Training workshop on genomic methods and analysis for early-career invertebrate systematists

为早期职业无脊椎动物系统学家举办的基因组方法和分析培训研讨会

• 批准号: 1826662
• 负责人: Heather Bracken-Grissom
• 金额: $ 1.92万
• 依托单位: Florida International University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-06-01 至 2019-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1826662&HistoricalAwards=false
• 关键词: Training; workshop; genomic; methods; analysis

Invertebrates represent 95% of animal diversity, yet few genomic resources exist for the group, leaving a great deal of information on gene diversity and function to be discovered. Coordination among limited research efforts is lacking, limiting comparability among projects and in some cases resulting in duplicated efforts. The Global Invertebrate Genomics Alliance (GIGA) is a network of diverse scientists working to coordinate and advance invertebrate research using advanced techniques to shed light on this genomic diversity and guide scientific discoveries. This workshop, hosted at the 3rd bi-annual GlGA Conference, will provide a much-needed training opportunity for graduate students and early-career researchears in the latest cutting-edge approaches for comparative genomics and bioinformatics in systematic biology. The workshop will also get participants actively involved with developing best practices in invertebrate genomics. Workshop participants will be recruited from diverse levels of expertise with a specific effort to target underrepresented minorities. Information from this workshop will be shared with students and the community at large through publicly available learning exercises and tutorials, facilitating information access to minority groups. Material from this workshop will also be showcased through several media outlets to emphasize the link and importance of invertebrate animals to society as well as the power of genomics in studying marine resources and habitats.The few invertebrate genomes that have been fully sequenced reveal major structural differences with vertebrates, unusual frequencies of transposable elements and genomic innovations among other features. Presently, research coordination among scientists carrying out non-model invertebrate genomics research remains sparse or scattered. Additionally, as a whole, the invertebrate systematics community is inadequately trained to work broadly at the genomic level, thus hampering progress elucidating the evolutionary history for most of the life on earth. This workshop will work to position invertebrate systematists at the leading edge of phylogenomics methodology and begin the process of catching up to their vertebrate systematics counterparts. Primary objectives of this workshop are to 1) provide bioinformatics training and support to the community; 2) promote the sharing of data, resources, and future collaborations; 3) disseminate knowledge on the best practices for laboratory protocols and techniques; and 4) inform and support student researchers in the field of invertebrate genomics.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

无脊椎动物代表了95%的动物多样性，但几乎没有基因组资源存在的群体，留下了大量的信息，基因多样性和功能被发现。有限的研究工作之间缺乏协调，限制了项目之间的可比性，并在某些情况下导致工作重复。全球无脊椎动物基因组学联盟（GIGA）是一个由不同科学家组成的网络，致力于利用先进技术协调和推进无脊椎动物研究，以揭示这种基因组多样性并指导科学发现。该研讨会在第三届两年一度的GlGA会议上举办，将为研究生和早期职业研究人员提供最新的系统生物学比较基因组学和生物信息学前沿方法急需的培训机会。该研讨会还将让参与者积极参与开发无脊椎动物基因组学的最佳实践。讲习班的参加者将从不同专业水平征聘，并特别努力针对代表性不足的少数群体。将通过公开的学习练习和辅导，与学生和整个社区分享这次讲习班的信息，促进少数群体获得信息。本次研讨会的材料也将通过几家媒体进行展示，以强调无脊椎动物与社会的联系和重要性，以及基因组学在研究海洋资源和栖息地方面的力量。已完全测序的少数无脊椎动物基因组揭示了与脊椎动物的主要结构差异，转座因子的异常频率和基因组创新等特征。目前，开展非模型无脊椎动物基因组学研究的科学家之间的研究协调仍然稀疏或分散。此外，作为一个整体，无脊椎动物系统学社区没有得到充分的培训，无法在基因组水平上广泛开展工作，从而阻碍了阐明地球上大多数生命进化历史的进展。本次研讨会将致力于将无脊椎动物系统学家定位在基因组学方法的前沿，并开始追赶他们的脊椎动物系统学同行的过程。本次研讨会的主要目标是：1）为社区提供生物信息学培训和支持; 2）促进数据，资源和未来合作的共享; 3）传播实验室协议和技术的最佳实践知识;和4）为无脊椎动物基因组学领域的学生研究人员提供信息和支持。该奖项反映了NSF的法定使命，并被认为值得通过使用基金会的知识价值和更广泛的影响审查标准进行评估。