MRI: Acquisition of a Confocal Microscopy System for Biological and Bioengineering Research
MRI:获取用于生物和生物工程研究的共焦显微镜系统
基本信息
- 批准号:1920251
- 负责人:
- 金额:$ 43.18万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Standard Grant
- 财政年份:2019
- 资助国家:美国
- 起止时间:2019-09-01 至 2023-08-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
An award is made to Saint Louis University to acquire a laser scanning confocal microscope (LSCM) to expand the research and educational capabilities of the basic science departments located on the Frost Campus. The most highly impacted departments include Biology, Chemistry, Psychology, and Biomedical and Civil Engineering. The instrument also services the LSCM needs of the Department of Mathematics and Natural Sciences at Harris Stowe State University. This instrument has impacts beyond the research laboratory and is used to prepare our future STEM workforce through the training of postdoctoral fellows, graduate and undergraduate students in fluorescence microscopy, both in research labs and in classrooms. The instrument augments the research experiences of many local high school students, who gain experience with LSCM through various science apprenticeship programs that involve many of our campus researchers. The project also supports an initiative directed at inspiring local middle school students to pursue careers in STEM fields.The instrument is used in a variety of important research areas, including in studies of cardiac function with varying oxygen availability, the basic mechanisms of neuronal synapse formation, eye development, and of novel materials for growing cells in culture. It is being used to develop unique fluorescent compounds that can be used by many scientists to study basic cellular functions. Other biologists and bioengineers use the instrument to study bacteria in water treatment, and the basic mechanisms of cell signaling, gene expression, and tissue regeneration. The results of these research projects will be disseminated in peer-reviewed publications and at scientific meetings.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
授予圣刘易斯大学一个奖项,以获得激光扫描共聚焦显微镜(LSCM),以扩大位于弗罗斯特校园的基础科学部门的研究和教育能力。受影响最大的部门包括生物学,化学,心理学,生物医学和土木工程。该仪器还服务于哈里斯斯托州立大学数学和自然科学系的LSCM需求。该仪器的影响超出了研究实验室,并用于通过在研究实验室和教室中对博士后研究员,研究生和本科生进行荧光显微镜培训来准备我们未来的STEM劳动力。该仪器增加了许多当地高中学生的研究经验,他们通过各种科学学徒计划获得了LSCM的经验,这些计划涉及我们的许多校园研究人员。该项目还支持一项旨在激励当地中学生从事STEM领域职业的倡议。该仪器用于各种重要的研究领域,包括研究不同氧可用性的心脏功能,神经元突触形成的基本机制,眼睛发育以及培养细胞的新材料。它被用于开发独特的荧光化合物,可用于许多科学家研究基本的细胞功能。其他生物学家和生物工程师使用该仪器研究水处理中的细菌,以及细胞信号传导,基因表达和组织再生的基本机制。这些研究项目的结果将在同行评审的出版物和科学会议上传播。该奖项反映了NSF的法定使命,并被认为值得通过使用基金会的知识价值和更广泛的影响审查标准进行评估来支持。
项目成果
期刊论文数量(8)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Tumor Spheroid Fabrication and Encapsulation in Polyethylene Glycol Hydrogels for Studying Spheroid-Matrix Interactions
肿瘤球体的制备和封装在聚乙二醇水凝胶中用于研究球体-基质相互作用
- DOI:10.3791/65515
- 发表时间:2023
- 期刊:
- 影响因子:0
- 作者:Bruns, Joseph;Nejat, Shabnam;Faber, Allison;Zustiak, Silviya P.
- 通讯作者:Zustiak, Silviya P.
Hydrogel matrix presence and composition influence drug responses of encapsulated glioblastoma spheroids
- DOI:10.1016/j.actbio.2021.05.005
- 发表时间:2021-09-06
- 期刊:
- 影响因子:9.7
- 作者:Hill, L.;Bruns, J.;Zustiak, Silviya P.
- 通讯作者:Zustiak, Silviya P.
