Glycosaminoglycan-poly (ethylene glycol) hydrogels for improving dermal wound healing (A10)

用于改善真皮伤口愈合的糖胺聚糖-聚乙二醇水凝胶 (A10)

• 批准号: 239909343
• 金额: --
• 依托单位: Institut Biofunktionelle Polymermaterialien
• 依托单位国家: 德国
• 项目类别: CRC/Transregios
• 财政年份: 2013
• 资助国家: 德国
• 起止时间: 2012-12-31 至 2020-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/239909343?language=en
• 关键词: Glycosaminoglycan; poly; ethylene; glycol; hydrogels

C. Werner and U. Freudenberg develop multi-phased hydrogel materials, to combine presentation and sequestration of key signaling molecules of wound healing. At the same time the auto regulative release of bioactive substances from GAG-based polymer networks and the functionalization of the hydrogels with antiseptic and anti-oxidative substances are to be developed. The potential of these multi-phase, interactive biomaterials systems to stimulate cutaneous wound healing, bone regeneration and to modulate morphogenesis will be characterized.

C. Werner和U.弗罗伊登贝格开发多相水凝胶材料，将伤口愈合的关键信号分子的联合收割机呈现和隔离结合起来。同时，生物活性物质从基于GAG的聚合物网络的自动调节释放以及具有防腐剂和抗氧化物质的水凝胶的功能化有待开发。这些多相，相互作用的生物材料系统的潜力，刺激皮肤伤口愈合，骨再生和调节形态发生的特点。