MRI: Acquisition of a Duo Source Single Crystal X-ray Diffractometer for the Center for X-ray Crystallographic Research

该奖项由主要研究仪器和化学仪器计划支持。来自密歇根州立大学的Aaron Odom教授及其同事米尔顿史密斯、Babak Borhan、Robert LaDuca和Richard Lunt正在购买一台双源单晶衍射仪。一般来说，X射线衍射仪允许准确和精确地测量分子的完整三维结构，包括键距和角度，并提供关于分子相对于相邻分子的空间排列的准确信息。这里描述的研究影响了许多领域，包括有机和无机化学，材料化学和生物化学。该仪器是该机构化学和生物化学本科生和研究生教学、研究和研究培训的组成部分。该设施作为一个区域XRD资源受益的学生和教师主要是本科院校在密歇根州以及那些来自其他学院和大学在美国各地，包括爱达荷州大学、亚拉巴马A M大学、宾厄姆顿大学、格鲁吉亚州立大学和达特茅斯大学。2该奖项旨在加强各级的研究和教育。该衍射仪特别用于开发使用钛生成药理活性杂环的工艺以及研究钴催化的碳-氢硼化反应。它也被用于研究脆性，高熔点金属间化合物，通常被称为Zintl物种用于热电，其中温度差产生电势或反之亦然，以及用于光电子学的材料。该仪器有助于研究地衣代谢物的抗菌，抗真菌和抗氧化活性。与奥克兰大学和达特茅斯大学合作，衍射仪被用于生物无机模型的研究和光敏复合物的研究。该奖项反映了NSF的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

This award is supported by the Major Research Instrumentation and the Chemical Instrumentation Programs. Professor Aaron Odom from Michigan State University and colleagues Milton Smith, Babak Borhan, Robert LaDuca and Richard Lunt are acquiring a dual source single crystal diffractometer. In general, an X-ray diffractometer allows accurate and precise measurements of the full three-dimensional structure of a molecule, including bond distances and angles, and provides accurate information about the spatial arrangement of a molecule relative to neighboring molecules. The studies described here impact many areas, including organic and inorganic chemistry, materials chemistry and biochemistry. This instrument is an integral part of teaching as well as research and research training of undergraduate and graduate students in chemistry and biochemistry at this institution. The facility serves as a regional XRD resource benefitting students and faculty from primarily undergraduate institutions within the state of Michigan as well as those from other colleges and universities around the U.S., including University of Idaho, Alabama A&M University, Binghamton University, Georgia State University and Dartmouth University.The award is aimed at enhancing research and education at all levels. The diffractometer is especially used in developing processes using titanium to generate pharmacologically-active heterocycles and for studying cobalt-catalyzed carbon-hydrogen borylation reactions. It is also employed for studying brittle, high-melting intermetallic compounds commonly referred to as Zintl species used for thermoelectrics for which either a temperature difference creates an electrical potential or vice versa as well as materials for photovoltaics. The instrument aids investigations of lichen metabolites with antibacterial, antifungal and antioxidant activities. In collaboration with Oakland and Dartmouth Universities, the diffractometer is used in studies of bioinorganic models and studies of photoactive complexes.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.