Meeting: Hands-on Workshop for Building Working Groups of CRISPR-Cas9 Undergraduate Educators

会议：建立 CRISPR-Cas9 本科教育工作者工作组实践研讨会

• 批准号: 1916486
• 负责人: Michael Wolyniak
• 金额: $ 4.88万
• 依托单位: Hampden-Sydney College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-05-15 至 2020-04-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1916486&HistoricalAwards=false
• 关键词: Meeting; Hands; Workshop; Building; Working

Providing effective and engaging laboratory experiences is an important part of the effort to improve undergraduate biology education. Introducing current and cutting-edge topics to undergraduate students keeps them excited and brings relevance to the material being studied. The rapidly emerging technology of genomic engineering using programmable nucleases like the CRISPR-Cas9 system is a topic that is both scientifically exciting and socially relevant. As CRISPR-Cas9 continues its meteoric rise into mainstream molecular biology, it is essential for students to learn how to work with it. To that end, this award will support a four-day workshop at the University of Minnesota-Twin Cities that builds on the momentum of a similar project in 2018. The overall goal of the conference organizers is to expand the development and propagation of effective CRISPR-Cas9 tools across multiple model systems. At the conference a group of "veterans" from the 2018 workshop will join CRISPR-Cas9 experts across several popular model systems to work with a new cohort of undergraduate-focused instructors towards three objectives. The first is to foster "big sibling/little sibling" working groups between 2018 workshop alumni and new 2019 participants that can sustain the experiences from the workshop. The second is to share the successful implementation efforts of participants from the 2018 workshop, improve previously implemented pedagogical modules, and create new ones beyond the scope of the original zebrafish workflow suitable to different types of classrooms/labs. Finally, the conference will continue to foster and provide support to the undergraduate educators to disseminate gene engineering/editing technologies and make innovations to their classrooms/labs. The long-term goal of this workshop is to form small, regional groups of experienced and new instructors that can support each other both locally and nationally and to develop online resources that will allow these groups to publicly share their insights with the education community.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

提供有效和引人入胜的实验室经验是努力提高本科生物学教育的重要组成部分。向本科生介绍当前和前沿的主题使他们感到兴奋，并与正在研究的材料相关。使用可编程核酸酶（如CRISPR-Cas9系统）的基因组工程技术迅速崛起，这是一个既令人兴奋又具有社会意义的话题。随着CRISPR-Cas9在主流分子生物学中的迅速崛起，学生们必须学会如何使用它。为此，该奖项将支持明尼苏达大学双城分校为期四天的研讨会，该研讨会将建立在2018年类似项目的基础上。会议组织者的总体目标是在多个模型系统中扩展有效CRISPR-Cas9工具的开发和传播。在这次会议上，来自2018年研讨会的一群“老兵”将加入CRISPR-Cas9专家在几个流行的模型系统，与一个新的以本科生为重点的教师队伍合作，实现三个目标。首先是在2018年研讨会校友和2019年新参与者之间培养“大兄弟/小兄弟”工作组，以维持研讨会的经验。第二个是分享2018年研讨会参与者的成功实施工作，改进以前实施的教学模块，并创建超出原始斑马鱼工作流程范围的新模块，适用于不同类型的教室/实验室。最后，会议将继续促进和支持本科教育工作者传播基因工程/编辑技术，并在他们的教室/实验室进行创新。本次研讨会的长期目标是形成小，由经验丰富的和新的教师组成的区域团体，可以在当地和全国范围内相互支持，并开发在线资源，使这些团体能够与教育界公开分享他们的见解。该奖项反映了NSF的法定使命，并被认为值得通过使用基金会的知识价值和更广泛的影响审查进行评估来支持的搜索.