REU Site: Interactive Biomaterials

REU 网站：互动生物材料

• 批准号: 1757749
• 负责人: James Henderson
• 金额: $ 31.89万
• 依托单位: Syracuse University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-05-01 至 2023-04-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1757749&HistoricalAwards=false
• 关键词: REU; Site; Interactive; Biomaterials

NON-TECHNICAL DESCRIPTION: The educational objectives of the Interactive Biomaterials REU Site at Syracuse University are: to train students in leading-edge research techniques through independent biomaterials research projects in a multidisciplinary, collaborative, and open laboratory environment; to provide multifaceted mentoring opportunities and network-building experiences that ultimately increase the likelihood that participants will pursue graduate education in their chosen discipline; and to train students to be effective communicators of their research to their peers and the scientific community. These objectives are accomplished through participation in independent, interactive biomaterials research projects in faculty laboratories, one-on-one mentoring from faculty advisors and graduate student mentors, an innovative career mentoring program, student research presentations, team building activities, and social events. The REU Site aims to engage undergraduate students in meaningful and stimulating research and educational and social experiences as a means of increasing their enthusiasm and preparation for future graduate level study and careers in biomaterials science and engineering. TECHNICAL DESCRIPTION: The research projects available to students in the REU will advance fundamental scientific knowledge in areas that include shape memory polymers, stimulus-responsive polymers, drug delivery, control of bacterial biofilms, cell-biomaterial interactions, tissue engineering, and molecular modeling of interactive biomaterials. These hypothesis-driven, multidisciplinary research projects draw upon the collective expertise of the faculty of the Syracuse Biomaterials Institute, and, in many cases, foster collaborative research across faculty laboratories, academic departments, and institutions. Distinguishing characteristics and contributions of the Interactive Biomaterials REU Site include: an educational experience that starts with efficient and effective team building and then centers on research projects appropriate to the undergraduate but sufficiently challenging to allow for students to make meaningful contributions for which they are trained to clearly communicate to diverse technical or lay audiences and readerships; a research environment that provides world class multidisciplinary laboratory facilities and diverse projects and mentors from across three participating institutions who are trained and continually supported by the REU Site leadership throughout the program; a student recruitment and selection process that yields diverse cohorts carefully matched to projects and faculty mentors to maximize the educational experience of the students; and rich and diverse integrated professional development activities designed to support and launch the students' professional goals without distracting from the fundamental research experience.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

非技术描述：互动生物材料REU网站在锡拉丘兹大学的教育目标是：通过在多学科，协作和开放的实验室环境中独立的生物材料研究项目，培养学生领先的研究技术;提供多方面的指导机会和网络建设的经验，最终增加参与者将在他们选择的学科进行研究生教育的可能性;并培养学生成为他们的研究，他们的同行和科学界的有效沟通者。这些目标是通过参与教师实验室的独立，互动的生物材料研究项目，教师顾问和研究生导师的一对一指导，创新的职业指导计划，学生研究报告，团队建设活动和社会活动来实现的。REU网站旨在让本科生参与有意义和刺激的研究，教育和社会经验，以提高他们的热情，为未来的研究生水平的学习和职业生涯做准备，在生物材料科学和工程。 技术说明：REU学生可获得的研究项目将推进基础科学知识，包括形状记忆聚合物，刺激响应聚合物，药物输送，细菌生物膜控制，细胞生物材料相互作用，组织工程和交互式生物材料的分子建模。这些假设驱动的多学科研究项目利用了锡拉丘兹生物材料研究所教师的集体专业知识，在许多情况下，促进了跨教师实验室，学术部门和机构的合作研究。交互式生物材料REU网站的突出特点和贡献包括：从高效和有效的团队建设开始的教育体验，然后集中在适合本科生的研究项目上，但具有足够的挑战性，允许学生做出有意义的贡献，他们接受培训，清楚地与不同的技术或非专业观众和读者沟通;一个研究环境，提供世界一流的多学科实验室设施和来自三个参与机构的多样化项目和导师，他们在整个计划中接受REU网站领导的培训和持续支持;一个学生招募和选择过程，产生不同的群体精心匹配的项目和教师导师，以最大限度地提高学生的教育经验;该奖项反映了NSF的法定使命，并通过使用基金会的智力价值和更广泛的影响审查标准进行评估，被认为值得支持。

项目成果

Interactions of a Polypeptide with a Protein Nanopore Under Crowding Conditions

• DOI: 10.1021/acsnano.9b00008
• 发表时间: 2019-04-01
• 期刊: ACS NANO
• 影响因子: 17.1
• 作者: Larimi, Motahareh Ghahari;Mayse, Lauren Ashley;Movileanu, Liviu
• 通讯作者: Movileanu, Liviu

Anisotropy links cell shapes to tissue flow during convergent extension

• DOI: 10.1073/pnas.1916418117
• 发表时间: 2020-06-16
• 期刊: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
• 影响因子: 11.1
• 作者: Wang, Xun;Merkel, Matthias;Kasza, Karen E.
• 通讯作者: Kasza, Karen E.

Linear and nonlinear mechanical responses can be quite different in models for biological tissues

生物组织模型中的线性和非线性机械响应可能有很大不同

• DOI: 10.1039/c9sm01068h
• 发表时间: 2020
• 期刊: Soft Matter
• 影响因子: 3.4
• 作者: Sahu, Preeti;Kang, Janice;Erdemci-Tandogan, Gonca;Manning, M. Lisa
• 通讯作者: Manning, M. Lisa

Development of the computational antibiotic screening platform (CLASP) to aid in the discovery of new antibiotics

• DOI: 10.1039/d0sm02035d
• 发表时间: 2021-03-14
• 期刊: SOFT MATTER
• 影响因子: 3.4
• 作者: Dai, Yinghui;Ma, Huilin;Nangia, Shikha
• 通讯作者: Nangia, Shikha

In vitro and in vivo degradation correlations for polyurethane foams with tunable degradation rates

• DOI: 10.1002/jbm.a.37504
• 发表时间: 2023-02-08
• 期刊: JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
• 影响因子: 4.9
• 作者: Vakil，Anand Utpal;Petryk，Natalie Marie;Monroe，Mary Beth Browning
• 通讯作者: Monroe，Mary Beth Browning