RCN-UBE: Development of an Inclusive Community for the Instruction of Visualizing Biomolecules

RCN-UBE：开发一个包容性社区，用于生物分子可视化教学

• 批准号: 1920270
• 负责人: Josh Beckham
• 金额: $ 48.75万
• 依托单位: University of Texas at Austin
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-01 至 2024-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1920270&HistoricalAwards=false
• 关键词: RCN; UBE; Development; Inclusive; Community

Today's biochemistry and life sciences students need an understanding of molecular structure if they are to make the critical advances in areas such as personalized medicine, agriculture, and biofuels necessary for the future welfare of humanity. Given the importance of molecular structures, images of biomolecules are extensively used in biochemistry and molecular biology textbooks and classrooms. However, these figures are usually static and do not fully convey complex structure/function relationships that happen in three dimensions, especially to novice undergraduate learners. Furthermore, instructors seldom explore whether students can extract key structural features and relationships from them. This project will develop strategies and assessments for evaluating students' biomolecular visual literacy skills by creating a network of biochemistry and molecular biology instructors. Working in teams, these instructors will develop assessments with improved accessibility for colorblind individuals that probe students' visualization skills. Following a peer-review process, a subset of these tools will be made freely available on an online repository. By working as a trans-institutional community of practice, the network of instructors will facilitate more robust and more universally understood instruction in the visualization of biomolecules.This project will use the previously developed molecular visualization framework at BioMolViz.org. The BioMolViz framework defines twelve overarching themes in visual literacy that are subdivided into learning goals and objectives. To further populate it, assessment instruments will be created to evaluate student progress in achieving the visual literacy learning objectives in the four overarching themes identified by educators in our previous work as being of greatest importance to the community--monomer recognition, alternate rendering, molecular interactions, and structure-function relationships. Following creation and peer review, iteratively revised questions will be piloted in classrooms of network members. Item-response theory will be applied using the Rasch Model to further test the instruments for reliability to determine which items should be included in the online repository. The data collected from these studies will be used to improve the methods for future assessment development and establish a community of practice for the explicit instruction of molecular visualization skills.Co-funding for this project is being provided by the Improving Undergraduate STEM Education (IUSE: EHR) program in recognition of the project's alignment with the overarching goals of the IUSE: EHR program.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

今天的生物化学和生命科学的学生需要了解分子结构，如果他们要在个性化医疗，农业和生物燃料等领域取得关键进展，这些领域对人类未来的福利是必要的。鉴于分子结构的重要性，生物分子的图像被广泛用于生物化学和分子生物学教科书和课堂。然而，这些数字通常是静态的，不能完全传达复杂的结构/功能关系，发生在三个维度，特别是新手本科学习者。此外，教师很少探索学生是否能从中提取关键的结构特征和关系。该项目将通过创建生物化学和分子生物学教师网络来制定评估学生生物分子视觉素养技能的策略和评估。在团队合作中，这些教师将开发评估，提高色盲个人的可访问性，探索学生的可视化技能。经过同行审查后，这些工具的一部分将在网上储存库中免费提供。通过作为一个跨机构的实践社区，教师网络将促进更强大和更普遍理解的生物分子可视化教学。该项目将使用BioMolViz. org上先前开发的分子可视化框架。BioMolViz框架定义了12个视觉素养的总体主题，这些主题被细分为学习目标和目的。为了进一步填充它，将创建评估工具来评估学生在实现视觉素养学习目标方面的进展，这四个主题由教育工作者在我们以前的工作中确定为对社区最重要的主题-单体识别，交替渲染，分子相互作用和结构-功能关系。在创建和同行评审之后，将在网络成员的教室中试用反复修订的问题。将使用Rasch模型应用项目反应理论，进一步测试工具的可靠性，以确定哪些项目应列入在线知识库。从这些研究中收集的数据将用于改进未来评估开发的方法，并建立一个实践社区，以明确指导分子可视化技能。（IUSE：EHR）计划，以表彰该项目与IUSE总体目标的一致性：EHR计划。该奖项反映了NSF的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

项目成果

Teaching Biomolecular Visualization Literacy: Guidelines for Developing Assessments, Images and Rubrics Aligned with the BioMolViz Framework

教授生物分子可视化素养：开发与 BioMolViz 框架一致的评估、图像和评分指南

• DOI: 10.1096/fasebj.2022.36.s1.0r334
• 发表时间: 2022
• 期刊: The FASEB Journal
• 作者: Acevedo, Roderico;Mertz, Pam;Burch, Charmita;Austin, Shane;Nemmara, Venkatesh;Mitton‐Fry, Rachel;Hall, Bonnie;Fox, Kristin;Franzen, Margaret A.;Beckham, Josh
• 通讯作者: Beckham, Josh

Abstract 1536: Evaluating Biomolecular Visual Literacy: A Library of Classroom-Tested Assessments for Instructor Use

摘要 1536：评估生物分子视觉素养：供教师使用的经过课堂测试的评估库

• DOI: 10.1016/j.jbc.2023.103504
• 发表时间: 2023
• 期刊: Journal of Biological Chemistry
• 影响因子: 4.8
• 作者: Beckham, Josh;Procko, Kristen;Engelman, Shelly;Acevedo, Roderico;Dries, Daniel;Franzen, Margaret;Jakubowski, Henry;Mertz, Pamela;Roca, Alberto
• 通讯作者: Roca, Alberto

BioMolViz: A Community to Improve Biomolecular Visual Literacy

BioMolViz：提高生物分子视觉素养的社区

• 发表时间: 2022
• 期刊: Portugal
• 作者: Dries, Daniel R.;Jakubowski, Henry;Beckham, Josh T.;Procko, Kristen
• 通讯作者: Procko, Kristen

Building a Community of Practice for the Assessment of Biomolecular Visual Literacy

建立生物分子视觉素养评估实践社区

• DOI: 10.1096/fasebj.2020.34.s1.00466
• 发表时间: 2020
• 期刊: The FASEB Journal
• 作者: Procko, Kristen;Beckham, Josh T.;Dean, Diane M.;Dries, Dan R.;Engelman, Shelly;Franzen, Margaret A.;Jakubowski, Henry;Novak, Walter R.P.;Porter, Sandra;Roberts, Rebecca
• 通讯作者: Roberts, Rebecca

Identifying Student Misconceptions in Biomolecular Visualization in the Context of the BioMolViz Framework

在 BioMolViz 框架的背景下识别学生对生物分子可视化的误解

• DOI: 10.1096/fasebj.2022.36.s1.0r333
• 发表时间: 2022
• 期刊: The FASEB Journal
• 作者: Roberts, Rebecca;Shor, Audrey C.;Jakubowski, Henry;Austin, Shane;Procko, Kristen;Franzen, Margaret A.
• 通讯作者: Franzen, Margaret A.