Experimental assessment of the long-term ecological and evolutionary consequences of engineered nanoparticles

工程纳米颗粒长期生态和进化后果的实验评估

• 批准号: 1833988
• 负责人: Lin Jiang
• 金额: $ 32.25万
• 依托单位: Georgia Tech Research Corporation
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-01-01 至 2022-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1833988&HistoricalAwards=false
• 关键词: Experimental; assessment; long; term; ecological

Nanomaterials are materials with at least one critical dimension below 100 nm. Engineered nanomaterials, which constitute the building blocks of modern nanotechnology, are those engineered and manufactured by humans. Many engineered nanomaterials, including nanoparticles, nanotubes, and nanowires, display novel physical and chemical properties that are desirable for applications within the medical, industrial, commercial, and environmental sectors. As a result, a large number of commercial products using nanotechnology have been on the market, with thousands of tons of nanomaterials being produced each year. However, with the rapid development of nanotechnology, there is a greater risk for people and environment to be exposed to more nanotechnology-based products. Indeed, nanomaterials are known to enter the environment through both intentional and unintentional releases. Thus, a comprehensive understanding of the environmental impacts of nanomaterials is needed. However, much of the research on the environmental impacts of nanomaterials has focused on the responses of individual organisms or species after short-term exposure (from a few hours to a few days) to nanomaterials. There is little knowledge on how ecological communities, in which organisms interact with individuals of the same and other species, respond to engineered nanomaterials on longer timescales. It is imperative to fill this knowledge gap so that we can avoid potentially serious environmental consequences. In recognition of this pressing issue, this project, led by Lin Jiang and Yongsheng Chen of Georgia Institute of Technology, will investigate the long-term ecological and evolutionary consequences of cerium oxide (CeO2) nanoparticles, a type of metal oxide nanoparticle with various industrial applications. The findings of this project will contribute to a more complete understanding of the effects of engineered nanomaterials on the natural ecosystem. The project will also provide high-quality research training for graduate and undergraduate students, including those from underrepresented groups. Building on their previous work on the molecular, cellular, and species-level responses to engineered nanoparticles, the research team will use freshwater bacteria and protozoans as model organisms to evaluate the novel hypothesis that nanoparticles influence the strength of interactions between species, often more strongly than their non-nanoparticle counterparts, with ensuing consequences for population dynamics, community assembly, and biodiversity evolution. This project will fill a significant gap in our knowledge by applying ecological principles to understanding the effects of nanoparticles on species interactions and associated consequences. The proposed research will advance knowledge in four specific areas. First, it will address potential dynamical consequences of nanoparticles by studying their impacts on predator-prey interactions and population dynamics. Second, it will explore the likelihood that nanoparticles alter outcomes of competition by changing species relative competitive ability. Third, it will test the idea that nanoparticles may influence community assembly through modifying interactions between earlier and later colonizing species. Fourth, it will extend nanotoxicity investigations to the evolutionary timescale by investigating nanoparticle impacts on adaptive radiation. Consequently, the proposed research marries nanotoxicology with population biology and community ecology, contributing to the further development of nanotoxicology as an emerging discipline.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

