2018 GRC Signal Transduction by Engineered Extracellular Matrices

该奖项为学生和年轻研究人员的旅行和会议注册费提供支持，作为2018年7月21日至27日在马里兰州安多弗举行的戈登研究会议信号转导工程细胞外基质的参与者。会议将允许年轻的研究人员与成熟的研究人员建立网络，讨论关于细胞如何响应其环境以及如何开发材料来指导这种响应的前沿研究。 这项研究的总体目标是开发疾病模型，重点是癌症，并支持免疫调节治疗的工程材料的设计。本次戈登会议将汇集生物医学工程，材料科学，合成生物学，遗传学，和临床医学，讨论细胞信号传导领域研究的前沿以及驱动和管理材料的开发细胞反应。 这是一个跨学科的会议，旨在建立领域之间的桥梁，以推进这一领域的科学和工程-这是组织工程和细胞治疗学许多领域的关键。 特别是，会议将重点关注对使用工程材料创建疾病模型（特别强调癌症）的基本理解，合成支架的应用，以指导离体组织和类器官的形态发生，以及用于免疫调节治疗的工程材料的设计。 小型会议将包括广泛的研究人员，从研究生和博士后学员到该领域的世界领导者，以传播最新进展并建立联系，以推动这一关键研究领域向前发展。 奖励资金将用于支持学生和受训者，使他们能够展示他们的研究，并发展必要的研究网络，以促进科学和他们的职业生涯。该奖项反映了NSF的法定使命，并已被认为是值得通过使用基金会的智力价值和更广泛的影响审查标准进行评估的支持。

This award provides support for the travel and conference registration fees of students and young investigators as participants in the 2018 Gordon Research Conference Signal Transduction by Engineered Extracellular Matrices, in Andover, Maryland, from July 21-27, 2018. The meeting will allow young investigators to network with establish researchers to discuss cutting edge research about how cells respond to their environment and how materials can be developed to direct this response. The overarching goal of this research is to develop models of disease, with a focus on cancer, and support the design of engineered materials for immunomodulation therapy.This Gordon Conference will bring together researchers in biomedical engineering, materials science, synthetic biology, genetics, and clinical medicine to discuss the cutting edge of research in the area of cellular signal transduction and the development of materials to drive and govern cellular response. This is a cross-disciplinary conference, designed to build bridges between fields to advance science and engineering in this area -- which is key to many areas of tissue engineering and cellular therapeutics. In particular, the conference will focus on fundamental understanding of the use of engineered materials to create disease models (with a special emphasis on cancer), the application of synthetic scaffolds to guide the morphogenesis of ex vivo tissues and organoids, and the design of engineered materials for use in immunomodulation therapies. The small conference will include a broad range of researchers, from graduate students and post-doctoral trainees to world leaders in this area, to disseminate the latest advances and develop connections to advance this key field of research moving forward. Award funds will be used to support students and trainees so that they can present their research and develop the research network necessary to advance both science and their careers.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.