SBIR Phase II: Remediation of recalcitrant and emerging environmental organic contaminants of concern using bacterial approaches

SBIR 第二阶段：使用细菌方法修复令人担忧的顽固性和新出现的环境有机污染物

• 批准号: 1927687
• 负责人: Raymond Sambrotto
• 金额: $ 71.16万
• 依托单位: ALLIED MICROBIOTA LLC
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-15 至 2022-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1927687&HistoricalAwards=false
• 关键词: SBIR; Phase; II; Remediation; recalcitrant

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) project is addressing the critical societal need to remediate toxic organic pollutants in soils and sediments. The proposed technology would enable environmental goals to be met on many contaminated sites whose remediation is currently limited by high costs. The technology would contribute to the re-development of many billions of dollars in real estate by returning properties to productive and appropriate use. The hybrid bacterial augmentation and thermal technology provides a model for additional systems with other bacteria uniquely suited to applications in emerging contaminants and water treatment.This project proposes to commercialize a bacterial treatment for the degradation of organic contaminants of concern in environmental matrices such as soils and sediments. The thermally-enhanced bioaugmentation technology evaluated in Phase I is based on a novel bacterial strain and its enzymes that function at elevated temperatures and are capable of degrading a variety of ring based, organic pollutants, including chlorinated forms difficult to remediate. Pilot tests on soils contaminated with Total Petroleum Hydrocarbons (TPH) demonstrated degradation for both TPH and for the heavier poly-aromatic hydrocarbons (PaHs) on the EPA's list of priority pollutants. Phase II goals are to expand these initial studies to the full commercial scale of 100s to 1000s of tons of soil by working with established environmental engineering firms with extensive experience in thermal treatments of large volumes. To fully commercialize this new technology, the production capacity for the biological agents also will be scaled up by over an order of magnitude. The technology will be applied both ex-situ and in-situ as the process evolves.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

这一小型企业创新研究(SBIR)项目的广泛影响/商业潜力正在解决修复土壤和沉积物中有毒有机污染物的关键社会需求。拟议的技术将使许多受污染的场地能够实现环境目标，这些场地的补救目前受到高昂成本的限制。这项技术将有助于重新开发价值数十亿美元的房地产，使物业重新得到有效和适当的使用。混合细菌增强和热技术为其他细菌提供了一个额外系统的模型，这些细菌特别适合于新出现的污染物和水处理应用。该项目提议将一种用于降解土壤和沉积物等环境基质中令人关注的有机污染物的细菌处理商业化。在第一阶段评估的热增强生物强化技术是基于一种新的细菌菌株及其酶，这些细菌在高温下发挥作用，能够降解各种基于环的有机污染物，包括难以修复的氯化形式。对被总石油碳氢化合物(TPH)污染的土壤的初步测试表明，TPH和环保局优先污染物清单上较重的多环芳烃(PAHs)都有降解作用。第二阶段的目标是通过与在大批量热处理方面拥有丰富经验的成熟环境工程公司合作，将这些初步研究扩大到100s至1000s吨土壤的完全商业规模。为了将这项新技术完全商业化，生物制剂的生产能力也将扩大一个数量级以上。随着过程的发展，这项技术将在异地和现场应用。这一奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。