Growth signaling by the plant peptide phytosulfokine

植物肽植物磺因子的生长信号传导

• 批准号: 241861225
• 负责人: Professorin Dr. Margret Sauter (†)
• 金额: --
• 依托单位: Botanisches Institut und Botanischer Garten
• 依托单位国家: 德国
• 项目类别: Research Grants
• 财政年份: 2013
• 资助国家: 德国
• 起止时间: 2012-12-31 至 2020-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/241861225?language=en
• 关键词: Growth; signaling; plant; peptide; phytosulfokine

Plant growth is regulated by phytohormones and peptide signals. The number of peptides that are identified and shown to regulate gowth and development in plants is steadily increasing. Yet, we know comparatively little about peptide mobility and their mode of action. In this project we will study these aspects using the peptide growth factor phytosulfokine (PSK). We will answer the question if PSK acts locally or can be active as a long-distance signal for instance in root to shoot communication. We know that PSK is perceived at the plant cell surface by a membrane-bound receptor. Recent research in our group indicated that the PSK receptor is part of a nanocluster together with a proton pump, a cation channel, and likely a water channel. These proteins play crucial roles in plant cell growth. Taken together, it appears that PSK signaling activates a proton pump to cause cell wall relaxation, opens a cation channel to increase osmotic potential, and facilitates water influx to actually make the cell expand. However, these are hypotheses that need verification. In this project we will study if and how PSK regulates ion and water translocating membrane proteins to promote plant cell growth.

植物生长受植物激素和肽信号调节。被鉴定并显示调节植物生长和发育的肽的数量正在稳步增加。然而，我们对肽的流动性及其作用模式知之甚少。 在本项目中，我们将使用肽生长因子植物硫因子（PSK）研究这些方面。我们将回答这个问题，如果PSK行为本地或可以作为一个长距离的信号，例如在根到芽通信活跃。我们知道PSK在植物细胞表面被膜结合受体感知。我们小组最近的研究表明，PSK受体与质子泵、阳离子通道以及可能的水通道一起是纳米簇的一部分。这些蛋白质在植物细胞生长中起着至关重要的作用。综上所述，PSK信号似乎激活质子泵以引起细胞壁松弛，打开阳离子通道以增加渗透势，并促进水流入以实际使细胞膨胀。然而，这些都是需要验证的假设。在这个项目中，我们将研究是否以及如何PSK调节离子和水转运膜蛋白，以促进植物细胞生长。