REU Site: Interactive Biomaterials

REU 网站:互动生物材料

基本信息

  • 批准号:
    2049793
  • 负责人:
  • 金额:
    $ 35.47万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
    Standard Grant
  • 财政年份:
    2021
  • 资助国家:
    美国
  • 起止时间:
    2021-09-01 至 2024-08-31
  • 项目状态:
    已结题

项目摘要

This site is supported by the Department of Defense in partnership with the NSF REU program.NON-TECHNICAL DESCRIPTION: The Interactive Biomaterials Research Experiences for Undergraduates site (REU Site) trains cohorts of students from across the country in state-of-the-art biomaterials research to prepare them for future careers in biomaterials science and engineering. This REU Site (1) engages students in independent, leading-edge biomaterials research projects conducted in multidisciplinary and collaborative laboratory environments; (2) provides mentoring opportunities and network-building experiences to excite participants about the societal impacts of careers available to them following graduate education; (3) prepares students to be effective communicators to public and scientific audiences, and (4) creates a welcoming and diverse training environment that promotes the inclusion of all participants. Complementing training in cutting-edge research techniques, students receive one-on-one mentoring from faculty advisors and graduate student mentors and participate in technical writing workshops and team-building activities. A signature element of the REU Site is its career mentoring initiative for doctoral-level industrial and academic career paths, further emphasizing the importance and benefits of graduate education in STEM disciplines. Students also give regular presentations about their research and deliver a formal presentation at a culminating, university-wide research symposium. The REU Site leadership especially encourages the participation of students with limited research opportunities, women, underrepresented minorities, and disabilities to expand their access to these career-enhancing opportunities. With the support of faculty and graduate student mentors and their peers, students develop and enhance their skills in essential areas such as networking, working in research teams, and communicating orally and technically in various formats. Best practices emerging from this REU Site are broadly disseminated via the web and educational publications to enable replication at other future REU sites.TECHNICAL DETAILS: Biomaterials are increasingly designed to be stimulus-responsive, where their properties can change in a controlled way in response to thermal, chemical, or mechanical stimuli in their environment. These interactions between materials and the biological environment, which occur at atomic, molecular, cellular, microscopic, and macroscopic levels, dictate biomaterials’ performance both in vitro and in vivo. The research projects available to students advance knowledge of these fundamental interactions in areas that include: shape memory and stimulus-responsive polymers, nanoparticle drug delivery, the collective behavior of bacterial biofilms, cell-biomaterial interactions, stem-cell research, biocompatible soft robots, 3D printing of microfluidic devices, and computational modeling of biomaterials. These hypothesis-driven, multidisciplinary research projects draw upon the collective expertise of faculty, and in many cases, foster collaborative research across faculty laboratories, academic departments, and institutions. Faculty mentors are highly qualified to mentor undergraduate students in their laboratories; each has a vast array of modern facilities, equipment, and computational resources at their disposal for training these students in cutting-edge research using analytical and computational techniques. Students develop technical skills and expertise to appreciate the complexity of these interactive biomaterials and understand how to harness these materials for advanced technologies, preparing them to pursue advanced study for careers in various sectors and settings.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
该网站由国防部与NSF REU计划合作支持。非-技术描述:面向本科生的交互式生物材料研究体验网站(REU Site)培训来自全国各地的一批学生进行最先进的生物材料研究,为他们未来在生物材料科学和工程领域的职业生涯做准备。这个REU网站(1)让学生参与在多学科和协作的实验室环境中进行的独立的、尖端的生物材料研究项目;(2)提供指导机会和网络建设经验,使参与者兴奋地了解他们在研究生教育后可获得的职业的社会影响;(3)培养学生成为公众和科学受众的有效沟通者;以及(4)创造一个欢迎和多样化的培训环境,促进所有参与者的参与。作为尖端研究技术培训的补充,学生接受教师顾问和研究生导师的一对一指导,并参加技术写作研讨会和团队建设活动。REU网站的一个标志性元素是其针对博士生水平的工业和学术职业道路的职业指导倡议,进一步强调了STEM学科研究生教育的重要性和好处。学生们也会定期报告他们的研究,并在大学范围内的最终研究研讨会上发表正式报告。REU网站领导层特别鼓励研究机会有限的学生、妇女、代表性不足的少数族裔和残疾人士参与,以扩大他们获得这些促进职业生涯的机会的机会。在教师和研究生导师及其同龄人的支持下,学生发展和提高他们在基本领域的技能,如网络、在研究团队中工作,以及以各种形式进行口头和技术性交流。该REU站点的最佳实践通过网络和教育出版物广泛传播,以便在未来的REU站点复制。技术细节:生物材料越来越多地被设计为对刺激敏感,其中它们的特性可以以受控的方式改变,以响应环境中的热、化学或机械刺激。这些发生在原子、分子、细胞、微观和宏观水平上的材料与生物环境之间的相互作用,决定了生物材料在体外和体内的性能。学生可以使用的研究项目在以下领域提高了这些基本相互作用的知识:形状记忆和刺激响应型聚合物、纳米药物输送、细菌生物膜的集体行为、细胞-生物材料相互作用、干细胞研究、生物兼容软机器人、微流控设备的3D打印以及生物材料的计算建模。这些假设驱动的多学科研究项目利用了教员的集体专业知识,在许多情况下,促进了教员实验室、学术部门和机构之间的协作研究。教师导师非常有资格在他们的实验室指导本科生;每个教师都有大量的现代设施、设备和计算资源可供他们使用,用来培训这些学生使用分析和计算技术进行尖端研究。学生发展技术技能和专业知识,以理解这些互动生物材料的复杂性,并了解如何将这些材料用于先进技术,为他们在不同部门和环境中的职业继续深造做好准备。该奖项反映了NSF的法定使命,并通过使用基金会的智力优势和更广泛的影响审查标准进行评估,被认为值得支持。

