SBIR Phase II: e-CHEM: A fully-autonomous connected in-situ chemical sensor
SBIR 第二阶段:e-CHEM:完全自主连接的原位化学传感器
基本信息
- 批准号:1927079
- 负责人:
- 金额:$ 74.37万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Standard Grant
- 财政年份:2019
- 资助国家:美国
- 起止时间:2019-10-01 至 2023-02-28
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
The broader impact/commercial potential of this Small Business Innovation Research (SBIR) project will be on public health, with the proposed "e-CHEM" solution enabling the monitoring of chemical water quality with high temporal resolution, providing early alerts when quality degrades. The World Health Organization has recognized water chemical safety risk management as essential for ensuring public health. By informing water utilities and end-users early on about problems in the drinking water quality or in the distribution infrastructure, the duration of poor tap water quality episodes can be drastically reduced. For the industrial sector, e-CHEM will measure wastewater contamination, allowing its effective treatment and reuse and limiting fresh source water use particularly in regions affected by drought. e-CHEM will have major commercial impact across multiple industries, minimizing costs, reducing liabilities, and improving health.This SBIR Phase II project proposes to commercialize the e-CHEM analyzer developed and pilot-tested in Phase I to provide a complete data analytics solution for performing water quality monitoring autonomously in critical applications where lack of infrastructure (power, communications), location remoteness, or limited human resources currently impose severe constraints. e-CHEM uses novel reagent-based and reagent-less lab-on-chip sensor technology to continuously quantify multiple water contaminants within a highly-miniaturized instrument, with accuracy and sensitivity levels approaching and even surpassing current laboratory capabilities. This Phase II project will involve a combination of fundamental and applied research aimed at improving the e-CHEM prototype for environmental variations during field operations, optimizing and ruggedizing the system for user operations, and developing machine learning algorithms for data analytics. After full validation of e-CHEM technology for drinking water, the e-CHEM system will also be adapted for harsh environments, such as monitoring of industrial wastewater from unconventional oil-and-gas operations.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
这一小型企业创新研究(SBIR)项目将对公众健康产生更广泛的影响/商业潜力,拟议的“e-CHEM”解决方案能够以高时间分辨率监测化学水质,并在水质下降时提供早期警报。世界卫生组织已确认水化学安全风险管理对于确保公众健康至关重要。通过及早告知自来水公司和最终用户饮用水质量或分配基础设施中的问题,可以大大缩短自来水质量不佳的持续时间。对于工业部门,e-CHEM将测量废水污染,使其能够进行有效的处理和再利用,并限制淡水的使用,特别是在受干旱影响的地区。E-CHEM将在多个行业产生重大的商业影响,最大限度地降低成本,减少负债,并改善健康。这个SBIR第二阶段项目建议将在第一阶段开发和试点测试的e-CHEM分析仪商业化,以提供完整的数据分析解决方案,用于在缺乏基础设施(电力、通信)、位置偏远或人力资源有限的关键应用中自动执行水质监测。E-CHEM使用新颖的基于试剂和无试剂的芯片上实验室传感器技术,在高度小型化的仪器中连续定量多种水污染物,准确度和灵敏度水平接近甚至超过当前的实验室能力。这一第二阶段项目将涉及基础研究和应用研究的结合,旨在改进e-CHEM原型以适应外地行动期间的环境变化,优化和加固用于用户操作的系统,并开发用于数据分析的机器学习算法。在饮用水的e-CHEM技术得到充分验证后,e-CHEM系统还将适用于恶劣的环境,例如监测来自非常规石油和天然气作业的工业废水。这一奖项反映了NSF的法定使命,并通过使用基金会的智力优势和更广泛的影响审查标准进行评估,被认为值得支持。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Joyce Wong其他文献
