Doctoral Dissertation Research: The shape of hands and feet and the transition to upright walking

博士论文研究：手脚的形状以及直立行走的过渡

• 批准号: 2316552
• 负责人: Douglas Boyer
• 金额: $ 3.42万
• 依托单位: Duke University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-08-01 至 2024-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2316552&HistoricalAwards=false
• 关键词: Doctoral; Dissertation; Research; shape; hands

Researchers have long hypothesized that the transition to upright walking on two legs (bipedalism) in humans was facilitated in our distant, non-primate ancestors by an increased reliance on the hind limb while walking on four legs. As a pivotal part of our evolutionary trajectory, it is proposed that once our ancestors’ hands were freed from involvement in walking, they were able to be used for other purposes such as tool use, grooming, and carrying. Previous research on the transition to upright walking in human ancestors has largely focused on non-human primates. To better understand whether the relationship between reliance on hind limbs while walking on four legs and the emergence of bipedalism is unique to human evolution, this doctoral dissertation research project casts a broad comparative net and includes a comparison between primates and carnivores. This project offers opportunities for undergraduate students to gain exposure to STEM-discipline focused ideas and research questions, and to receive transferable technical training and experience.This project tests the hypothesis that the development of a dominant limb is associated with morphological and functional diversification of the non-dominant limb. This project tests this and related hypotheses in three ways: (1) testing if increased reliance on the hind limb allows for diversification of the forelimb by tracking co-variation of hand and foot bones across an expansive sample of extant primate taxa; (2) assessing the effect of limb dominance on functional diversity in an independent mammalian clade (Carnivora) that is thought not to have been characterized by hind limb dominance during its early evolution; and (3) conducting a large-scale comparison of primate and mammalian carnivoran hand and foot bones to track rates of shape variation across both orders. Understanding the ways that the bones of the hands and feet of these groups have evolved helps to elucidate a better understanding of the underlying processes that took place in primates millions of years ago shaping the trajectory of modern human evolution. The broad perspective used in this study is innovative and informative for better understanding of the evolution of bipedalism in humans.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

长期以来，研究人员一直假设，人类向两条腿直立行走（两足行走）的转变在我们遥远的非灵长类祖先中是通过四条腿行走时对后肢的依赖增加而促进的。作为我们进化轨迹的一个关键部分，有人提出，一旦我们祖先的手从行走中解放出来，它们就能够用于其他目的，如工具使用，梳理和携带。以前关于人类祖先向直立行走过渡的研究主要集中在非人类灵长类动物上。为了更好地了解人类在四条腿行走时对后肢的依赖与两足动物的出现之间的关系是否是人类进化所独有的，这个博士论文研究项目构建了一个广泛的比较网络，包括灵长类动物和食肉动物之间的比较。该项目为本科生提供了接触STEM学科重点思想和研究问题的机会，并获得可转移的技术培训和经验。该项目测试了优势肢体的发展与非优势肢体的形态和功能多样化相关的假设。该项目以三种方式测试这一假设和相关假设：（1）通过跟踪现存灵长类动物分类群的广泛样本中手骨和脚骨的共变，测试对后肢的依赖增加是否允许前肢多样化;（2）在一个独立的哺乳动物分支中评估肢体优势对功能多样性的影响（3）对灵长类和哺乳类食肉动物的手骨和足骨进行大规模比较，以跟踪两个目的形状变化率。了解这些群体的手和脚的骨骼进化方式有助于更好地理解数百万年前灵长类动物中发生的塑造现代人类进化轨迹的潜在过程。这项研究中使用的广泛视角是创新的，为更好地了解人类两足行走的演变提供了信息。该奖项反映了NSF的法定使命，并被认为值得通过使用基金会的智力价值和更广泛的影响审查标准进行评估来支持。