Collaborative research: RoL: Using reaction norms to link genomic and phenotypic variation with regional-scale population responses to environmental change
合作研究:RoL:利用反应规范将基因组和表型变异与区域规模人口对环境变化的反应联系起来
基本信息
- 批准号:1927177
- 负责人:
- 金额:$ 32.1万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Standard Grant
- 财政年份:2020
- 资助国家:美国
- 起止时间:2020-01-01 至 2024-12-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Rapid environmental changes, such as rising temperatures and nitrogen pollution, can have dramatic impacts on plant and animal species important to society. Endangered species may be driven extinct, damaging invasive species might increase in distribution and abundance, and changes in the production of timber or forage species can alter rural economies. To help natural resource managers make good decisions, biologists predict the effect of environmental change on important species using population models. However, these predictions are rarely tested against observations. As a result, the ability of population models to make accurate forecasts for large regions is unknown. The goal of this project is to build a state-of-the-art population model and rigorously test its predictions against independent observations. The results will establish a benchmark for the current predictive ability of population models, while also identifying the kind of information required to make good predictions. For example, is it possible to make a skillful forecast without understanding genetic differences between individuals from different locations or accounting for interactions between the study species and its competitors? Graduate students and postdoctoral scientists will be invited to workshops for training in advanced statistical and population modeling techniques. To educate the public about the impacts of invasive species and environmental change, interactive exhibits will be installed at three museums and botanical gardens.The proposed research focuses on the reaction norm, a quantitative description of how an organism's performance depends on the environment. Success will require new advances to determine the relative importance of processes operating at gene, individual, and community levels in shaping reaction norms and regional population dynamics. The investigators will integrate DNA sequencing, common environment experiments, a regional network of distributed experiments across abiotic gradients, and new statistical techniques to answer the following questions: 1) What processes influencing reaction norms must we understand to predict impacts of environmental change on regional-scale population dynamics? 2) What is the magnitude of intraspecific variation in reaction norms, and to what extent does it reflect local adaptation vs. other processes? 3) How do phenology and physiology interact to determine demographic responses to weather? 4) How do abiotic conditions and competitive environment combine to influence demographic rates? The focal species is the invasive grass Bromus tectorum, which has degraded millions of acres of sagebrush steppe across the western US. Predictions about future changes in B. tectorum abundance across the region, and resulting changes in fire regimes, will help decision-makers prioritize future investments in conservation and restoration.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
快速的环境变化,如气温上升和氮污染,可能对社会重要的植物和动物物种产生巨大影响。濒危物种可能会灭绝,破坏性的入侵物种可能会增加分布和数量,木材或饲料物种生产的变化可能会改变农村经济。为了帮助自然资源管理者做出正确的决策,生物学家使用种群模型预测环境变化对重要物种的影响。然而,这些预测很少与观测结果进行对比。因此,人口模型对大区域进行准确预测的能力是未知的。该项目的目标是建立一个最先进的人口模型,并严格测试其预测对独立观察。研究结果将为人口模型当前的预测能力建立一个基准,同时还将确定做出良好预测所需的信息类型。例如,是否有可能在不了解来自不同地点的个体之间的遗传差异或考虑研究物种与其竞争对手之间的相互作用的情况下进行熟练的预测?研究生和博士后科学家将被邀请参加高级统计和人口建模技术培训讲习班。为了教育公众有关入侵物种和环境变化的影响,将在三个博物馆和植物园安装互动展品。拟议的研究重点是反应规范,一个生物体的表现如何取决于环境的定量描述。成功将需要新的进展,以确定在基因,个人和社区层面上运作的过程在形成反应规范和区域人口动态的相对重要性。研究人员将整合DNA测序,共同的环境实验,跨非生物梯度分布实验的区域网络,以及新的统计技术来回答以下问题:1)我们必须了解哪些影响反应规范的过程,以预测环境变化对区域规模人口动态的影响?2)反应规范的种内变异的幅度是多少?它在多大程度上反映了当地的适应性与其他过程?3)物候学和生理学如何相互作用来决定人口对天气的反应?4)非生物条件和竞争环境是如何联合收割机影响人口增长率的?焦点物种是入侵草雀麦,它已经使美国西部数百万英亩的山艾树草原退化。对B未来变化的预测。该奖项反映了NSF的法定使命,并通过使用基金会的知识价值和更广泛的影响审查标准进行评估,被认为值得支持。
项目成果
期刊论文数量(4)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Statistical Challenges in Agent-Based Modeling
- DOI:10.1080/00031305.2021.1900914
- 发表时间:2021-04-21
- 期刊:
- 影响因子:1.8
- 作者:Banks, David L.;Hooten, Mevin B.
- 通讯作者:Hooten, Mevin B.
Making Recursive Bayesian Inference Accessible
- DOI:10.1080/00031305.2019.1665584
- 发表时间:2019-10-16
- 期刊:
- 影响因子:1.8
- 作者:Hooten, Mevin B.;Johnson, Devin S.;Brost, Brian M.
- 通讯作者:Brost, Brian M.
