COLLABORATIVE RESEARCH: RoL: The evolution and maintenance of variable species boundaries

合作研究：RoL：可变物种边界的进化和维持

• 批准号: 2012041
• 负责人: Erica Larson
• 金额: $ 150.08万
• 依托单位: University of Denver
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-06-01 至 2025-05-31
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2012041&HistoricalAwards=false
• 关键词: COLLABORATIVE; RESEARCH; RoL; evolution; maintenance

Speciation is the process through which new species are formed and is a fundamental driver of the Earth’s biodiversity. New species are defined by the combination of traits that prevent them from mating with other species. However, these traits are not static – they vary depending on the history of a particular population and across different environments. The researchers will use a combination of field and laboratory-based experiments to identify key traits that define two closely related species and test how those traits vary across space. They will then expand their study to other closely related species to test whether traits that define speciation are predictable across a group of species. The project will test new genome sequencing tools in wild populations, inspiring new areas of research in evolution, behavior, and conservation. It will also contribute to the understanding of how new species arise, how they persist across different environments, and whether comparisons between related species are useful to learn about speciation when applied to a broader group of organisms. Through this project, the researchers will provide critical training to undergraduate, graduate and postdoctoral researchers. The researchers will also develop public citizen science resources to help document species diversity across the Colorado Front Range. These resources will improve undergraduate science curriculum and public science education through meaningful scientific experiences.Classic evolutionary theory assumes that species boundaries are fixed differences between species, but barriers between species vary over different temporal, spatial, ecological, and historical contexts. The extent and consequences of this variation on the evolution and maintenance of species boundaries is largely unknown and has not been studied comprehensively in a single system. The proposed research will connect patterns of population level variation to the origin and maintenance of reproductive barriers across a species complex. It will integrate studies of barrier phenotypes (temporal, habitat, behavioral, fertilization, and postzygotic isolation) with patterns of spatial variation in recombination, hybridization, and selection. The researchers will use replicate hybrid zones of North American field crickets to understand variation in reproductive barriers across different scales of biological diversity—within species, between species across multiple independent contact zones of different ages, and across a species complex with overlapping ranges. Key outcomes will be 1) integration of the ecological, behavioral, and genomic context for variation in species barriers, 2) an empirical test of the role of variable reproductive barriers in maintaining species boundaries, 3) a test of the repeatability of the evolution of reproductive barriers across multiple species pairs, and 4) meaningful research experiences for undergraduate non-STEM majors and the public that will increase public engagement with, and appreciation for, nature and science.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

物种形成是形成新物种的过程，是地球生物多样性的根本驱动力。新物种的定义是防止它们与其他物种交配的特征的组合。然而，这些特征并不是一成不变的--它们随特定人群的历史和不同环境的不同而变化。研究人员将使用现场和基于实验室的实验相结合的方法来识别定义两个密切相关物种的关键特征，并测试这些特征在整个空间中的变化。然后，他们将把研究扩展到其他密切相关的物种，以测试定义物种形成的特征是否可以在一组物种中预测。该项目将在野生种群中测试新的基因组测序工具，激发进化、行为和保护方面的新研究领域。它还将有助于理解新物种是如何产生的，它们如何在不同的环境中持续存在，以及相关物种之间的比较是否有助于了解适用于更广泛的有机体群体的物种形成。通过这个项目，研究人员将为本科生、研究生和博士后研究人员提供关键培训。研究人员还将开发公共公民科学资源，以帮助记录科罗拉多前线范围内的物种多样性。这些资源将通过有意义的科学经验来改进本科科学课程和公共科学教育。经典进化论假设物种边界是物种之间固定的差异，但物种之间的障碍随着时间、空间、生态和历史背景的不同而不同。这种变异对物种边界进化和维持的程度和后果在很大程度上是未知的，也没有在一个单一的系统中进行全面的研究。这项拟议的研究将把种群水平变化的模式与物种复合体中生殖障碍的起源和维持联系起来。它将把障碍表型(时间、栖息地、行为、受精和合子后隔离)的研究与重组、杂交和选择的空间变异模式结合起来。研究人员将使用北美田野蟋蟀的复制杂交区来了解不同生物多样性尺度上生殖障碍的变化--物种内，不同年龄的多个独立接触区的物种之间，以及范围重叠的物种复合体之间。主要成果将是1)整合物种障碍变异的生态、行为和基因组背景，2)对可变生殖障碍在维持物种边界方面的作用进行实证测试，3)测试跨多个物种对生殖障碍进化的重复性，4)为本科非STEM专业的学生和公众提供有意义的研究经验，这些研究经验将增加公众对自然和科学的参与和欣赏。该奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。

项目成果

Stage-specific disruption of X chromosome expression during spermatogenesis in sterile house mouse hybrids.

• DOI: 10.1093/g3journal/jkab407
• 发表时间: 2022-02-04
• 期刊: G3 (Bethesda, Md.)

Quantitative Analyses of Coupling in Hybrid Zones

• DOI: 10.1101/cshperspect.a041434
• 发表时间: 2023-12-01
• 期刊: COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY
• 影响因子: 7.2
• 作者: Firneno Jr，Thomas J.;Semenov，Georgy;Gompert，Zachariah
• 通讯作者: Gompert，Zachariah

Unraveling patterns of disrupted gene expression across a complex tissue.

• DOI: 10.1111/evo.14420
• 发表时间: 2022-03
• 期刊: Evolution; international journal of organic evolution

Molecular Evolution across Mouse Spermatogenesis.

• DOI: 10.1093/molbev/msac023
• 发表时间: 2022-02-03
• 期刊: Molecular biology and evolution
• 影响因子: 10.7
• 作者: Kopania EEK;Larson EL;Callahan C;Keeble S;Good JM
• 通讯作者: Good JM

Genetic divergence among threespine stickleback that differ in nuptial coloration

三刺刺鱼婚后颜色不同的遗传差异

• DOI: 10.1111/jeb.14035
• 发表时间: 2022
• 期刊: Journal of Evolutionary Biology
• 影响因子: 2.1
• 作者: Jenck, Clara S.;Lehto, Whitley R.;Hunnicutt, Kelsie E.;Murphy, Shannon M.;Quinn, Thomas W.;Larson, Erica L.;Tinghitella, Robin M.
• 通讯作者: Tinghitella, Robin M.