LEAP-HI/GOALI: DfAM of Smart Materials Using a Machine Learning Approach
LEAP-HI/GOALI: DfAM of Smart Materials Using a Machine Learning Approach
批准号:
1953259
负责人:
Mary Frecker
金额:
$50.0万
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
2020
资助国家:
美国
项目状态:
已结题
起止时间:
2020-09-01 至 2023-02-28
中文摘要
点击翻译按钮获取中文摘要
英文摘要
This Leading Engineering for America's Prosperity, Health, and Infrastructure (LEAP-HI) / Grant Opportunity for Academic Liaison with Industry (GOALI) project addresses the complex technical challenge of automated design and additive manufacturing (AM) of customized smart materials and devices. Additive manufacturing, or 3D printing, is a layer-wise approach to manufacturing that is rapidly becoming a viable method for large scale production. The medical device industry, in particular, stands to benefit from AM through manufacture of customizable devices for particular patients, diseases, and/or stages of healing. The project advances AM by developing the ability to print “smart” materials that can change shape in response to external stimuli. The technical challenges are motivated by a medical device industry need identified by the industrial partner, Actuated Medical Incorporated (AMI), for patient-specific adaptive devices that are capable of actively changing their shape at periodic intervals as the patient’s needs change. The active polymer materials developed as part of the project are printed in a single AM process and will provide customized multifunctional devices with fully integrated actuation to advance the state of the art in patient-specific medical devices.The intellectual merit of the researched work resides in the convergence of distinct, yet related and mutually beneficial, areas: smart materials, design, additive manufacturing, and industrial scale-up and integration. Despite the evolution of AM technologies and the ever-expanding growth of smart materials, including printable ones, few researchers have demonstrated the 3D printing of multifunctional multi-material structures and devices. The project addresses this gap in knowledge through the integration of processing, modeling, design and characterization, and by investigating the complex interactions between multiple foci. The technical contributions are: (1) development of functionally graded thermoset polymers with customized shape memory and magneto-mechanical response capabilities, and (2) development of a novel AM fabrication process that is capable of conformal printing and functional grading of multiple materials. In collaboration with the industrial partner, the investigators will develop appropriate performance and fabrication requirements and scale up the research results through direct involvement of students and faculty at the industry partner’s facility, while accounting for regulatory requirements.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
期刊论文(2)
专著(0)
科研奖励(0)
会议论文
DOI:
10.1016/j.addma.2023.103486
发表时间:
2023-03
期刊:
Additive Manufacturing
影响因子:
11
作者:
[O. Uitz;Rui Leng;Tan Pan;Xiaoyue Zhao;A. Oridate;Carolyn C. Seepersad;Z. Ounaies;M. Frecker]
通讯作者:
O. Uitz;Rui Leng;Tan Pan;Xiaoyue Zhao;A. Oridate;Carolyn C. Seepersad;Z. Ounaies;M. Frecker
Fast, low-energy additive manufacturing of isotropic parts via reactive extrusion
通过反应挤出快速、低能耗地增材制造各向同性零件
DOI:
--
发表时间:
2021
期刊:
Additive manufacturing
影响因子:
11
作者:
[Uitz, Oliver, Koirala, P., Tehrani, M., Seepersad, C.]
通讯作者:
Seepersad, C.
EFRI-ODISSEI: Multi-field Responsive Origami Structures - Advancing the Emerging Frontier of Active Compliant Mechanisms
-
批准号:1240459
-
项目类别:Standard Grant
-
资助金额:$200.0万
-
财政年份:2012
-
负责人:Mary Frecker
-
依托单位:
High-Strength High-Strain Structures Using Ceramic Cellular Contact-Aided Compliant Mechanisms (C3M)
-
批准号:0900368
-
项目类别:Standard Grant
-
资助金额:$62.26万
-
财政年份:2009
-
负责人:Mary Frecker
-
依托单位:
POWRE: Methodology for Design of Compliant Mechanisms with Integrated Smart Materials
-
批准号:9870527
-
项目类别:Standard Grant
-
资助金额:$8.0万
-
财政年份:1998
-
负责人:Mary Frecker
-
依托单位:
国内基金
海外基金
登录
查看更多内容
HPV相关阴茎鳞状细胞癌Ly6G+GBP5hi巨噬细胞通过炎性外泌体介导免疫抑制微环境的作用和机制研究
-
批准号:2026JJ80914
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2026
-
负责人:郭洁
-
依托单位:
基于组蛋白H3K18乳酸化修饰调控TREM2hi巨噬细胞研究心肌梗死后修复机制及温阳振衰颗粒干预作用
-
批准号:2026JJ81883
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2026
-
负责人:欧阳过
-
依托单位:
硫碘循环制氢中HI分解催化剂的中毒机制及抗中毒性能提升研究
-
批准号:QN25E060011
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2025
-
负责人:王丽建
-
依托单位:
基于SMRT Hi-C技术的同源染色体识别与配对机制研究
-
批准号:
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2025
-
负责人:吴凡
-
依托单位:
基于法莫替丁调控的Wnt,信号通路及超高b值非高斯扩散模型探讨HI脑损伤分子机制研究
-
批准号:--
-
项目类别:面上项目
-
资助金额:--
-
批准年份:2024
-
负责人:赵鑫
-
依托单位:
基于单细胞测序解析的Ccl3hi中性粒细胞探讨瓜蒌薤白半夏汤改善心肌缺血再灌注损伤的机制研究
-
批准号:
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2024
-
负责人:
-
依托单位:
靶向Nectin 4的Hi-TCR-T联合放射治
疗用于实体瘤治疗的创新技术研发及临床
应用
-
批准号:
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2024
-
负责人:
-
依托单位:
色氨酸/AHR代谢信号通路活化CXCL10hi巨噬细胞在PD-1抑制剂致心脏损伤中的作用
-
批准号:--
-
项目类别:地区科学基金项目
-
资助金额:--
-
批准年份:2024
-
负责人:罗达亚
-
依托单位:
单细胞测序揭示SPP1hi 间充质干细胞通过
CCL7-CCR2 信号轴靶向 CXCL12hiLy6Chi 巨
噬细胞促进肝脏纤维化机制
-
批准号:Q24C120010
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2024
-
负责人:李远慧
-
依托单位:
基于单细胞Hi-C数据的标准化,分类及荟萃分析
-
批准号:
-
项目类别:省市级项目
-
资助金额:15.0万元
-
批准年份:2024
-
负责人:周彦
-
依托单位: