与者将共同努力（a）熟悉与CRISPR-Cas9技术相关的背景知识和实验室技能，（B）将技术的不同方面带入他们的教室/实验室，（c）讨论和创建适合不同类型教室/实验室的教学模块，以及（d）培养和支持本科教育工作者，他们将传播基因工程/编辑技术，并在课堂上进行创新，labs.具体来说，会议将鼓励在生物信息流和分子生物学中心法则的背景下向本科生教授CRISPR-Cas9技术。 传播计划包括在CURE网（https：//www.example.com）上发布研讨会材料，CURE网是基于课程的本科生研究经验（CURE）的存储库。该奖项反映了NSF的法定使命，并被认为值得通过使用基金会的知识价值和更广泛的影响审查标准进行评估来支持。curenet.cnsutexas.edu