Hierarchical computing for hierarchical models in ecology
生态学中分层模型的分层计算
- DOI:10.1111/2041-210x.13513
- 发表时间:2020
- 期刊:
- 影响因子:6.6
- 作者:McCaslin, Hanna M.;Feuka, Abigail B.;Hooten, Mevin B.;O'Hara, ed., Robert B.
- 通讯作者:O'Hara, ed., Robert B.
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Cynthia Brown其他文献
Non-academic admission criterion of certified nursing assistant status for undergraduate nursing programs: A comparative case study.
本科护理课程认证护理助理身份的非学术录取标准:比较案例研究。
- DOI:
10.1016/j.profnurs.2021.07.021 - 发表时间:
2021 - 期刊:
- 影响因子:0
- 作者:
Nancy Capponi;Cynthia Brown - 通讯作者:
Cynthia Brown
Formula with reduced content of improved, partially hydrolyzed protein and probiotics: infant growth and health
改良部分水解蛋白质和益生菌含量减少的配方奶粉:婴儿生长和健康
- DOI:
- 发表时间:
2003 - 期刊:
- 影响因子:0.4
- 作者:
E. Ziegler;Janice M. Jeter;Jean M. Drulis;S. Nelson;F. Haschke;P. Steenhout;Cynthia Brown;J. Maire;C. Hager - 通讯作者:
C. Hager
The Canine Cuteness Effect: Owner-Perceived Cuteness as a Predictor of Human–Dog Relationship Quality
犬类可爱效应:主人感知的可爱度作为人狗关系质量的预测因子
- DOI:
10.1080/08927936.2015.1069992 - 发表时间:
2015 - 期刊:
- 影响因子:0
- 作者:
Pinar Thorn;T. Howell;Cynthia Brown;P. Bennett - 通讯作者:
P. Bennett
CHRONIC OPIOID USE IS ASSOCIATED WITH SIGNIFICANT HIGHER 12-MONTH ALL-CAUSE READMISSION AND ALL-CAUSE MORTALITY BUT NOT ASSOCIATED WITH 30-DAY ALL-CAUSE READMISSION OR ALL-CAUSE MORTALITY IN OLDER MEDICARE BENEFICIARIES HOSPITALIZED FOR HEART FAILURE
- DOI:
10.1016/s0735-1097(16)31429-2 - 发表时间:
2016-04-05 - 期刊:
- 影响因子:
- 作者:
Raymond K. Young;Sarah Goodlin;Wen-Chih Wu;Charity Morgan;Sijian Zhang;Donna Bearden;Marc Blackman;Ross Fletcher;Cynthia Brown;Gregg Fonarow;Prakash Deedwania;Wilbert Aronow;Ioannis Kanonidis;Richard Allman;Ali Ahmed - 通讯作者:
Ali Ahmed
The Impact of Personal-Level Social Networks on Treatment Adherence, Depression, Anxiety, and Perceived Stigma Among Adults with Cystic Fibrosis: An Egocentric Network Analysis
- DOI:
10.1007/s12529-025-10382-x - 发表时间:
2025-07-02 - 期刊:
- 影响因子:1.700
- 作者:
Haosen Sun;Heather M. Francis;Jennifer Polo;Christine Esposito;Katherine Papia;Jana Yeley;Meagan Brant;Alison Huenger;Janice Wang;Cynthia Brown;Erin Pullen;Melissa J. Basile - 通讯作者:
Melissa J. Basile
Cynthia Brown的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Cynthia Brown', 18)}}的其他基金
Collaborative Research: CPATH CB: I18n, Internationalization of Computer Science Education: The Pacific Rim Community Model
合作研究:CPATH CB:I18n,计算机科学教育国际化:环太平洋社区模型
- 批准号:
0722342 - 财政年份:2007
- 资助金额:
$ 32.1万 - 项目类别:
Standard Grant
An Active-Learning Curriculum for Computer Science
计算机科学主动学习课程
- 批准号:
9155929 - 财政年份:1992
- 资助金额:
$ 32.1万 - 项目类别:
Standard Grant
Development of an Undergraduate Laboratory for Presentation of Computer Science Learning Modules for Introductory Courses at Northeastern University.