纳米材料是指至少有一个临界尺寸小于100纳米的材料。工程纳米材料是由人类设计和制造的，它构成了现代纳米技术的基石。许多工程纳米材料，包括纳米颗粒、纳米管和纳米线，显示出新的物理和化学特性，在医疗、工业、商业和环境领域的应用是理想的。因此，大量使用纳米技术的商业产品已经进入市场，每年生产数千吨纳米材料。然而，随着纳米技术的快速发展，越来越多的纳米技术产品将给人类和环境带来更大的风险。事实上，已知纳米材料通过有意和无意的释放进入环境。因此，有必要全面了解纳米材料对环境的影响。然而，许多关于纳米材料对环境影响的研究都集中在个体生物或物种在短期（从几小时到几天）暴露于纳米材料后的反应上。关于生态群落如何在更长的时间尺度上对工程纳米材料作出反应，人们知之甚少。在生态群落中，生物与同一物种和其他物种的个体相互作用。填补这一知识空白是当务之急，这样我们才能避免潜在的严重环境后果。认识到这一紧迫问题，该项目由乔治亚理工学院的蒋林和陈永胜领导，将研究氧化铈纳米颗粒（CeO2）的长期生态和进化后果，氧化铈纳米颗粒是一种具有多种工业应用的金属氧化物纳米颗粒。该项目的研究结果将有助于更全面地了解工程纳米材料对自然生态系统的影响。该项目还将为研究生和本科生提供高质量的研究培训，包括来自代表性不足群体的学生。该研究小组将基于他们先前对工程纳米颗粒的分子、细胞和物种水平反应的研究，利用淡水细菌和原生动物作为模式生物来评估纳米颗粒影响物种之间相互作用强度的新假设，这种影响往往比它们的非纳米颗粒对应物更强烈，从而对种群动态、群落组装和生物多样性进化产生后续影响。这个项目将通过应用生态学原理来理解纳米粒子对物种相互作用和相关后果的影响，填补我们知识上的重大空白。拟议的研究将推进四个具体领域的知识。首先，它将通过研究纳米粒子对捕食者-猎物相互作用和种群动态的影响来解决潜在的动力学后果。其次，它将探讨纳米颗粒通过改变物种的相对竞争能力来改变竞争结果的可能性。第三，它将测试纳米颗粒可能通过改变早期和后期殖民物种之间的相互作用来影响群落组装的想法。第四，通过研究纳米粒子对适应性辐射的影响，将纳米毒性研究扩展到进化时间尺度。因此，该研究将纳米毒理学与种群生物学和群落生态学相结合，有助于纳米毒理学作为一门新兴学科的进一步发展。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

项目成果

Different assembly mechanisms of leaf epiphytic and endophytic bacterial communities underlie their higher diversity in more diverse forests

• DOI: 10.1111/1365-2745.14084
• 发表时间: 2023-03
• 期刊: Journal of Ecology
• 影响因子: 5.5
• 作者: Xian Yang;Pandeng Wang;B. Xiao;Qianna Xu;Q. Guo;Shaopeng Li;Lulu Guo;M. Deng;Jianbo Lu;Lingli Liu;K. Ma;B. Schmid;Lin Jiang

Prevention of algaculture contamination using pesticides for biofuel production

使用农药生产生物燃料来预防藻类养殖污染

• DOI: 10.1016/j.algal.2020.101975
• 发表时间: 2020
• 期刊: Algal Research
• 作者: Van Ginkel, Steven W.;El-Sayed, Waleed M.M.;Johnston, Rachel;Narode, Asmita;Lee, Hwa Jong;Bhargava, Aditya;Snell, Terry;Chen, Yongsheng
• 通讯作者: Chen, Yongsheng

Experimental demonstration of the importance of keystone communities for maintaining metacommunity biodiversity and ecosystem functioning

实验证明关键群落对于维持元群落生物多样性和生态系统功能的重要性

• DOI: 10.1007/s00442-020-04693-x
• 发表时间: 2020
• 期刊: Oecologia
• 影响因子: 2.7
• 作者: Yang, Xian;Tan, Jiaqi;Sun, Kevin Harry;Jiang, Lin
• 通讯作者: Jiang, Lin

Warming alters plant phylogenetic and functional community structure

• DOI: 10.1111/1365-2745.13448
• 发表时间: 2020-07
• 期刊: Journal of Ecology
• 影响因子: 5.5
• 作者: Juntao Zhu;Yang-jian Zhang;Xian Yang;Ning Chen;Shaopeng Li;Pandeng Wang;Lin Jiang

Influence of the Exclusion-Enrichment Effect on Ion Transport in Two-Dimensional Molybdenum Disulfide Membranes

排阻富集效应对二维二硫化钼膜中离子传输的影响

• DOI: 10.1021/acsami.1c03832
• 发表时间: 2021
• 期刊: ACS Applied Materials & Interfaces
• 影响因子: 9.5
• 作者: Tong, Xin;Liu, Su;Zhao, Yangying;Chen, Yongsheng;Crittenden, John
• 通讯作者: Crittenden, John