Rolled-Up Microsystems

卷起的微系统

基本信息

批准号：
242694901
负责人：
Professor Dr. Jan Gerrit Korvink
金额：
--
依托单位：
CEA Centre de Saclay
依托单位国家：
德国
项目类别：
Research Grants
财政年份：
2013
资助国家：
德国
起止时间：
2012-12-31 至 2016-12-31
项目状态：
已结题

来源：
https://gepris.dfg.de/gepris/projekt/242694901?language=en
关键词：
Rolled Up Microsystems

项目摘要

The RUM consortium will develop a novel micro-technology approach, based on the self-rolling of thin polymeric films, that will result in an extensive micro-engineering process with a high degree of dimensional and morphological control.The research will be based upon a theoretical prediction of the rolling process for non-trivial geometries and morphologies, as well as for each of the relevant processing steps, and a correlation of the predictions with experimental findings.The RUM consortium will combine self-rolling with functional and metal ink-jetting including subsequent galvano-forming to achieve unique inner-tube decoration with micro-devices. The process development will be focused on novel applications that are enabled by this new approach, and will demonstrate the high potential of the technology.The basis application will be an extensive and when required optically transparent lab-on-a-chip infrastructure that lies on top of rather than embedded in the carrier substrate. The above-surface micro-fluidic networks will be augmented by cell-biological functions requiring smooth non- rectangular micro-tubes and patterned chemical decoration of the inner tube surfaces. Through the use of 2 photon polymerisation, unique 3D herringbone-like chaotic flow mixer structures will be formed which should yield a new fluid dynamic understanding and higher degree of fluidic mixing that currently possible in micromixers.The micro-fluidic channels will contain unique and precisely formed Alderman-Grant nuclear magnetic resonance (NMR) detector structures within the tubes, and connected to passives and micro-coaxial cables, that will enable high resolution NMR spectrum (MRS) and imaging (MRI) capabilities whilst at the same time performing microfluidic-based cell-proliferation studies. The RUM consortium will also develop structures with which to connect the fluidic and radiofrequency devices to the outside world.Taken together, we aim to demonstrate unprecedented precision and parallelization of this novel lab-on-a-chip functionality, and if successful, aim to open up brand new areas of investigation.

朗姆酒联盟将基于薄聚合物膜的自我滚动，将开发一种新型的微技术方法，该方法将导致广泛的微工程过程，并具有高度的维度和形态控制，这项研究将基于对滚动过程的理论预测，用于滚动过程，用于滚动过程，并进行验证范围，以及相关的步骤，以及相关的校正，以及相关的校正，并基于各种各样的步骤。调查结果。朗姆酒联盟将自动滚动与功能性和金属墨水射击相结合，包括随后的galvano形成，以实现与微设备的独特的内管装饰。该工艺开发将集中在这种新方法启用的新颖应用程序上，并将证明技术的高潜力。基本应用将是广泛的，并且在需要时使用光学上透明的实验室基础结构，该实验室基础结构位于载体底物中，而不是嵌入在载体基质中。地表上的微流体网络将通过细胞生物学功能增强，需要光滑的非矩形微管和内部管表面的图案化学装饰。 Through the use of 2 photon polymerisation, unique 3D herringbone-like chaotic flow mixer structures will be formed which should yield a new fluid dynamic understanding and higher degree of fluidic mixing that currently possible in micromixers.The micro-fluidic channels will contain unique and precisely formed Alderman-Grant nuclear magnetic resonance (NMR) detector structures within the tubes, and connected to passives and微分辨率NMR光谱（MRS）和成像（MRI）功能，同时进行基于微流体的细胞增殖研究。朗姆酒联盟还将开发结构，以将流体和辐射频将设备连接到外界。