东北大学本科生实验室的开发,用于介绍计算机科学入门课程的学习模块。
- 批准号:
9152211 - 财政年份:1991
- 资助金额:
$ 32.1万 - 项目类别:
Standard Grant
Applications of Group Theory to Symmetry in Backtrack Trees
群论在回溯树对称性中的应用
- 批准号:
8603293 - 财政年份:1986
- 资助金额:
$ 32.1万 - 项目类别:
Standard Grant
相似国自然基金
Research on Quantum Field Theory without a Lagrangian Description
- 批准号:24ZR1403900
- 批准年份:2024
- 资助金额:0.0 万元
- 项目类别:省市级项目
HIF-1α调控软骨细胞衰老在骨关节炎进展中的作用及机制研究
- 批准号:82371603
- 批准年份:2023
- 资助金额:49.00 万元
- 项目类别:面上项目
TIPE2调控巨噬细胞M2极化改善睑板腺功能障碍的作用机制研究
- 批准号:82371028
- 批准年份:2023
- 资助金额:49.00 万元
- 项目类别:面上项目
PRNP调控巨噬细胞M2极化并减弱吞噬功能促进子宫内膜异位症进展的机制研究
- 批准号:82371651
- 批准年份:2023
- 资助金额:49.00 万元
- 项目类别:面上项目
脐带间充质干细胞微囊联合低能量冲击波治疗神经损伤性ED的机制研究
- 批准号:82371631
- 批准年份:2023
- 资助金额:49.00 万元
- 项目类别:面上项目
超声驱动压电效应激活门控离子通道促眼眶膜内成骨的作用及机制研究
- 批准号:82371103
- 批准年份:2023
- 资助金额:49.00 万元
- 项目类别:面上项目
骨髓ISG+NAMPT+中性粒细胞介导抗磷脂综合征B细胞异常活化的机制研究
- 批准号:82371799
- 批准年份:2023
- 资助金额:47.00 万元
- 项目类别:面上项目
Lienard系统的不变代数曲线、可积性与极限环问题研究
- 批准号:12301200
- 批准年份:2023
- 资助金额:30.00 万元
- 项目类别:青年科学基金项目
RIPK3蛋白及其RHIM结构域在脓毒症早期炎症反应和脏器损伤中的作用和机制研究
- 批准号:82372167
- 批准年份:2023
- 资助金额:48.00 万元
- 项目类别:面上项目
基于MFSD2A调控血迷路屏障跨细胞囊泡转运机制的噪声性听力损失防治研究
- 批准号:82371144
- 批准年份:2023
- 资助金额:49.00 万元
- 项目类别:面上项目
相似海外基金
RoL: COLLABORATIVE RESEARCH: EXTREME ENVIRONMENTS, PHYSIOLOGICAL ADAPTATION, AND THE ORIGIN OF SPECIES
ROL:合作研究:极端环境、生理适应和物种起源
- 批准号:
2423844 - 财政年份:2023
- 资助金额:
$ 32.1万 - 项目类别:
Standard Grant
ROL: COLLABORATIVE RESEARCH: EXTREME ENVIRONMENTS, PHYSIOLOGICAL ADAPTATION, AND THE ORIGIN OF SPECIES
ROL:合作研究:极端环境、生理适应和物种起源
- 批准号:
2311366 - 财政年份:2023
- 资助金额:
$ 32.1万 - 项目类别:
Standard Grant
Collaborative Research: RoL: The intersection between cell fate decisions and phenotypic diversification in a rapidly radiating butterfly lineage
合作研究:RoL:快速辐射蝴蝶谱系中细胞命运决定和表型多样化之间的交叉点
- 批准号:
2110533 - 财政年份:2021
- 资助金额:
$ 32.1万 - 项目类别:
Continuing Grant
Collaborative Research: RoL-Rules for Dynamic-Light Environmental Sculpting of Genomes
合作研究:基因组动态光环境塑造的 RoL 规则
- 批准号:
2034777 - 财政年份:2021
- 资助金额:
$ 32.1万 - 项目类别:
Standard Grant
Collaborative Research: RoL-Rules for Dynamic-Light Environmental Sculpting of Genomes
合作研究:基因组动态光环境塑造的 RoL 规则
- 批准号:
2034929 - 财政年份:2021
- 资助金额:
$ 32.1万 - 项目类别:
Standard Grant
Collaborative Research: RoL: The Evolution of the Genotype-Phenotype Map across Budding Yeasts
合作研究:RoL:出芽酵母基因型-表型图谱的演变
- 批准号:
2110403 - 财政年份:2021
- 资助金额:
$ 32.1万 - 项目类别:
Continuing Grant
Collaborative Research: RoL: The Evolution of the Genotype-Phenotype Map across Budding Yeasts
合作研究:RoL:出芽酵母基因型-表型图谱的演变
- 批准号:
2110404 - 财政年份:2021
- 资助金额:
$ 32.1万 - 项目类别:
Continuing Grant
Collaborative Research: RoL: The intersection between cell fate decisions and phenotypic diversification in a rapidly radiating butterfly lineage
合作研究:RoL:快速辐射蝴蝶谱系中细胞命运决定和表型多样化之间的交叉点
- 批准号:
2110534 - 财政年份:2021
- 资助金额:
$ 32.1万 - 项目类别:
Continuing Grant
Collaborative Research: RoL: The intersection between cell fate decisions and phenotypic diversification in a rapidly radiating butterfly lineage
合作研究:RoL:快速辐射蝴蝶谱系中细胞命运决定和表型多样化之间的交叉点
- 批准号:
2110532 - 财政年份:2021
- 资助金额:
$ 32.1万 - 项目类别:
Continuing Grant
IIBR RoL: Collaborative Research: A Rules Of Life Engine (RoLE) Model to Uncover Fundamental Processes Governing Biodiversity
IIBR RoL:协作研究:揭示生物多样性基本过程的生命规则引擎 (RoLE) 模型
- 批准号:
2104147 - 财政年份:2020
- 资助金额:
$ 32.1万 - 项目类别:
Standard Grant