Advanced Research Training in Physiology - Integrating Biology Across the Scales

海洋生物实验室（MBL）生理学课程成立于1892年，是世界上最古老、持续运行的生物学课程之一。这个培训课程仍然是一个“黄金标准”，它汇集了来自生命科学许多学科的高素质教师和学生。教师们紧密合作，作为一个有凝聚力的团队来教育初出茅庐的生物学家，他们中的许多人会继续做出自己的突破性发现。MBL生理学课程培养了一个独特的训练环境，使用生物学的细胞，分子和物理原理来理解生物体。该NSF奖将用于将细胞和基因组科学与有机体和进化生物学的原理和实践相结合。教师和学生将结合他们独特的观点来解决生理学问题。通过这样做，将获得对“生命如何运作”的生理原理的更深层次的理解，并将其整合到生物学分支学科中。为了延长学员在MBL的学习时间，MBL生理学课程的讲师将邀请和支持学生团队在他们回到各自的研究小组后继续在一起工作。通过课程结束后的体验，每位参与者都将有机会参与并教育公众关于生命有机体的基本原理，以及与生命科学中新知识和发现的社会重要性相关的知识。/p MBL生理学课程在细胞生物学和物理科学的关键交叉点提供强化培训和研究经验-从分子生物学，遗传学，基因组学到进化生物学。课程以密集的“新兵训练营”开始，届时生物学家、物理学家和所有学生将熟悉细胞解剖学和生理学、制造、生物信息学等前沿技术，同时共同分析大数据集。修订后的MBL生理学课程现在将与其他三门同时进行的暑期课程进行互动，将生理学“带回有机体”，并挑战学生在自然环境中考虑细胞。有意地将生理学、微生物多样性、胚胎学和寄生虫生物学课程的学生聚集在一起，将为生物学子学科横向整合中固有的思想协同和扩展多学科视角提供机会。MBL生理学课程培养了一个多元化的学生群体，特别关注STEM中代表性不足的群体的招募和支持。此外，该课程将通过在学生的家庭机构和科学会议上支持有组织的小组来帮助学生传播技术和概念。该奖项由综合生物系统部和分子与细胞生物科学部共同资助。这个奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持

pFounded in 1892, The Marine Biology Laboratory (MBL) Physiology Course is one of the oldest, continually-running biology courses in the World. This training course remains a "Gold Standard" for bringing together faculty, and students selected from a highly qualified pool, across many disciplines in the life sciences. The instructors work closely as a cohesive team to educate early-career biologists, many of whom go on to make their own ground-breaking discoveries. The MBL Physiology Course fosters a unique training environment that uses cellular, molecular, and physical principles of biology to understand living organisms. This NSF award will be used to integrate cellular and genomic science with principles and practices of organismal and evolutionary biology. Faculty and students will combine their unique perspectives to problem solving in physiology. By so doing, a deeper understanding of the physiological principles of "How Life Works" will be attained and integrated across biological subdisciplines. To extend the learning experience beyond the time that each trainee spends at the MBL, instructors in the MBL Physiology Course will invite and support teams of students to continue to work together after they return to their respective research groups at their home institutions. Through this post-course experience, each participant will have the opportunity to engage and educate the general public regarding fundamental principles of living organisms, related to the societal importance of new knowledge and discovery in the life sciences./p pThe MBL Physiology Course provides intensive training and research experiences at critical intersections of cell biology and physical science - ranging from molecular biology, genetics, genomics, to evolutionary biology. The course begins with an intensive "Boot Camp," when biologists, physicists, and all students become familiar with cutting-edge techniques in cellular anatomy and physiology, fabrication, bioinformatics, while working together to analyze big data sets. The revised MBL Physiology Course will now incorporate interactions with three other concurrent summer courses to bring physiology "back into the organism" and challenge students to consider cells in their natural contexts. Intentionally bringing students together from the Physiology, Microbial Diversity, Embryology, and Biology of Parasites courses will provide opportunities for synergism of ideas and expanded multidisciplinary perspectives inherent in this horizontal integration across biological subdisciplines. The MBL Physiology Course trains a diverse student body, with specific attention given to the recruitment and support of under-represented groups in STEM. In addition, the course will aid students in disseminating techniques and concepts via support of organized groups at the students' home institutions and at scientific conferences./p pThis award is cofunded by the Division of Integrative Organismal Systems and the Division of Molecular and Cellular Biosciences./p pThis award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria./p