Kiosk 4R-FC-05 - Pre-transplantation Right Ventricular Volumes Are Associated with All-cause Mortality After Lung Transplantation
4R-FC-05 自助服务终端 - 肺移植前右心室容积与肺移植后的全因死亡率相关
- DOI:
10.1016/j.jocmr.2024.100599 - 发表时间:
2024-03-01 - 期刊:
- 影响因子:6.100
- 作者:
Nikolaos Miaris;Georgia Sarri;Anne McDermott;Mandy McCurry;Alessandra Verzelloni Sef;Clarissa Borguezan Daros;John Dunning;Ulrich Stock;Felix Chua;Muhammad Usman;Chiara Bucciarelli-Ducci;Kavita Dave;Vicky Gerovasili;Nandor Marczin;Martin Carby;Anna Reed;Joyce Wong - 通讯作者:
Joyce Wong
487 - Gastric Cancer in the Very Elderly: Benefit of Surgery and Systemic Treatment in a U.S. Population Study
- DOI:
10.1016/s0016-5085(17)34049-0 - 发表时间:
2017-04-01 - 期刊:
- 影响因子:
- 作者:
Erin K. Greenleaf;Christopher S. Hollenbeak;Joyce Wong - 通讯作者:
Joyce Wong
Blood from Highly Allergic Donors Yields High-Affinity IgE Antibodies to Food and Non-food Allergens
高过敏供体的血液产生针对食物和非食物过敏原的高亲和力免疫球蛋白 E 抗体
- DOI:
10.1016/j.jaci.2021.12.537 - 发表时间:
2022-02-01 - 期刊:
- 影响因子:11.200
- 作者:
Derek Croote;Paige Creeks;Johanna Romero;Saba Sohail;Robert Sanchez Rodriguez;Joyce Wong - 通讯作者:
Joyce Wong
Tu1336 - Greater Lymph Node Retrieval Improves Survival in Node-Negative Resected Gastric Cancer
- DOI:
10.1016/s0016-5085(17)34293-2 - 发表时间:
2017-04-01 - 期刊:
- 影响因子:
- 作者:
Katelin Mirkin;Christopher S. Hollenbeak;Joyce Wong - 通讯作者:
Joyce Wong
DE-CMR and MPS for assessment of myocardial viability: to what extent do the two techniques agree?
- DOI:
10.1186/1532-429x-18-s1-p88 - 发表时间:
2016-01-27 - 期刊:
- 影响因子:
- 作者:
Thomas Alway;Charles Butcher;Evangelos Skondros;Richard Underwood;Joyce Wong - 通讯作者:
Joyce Wong
Joyce Wong的其他文献
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{{ truncateString('Joyce Wong', 18)}}的其他基金
SBIR Phase I: Automated In-Situ High-Resolution COVID-19 Wastewater-Based Epidemiology
SBIR 第一阶段:基于废水的自动化原位高分辨率 COVID-19 流行病学
- 批准号:
2041400 - 财政年份:2021
- 资助金额:
$ 74.37万 - 项目类别:
Standard Grant
SBIR Phase I: e-CHEM: A fully-autonomous connected in-situ chemical sensor
SBIR 第一阶段:e-CHEM:完全自主连接的原位化学传感器
- 批准号:
1747293 - 财政年份:2018
- 资助金额:
$ 74.37万 - 项目类别:
Standard Grant
I-Corps: Tissue-engineering vascular grafts using autologous cell sheets
I-Corps:使用自体细胞片进行组织工程血管移植
- 批准号:
1508331 - 财政年份:2015
- 资助金额:
$ 74.37万 - 项目类别:
Standard Grant
PESO: Engineered Platforms to Investigate Molecular Determinants of Tumor Metastasis to Targeted Niche Sites
PESO:研究肿瘤转移至目标位点的分子决定因素的工程平台
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1235316 - 财政年份:2012
- 资助金额:
$ 74.37万 - 项目类别:
Standard Grant
2011 Biomaterials & Tissue Engineering Gordon Research Conference
2011年生物材料
- 批准号:
1118459 - 财政年份:2011
- 资助金额:
$ 74.37万 - 项目类别:
Standard Grant
CAREER: Integrated Research and Educational Program in Cellular Mechanics in Biomedical Engineering
职业:生物医学工程细胞力学综合研究和教育项目
- 批准号:
9985338 - 财政年份:2000
- 资助金额:
$ 74.37万 - 项目类别:
Continuing Grant
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