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EVOLUTIONARY CONFLICT AND PHENOTYPIC DIVERSITY IN SOCIETIES

社会的进化冲突和表型多样性

基本信息

批准号：
2105033
负责人：
Michael Goodisman
金额：
$ 108万
依托单位：
Georgia Tech Research Corporation
依托单位国家：
美国
项目类别：
Continuing Grant
财政年份：
2021
资助国家：
美国
起止时间：
2021-09-01 至 2025-08-31
项目状态：
未结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=2105033&HistoricalAwards=false
关键词：
EVOLUTIONARY CONFLICT PHENOTYPIC DIVERSITY SOCIETIES

项目摘要

Biological organisms display remarkable diversity in form and function. For example, individuals frequently belong to distinct functional classes, such as the male and female sexes. However, because individuals within species generally possess the same set of genes, the development of distinct classes is expected to be constrained. The goal of this research is to study the constraints on the development of distinct classes in social insects. Social insects represent excellent study systems because insect societies are composed of distinct functional classes such as the queen, worker, and male castes. In addition, social insects, such as bees, wasps, ants, and termites, have great ecological and economic importance. This research will analyze the physical forms, gene functions, and genome sequences of social insects to understand the importance of the shared genome on the development of distinct classes. The research will also include several broader impacts that will extend the influence of this research to educational activities aimed at training and educating the public. This research is significant because it will provide insight into the genetic mechanisms associated with the development of distinct functional classes and the causes of organismal diversity within species. Phenotypic diversity is a hallmark of metazoan taxa. However, phenotypic evolution is constrained by intralocus conflict, which occurs when individuals within species possess traits that have a common genetic architecture. This research will explore intralocus conflict in social insects and determine if conflict has constrained phenotypic evolution in societies. Study of genetic conflict in societies is particularly interesting because individuals may experience both intralocus caste conflict, which occurs between the castes, as well as intralocus sexual conflict, which occurs between the sexes. This research will test intralocus conflict theory. First, the research team will determine genetic correlations for morphological traits in queens, males, and workers. Second, intralocus conflict will be studied at the molecular level by testing predictions about genetic correlations for gene expression phenotypes. Finally, evidence for intralocus conflict will be detected by examining population genomic variation. This program will also promote teaching, training, and learning. Research will be incorporated into university classes, city-wide activities, and disseminated in the popular media. Overall, this research program will result in one of the most thorough empirical investigations of intralocus conflict theory and provide insight into the mechanisms affecting phenotypic diversity.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

生物有机体在形态和功能上表现出显著的多样性。例如，个体经常属于不同的功能类别，如男性和女性。然而，由于物种内的个体通常拥有相同的基因组，不同类别的发展预计将受到限制。本研究的目的是研究社会性昆虫中不同类别发展的限制因素。社会性昆虫代表了优秀的研究系统，因为昆虫社会是由不同的功能类，如女王，工人和男性种姓。此外，社会性昆虫，如蜜蜂、黄蜂、蚂蚁和白蚁，具有重要的生态和经济意义。本研究将分析社会性昆虫的物理形态，基因功能和基因组序列，以了解共享基因组对不同类别发展的重要性。这项研究还将包括几个更广泛的影响，将扩大这项研究的影响，以教育活动，旨在培训和教育公众。这项研究意义重大，因为它将深入了解与不同功能类别的发展相关的遗传机制以及物种内生物多样性的原因。表型多样性是后生动物类群的一个标志。然而，表型进化受到基因座内冲突的限制，这种冲突发生在物种内的个体拥有具有共同遗传结构的特征时。这项研究将探讨社会性昆虫的基因座内冲突，并确定冲突是否限制了社会的表型进化。研究社会中的遗传冲突特别有趣，因为个人可能会经历种姓间的种姓内冲突，以及性别间的性冲突。本研究将检验轨迹内冲突理论。首先，研究小组将确定蚁后、雄蚁和工蚁形态特征的遗传相关性。第二，基因座内冲突将在分子水平上通过测试基因表达表型的遗传相关性的预测来研究。最后，基因座内冲突的证据将通过检查群体基因组变异来检测。该方案还将促进教学、培训和学习。研究将被纳入大学课程，全市范围的活动，并在大众媒体传播。总的来说，这项研究计划将导致最彻底的基因座内冲突理论的实证调查之一，并提供深入了解影响表型多样性的机制。该奖项反映了NSF的法定使命，并已被认为是值得通过使用基金会的智力价值和更广泛的影响审查标准进行评估的支持。