Differential Effects of the G-Protein-Coupled Estrogen Receptor (GPER) on Rat Embryonic (E18) Hippocampal and Cortical Neurons
- DOI:10.1523/eneuro.0475-21.2022
- 发表时间:2022-07-01
- 期刊:
- 影响因子:3.4
- 作者:Pemberton,Kyle;Rosato,Martina;Xu,Fenglian
- 通讯作者:Xu,Fenglian
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Daniel Warren其他文献
Rapid Quantitation of Substance P in Plasma Using Differential Mobility Spectrometry and Micro flow Liquid Chromatography
使用差动迁移谱和微流液相色谱法快速定量血浆中的 P 物质
- DOI:
- 发表时间:
2016 - 期刊:
- 影响因子:0
- 作者:
Daniel Warren;S. Maitra - 通讯作者:
S. Maitra
Hypothermic machine perfusion prevents hyperacute graft loss in pig-to-primate kidney xenotransplantation after 5-hours of cold Ischemia
在 5 小时的冷缺血后,低温机器灌注可防止猪到灵长类动物肾异种移植中的超急性移植物丢失
- DOI:
10.1038/s43856-025-00842-6 - 发表时间:
2025-04-15 - 期刊:
- 影响因子:6.300
- 作者:
Yu Hisadome;Daniel L. Eisenson;WeiLi Chen;Alexander C. Schulick;Adam Luo;Michelle R. Santillan;Kelly Casella;Du Gu;Mitsuhiro Sekijima;Hisashi Sahara;Daniel Warren;Andrew Cameron;Hayato Iwase;Eugene Shenderov;Kazuhiko Yamada - 通讯作者:
Kazuhiko Yamada
Su1453 LARGE DUCT CHRONIC PANCREATITIS AND EXOCRINE INSUFFICIENCY PREDICT INCREASED FIBROSIS IN PATIENTS UNDERGOING TOTAL PANCREATECTOMY WITH ISLET AUTOTRANSPLANTATION (TPIAT)
- DOI:
10.1016/s0016-5085(24)02223-6 - 发表时间:
2024-05-18 - 期刊:
- 影响因子:
- 作者:
Aida A. Metri;Mahya Faghih;Elizabeth Thompson;Michaël Noë;Rifat Mannan;Rita Kalyani;Elham Afghani;Venkata S. Akshintala;Zahra Yousefli;Daniel Warren;Niraj M. Desai;Zhaoli Sun;Christi Walsh;Martin Makary;Ralph Hruban;Jin He;Vikesh Singh - 通讯作者:
Vikesh Singh
A multi-institutional meningioma MRI dataset for automated multi-sequence image segmentation
用于自动多序列图像分割的多机构脑膜瘤 MRI 数据集
- DOI:
10.1038/s41597-024-03350-9 - 发表时间:
2024 - 期刊:
- 影响因子:9.8
- 作者:
D. Labella;O. Khanna;Shan McBurney;Ryan McLean;Pierre Nedelec;Arif Rashid;N. Tahon;Talissa Altes;Ujjwal Baid;Radhika Bhalerao;Yaseen Dhemesh;Scott Floyd;Devon Godfrey;Fathi Hilal;A. Janas;A. Kazerooni;Collin Kent;John Kirkpatrick;F. Kofler;Kevin Leu;Nazanin Maleki;Bjoern H Menze;Maxence Pajot;Z. Reitman;J. Rudie;Rachit Saluja;Yury Velichko;Chunhao Wang;Pranav I. Warman;Nico Sollmann;David Diffley;K. Nandolia;Daniel Warren;Ali Hussain;John Pascal Fehringer;Yulia Bronstein;Lisa Deptula;Evan G. Stein;Mahsa Taherzadeh;Eduardo Portela de Oliveira;Aoife Haughey;Marinos Kontzialis;L. Saba;Benjamin Turner;Melanie M T Brüßeler;Shehbaz M Ansari;Athanasios Gkampenis;D. Weiss;Aya Mansour;I. Shawali;Nikolay Yordanov;Joel M. Stein;Roula Hourani;Mohammed Yahya Moshebah;A. Abouelatta;Tanvir Rizvi;Klara Willms;Dann C. Martin;Abdullah Okar;Gennaro D'Anna;Ahmed Taha;Yasaman Sharifi;S. Faghani;Dominic Kite;Marco C. Pinho;Mohammad Ammar Haider;M. Alonso;J. Villanueva;A. Rauschecker;A. Nada;Mariam Aboian;A. Flanders;S. Bakas;Evan Calabrese - 通讯作者:
Evan Calabrese
1153 A COMPARATIVE EVALUATION OF FIBROSIS AMONG PATIENTS WITH RECURRENT ACUTE AND CHRONIC PANCREATITIS UNDERGOING TOTAL PANCREATECTOMY WITH ISLET AUTOTRANSPLANTATION (TPIAT)
- DOI:
10.1016/s0016-5085(24)01106-5 - 发表时间:
2024-05-18 - 期刊:
- 影响因子:
- 作者:
Aida A. Metri;Mahya Faghih;Elizabeth Thompson;Michaël Noë;Rifat Mannan;Rita Kalyani;Elham Afghani;Venkata S. Akshintala;Zahra Yousefli;Daniel Warren;Niraj M. Desai;Zhaoli Sun;Christi Walsh;Martin Makary;Ralph Hruban;Jin He;Vikesh Singh - 通讯作者:
Vikesh Singh
Daniel Warren的其他文献
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{{ truncateString('Daniel Warren', 18)}}的其他基金
2022 APS Intersociety Meeting - Comparative Physiology: From Organisms to Omics in an Uncertain World
2022 年 APS 社会间会议 - 比较生理学:不确定世界中从有机体到组学
- 批准号:
2225414 - 财政年份:2022
- 资助金额:
$ 43.18万 - 项目类别:
Standard Grant
CAREER: Integrative Physiology of Anoxia Tolerance in Turtles
职业:海龟耐缺氧的综合生理学
- 批准号:
1253939 - 财政年份:2013
- 资助金额:
$ 43.18万 - 项目类别:
Continuing Grant
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