Advanced Research Training in Physiology - Integrating Biology Across the Scales

创建于1892年的海洋生物实验室(MBL)生理学课程是世界上最古老的、持续不断的生物学课程之一。这一培训课程仍然是将生命科学许多学科的教师和学生从高素质人才池中挑选出来的“黄金标准”。讲师们密切合作，团结一致，培养职业生涯早期的生物学家，其中许多人后来做出了自己的突破性发现。MBL生理学课程培养了一个独特的培训环境，使用细胞、分子和生物学的物理原理来了解活的有机体。该NSF奖将用于将细胞和基因组科学与有机体和进化生物学的原理和实践相结合。教师和学生将结合他们独特的观点来解决生理学问题。通过这样做，我们将更深入地理解“生命是如何运作的”的生理学原理，并将其整合到生物学各分支学科中。为了延长每个学员在MBL花费的时间之外的学习体验，MBL生理学课程的讲师将邀请和支持学生团队在返回各自的研究小组后继续在各自的机构工作。通过这一课程后的体验，每个参与者都将有机会接触和教育普通公众关于生命有机体的基本原理，与生命科学中新知识和新发现的社会重要性有关。/p p MBL生理学课程在细胞生物学和物理科学的关键交叉点提供强化培训和研究经验-从分子生物学、遗传学、基因组学到进化生物学。本课程从密集的“训练营”开始，生物学家、物理学家和所有学生将熟悉细胞解剖和生理学、制造、生物信息学方面的尖端技术，同时共同分析大数据集。修订后的MBL生理学课程现在将包括与其他三门同时开设的暑期课程的互动，以将生理学带回有机体，并挑战学生在自然环境中考虑细胞。有意将生理学、微生物多样性、胚胎学和寄生虫生物学课程的学生聚集在一起，将为在这种跨生物学分支学科的横向整合中固有的思想协同和扩展多学科视角提供机会。MBL生理学课程培训多样化的学生群体，特别关注STEM中代表性不足群体的招募和支持。此外，本课程将通过在学生的家庭机构和科学会议上通过有组织的小组的支持来帮助学生传播技术和概念。/p p该奖项由综合组织系统部门和分子和细胞生物科学部门共同资助。/p p该奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。/p

pFounded in 1892, The Marine Biology Laboratory (MBL) Physiology Course is one of the oldest, continually-running biology courses in the World. This training course remains a "Gold Standard" for bringing together faculty, and students selected from a highly qualified pool, across many disciplines in the life sciences. The instructors work closely as a cohesive team to educate early-career biologists, many of whom go on to make their own ground-breaking discoveries. The MBL Physiology Course fosters a unique training environment that uses cellular, molecular, and physical principles of biology to understand living organisms. This NSF award will be used to integrate cellular and genomic science with principles and practices of organismal and evolutionary biology. Faculty and students will combine their unique perspectives to problem solving in physiology. By so doing, a deeper understanding of the physiological principles of "How Life Works" will be attained and integrated across biological subdisciplines. To extend the learning experience beyond the time that each trainee spends at the MBL, instructors in the MBL Physiology Course will invite and support teams of students to continue to work together after they return to their respective research groups at their home institutions. Through this post-course experience, each participant will have the opportunity to engage and educate the general public regarding fundamental principles of living organisms, related to the societal importance of new knowledge and discovery in the life sciences./p pThe MBL Physiology Course provides intensive training and research experiences at critical intersections of cell biology and physical science - ranging from molecular biology, genetics, genomics, to evolutionary biology. The course begins with an intensive "Boot Camp," when biologists, physicists, and all students become familiar with cutting-edge techniques in cellular anatomy and physiology, fabrication, bioinformatics, while working together to analyze big data sets. The revised MBL Physiology Course will now incorporate interactions with three other concurrent summer courses to bring physiology "back into the organism" and challenge students to consider cells in their natural contexts. Intentionally bringing students together from the Physiology, Microbial Diversity, Embryology, and Biology of Parasites courses will provide opportunities for synergism of ideas and expanded multidisciplinary perspectives inherent in this horizontal integration across biological subdisciplines. The MBL Physiology Course trains a diverse student body, with specific attention given to the recruitment and support of under-represented groups in STEM. In addition, the course will aid students in disseminating techniques and concepts via support of organized groups at the students' home institutions and at scientific conferences./p pThis award is cofunded by the Division of Integrative Organismal Systems and the Division of Molecular and Cellular Biosciences./p pThis award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria./p