项目成果

期刊论文数量(2)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
In vitro and in vivo degradation correlations for polyurethane foams with tunable degradation rates
  • DOI:
    10.1002/jbm.a.37504
  • 发表时间:
    2023-02-08
  • 期刊:
  • 影响因子:
    4.9
  • 作者:
    Vakil,Anand Utpal;Petryk,Natalie Marie;Monroe,Mary Beth Browning
  • 通讯作者:
    Monroe,Mary Beth Browning
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Shikha Nangia其他文献

Protein assembly in crowded membranes: Generating potential energy landscapes
  • DOI:
    10.1016/j.bpj.2023.11.2886
  • 发表时间:
    2024-02-08
  • 期刊:
  • 影响因子:
  • 作者:
    Shikha Nangia
  • 通讯作者:
    Shikha Nangia
Characterizing the hydrophobicity of proteins to predict protein assembly
  • DOI:
    10.1016/j.bpj.2022.11.1118
  • 发表时间:
    2023-02-10
  • 期刊:
  • 影响因子:
  • 作者:
    Jingjing Ji;Shikha Nangia
  • 通讯作者:
    Shikha Nangia
Protein-protein interactions at the tight junctions interface
  • DOI:
    10.1016/j.bpj.2022.11.1686
  • 发表时间:
    2023-02-10
  • 期刊:
  • 影响因子:
  • 作者:
    Shikha Nangia;Nandhini Rajagopal
  • 通讯作者:
    Nandhini Rajagopal
Predicting hydration properties of proteins
  • DOI:
    10.1016/j.bpj.2022.11.2516
  • 发表时间:
    2023-02-10
  • 期刊:
  • 影响因子:
  • 作者:
    Britnie Carpentier;Shikha Nangia
  • 通讯作者:
    Shikha Nangia

Shikha Nangia的其他文献

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{{ truncateString('Shikha Nangia', 18)}}的其他基金

Biophysical Effects of Reversible Lipid Modification of Integral Membrane Proteins
完整膜蛋白可逆脂质修饰的生物物理效应
  • 批准号:
    2221796
  • 财政年份:
    2022
  • 资助金额:
    $ 35.47万
  • 项目类别:
    Standard Grant
Collaborative Research: GCR: Infection-Resisting Resorbable Scaffolds for Engineering Human Tissue
合作研究:GCR:用于工程人体组织的抗感染可吸收支架
  • 批准号:
    2218974
  • 财政年份:
    2022
  • 资助金额:
    $ 35.47万
  • 项目类别:
    Continuing Grant
CAREER:Enabling transport across the blood-brain barrier by engineering thermodynamically favorable pathways
职业:通过设计热力学有利的途径实现跨越血脑屏障的运输
  • 批准号:
    1453312
  • 财政年份:
    2015
  • 资助金额:
    $ 35.47万
  • 项目类别:
    Standard Grant

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  • 项目类别:
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REU 网站:互动系统
  • 批准号:
    1950887
  • 财政年份:
    2020
  • 资助金额:
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  • 批准号:
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  • 批准号:
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REU 网站:探索计算机视觉、可视化、普适计算、严肃游戏和社交网络中以人为中心和与社会相关的交互技术
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