Novel approaches for catalyst recycling in organocatalysis

有机催化中催化剂回收的新方法

• 批准号: 263491208
• 负责人: Professor Dr. Udo Kragl
• 金额: --
• 依托单位: Lehrstuhl für Technische Chemie
• 依托单位国家: 德国
• 项目类别: Research Grants
• 财政年份: 2014
• 资助国家: 德国
• 起止时间: 2013-12-31 至 2020-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/263491208?language=en
• 关键词: Novel; approaches; catalyst; recycling; organocatalysis

A significant disadvantage of organocatalysis so far is the use of high catalyst loadings between 1 and 30 mol% to obtain high selectivities and productivities. Within the first funding project period this drawback has been overcome by catalyst recycling as well as simple work up and product isolation with the development of three efficient catalyst recycling concepts. However, these enabling techniques are not fully reflected in the field of new catalytic synthetic methods as well as in the field of process engineering. Therefore, in the next project period advanced organocatalytic processes such as photochemical reactions should be combined with these enabling techniques by simultaneous optimization with micro reaction flow chemistry. Apart from the development of new organocatalytic processes and their mechanistic and theoretical understanding also the aspect of process engineering will be included and investigated at an early stage of this project. The main approach for catalyst recycling will be based on switchable solvent systems since the reaction takes place in the homogeneous phase and thereby maintaining the advantages of homogeneous catalysis. Further investigations on polymerized ionic liquids such as diffusion experiments and reactor experiments should be completed.

迄今为止，有机催化的显著缺点是使用1 - 30摩尔%的高催化剂负载量以获得高选择性和生产率。在第一个资助项目期间，通过开发三种有效的催化剂回收概念，催化剂回收以及简单的后处理和产品分离克服了这一缺点。然而，这些使能技术并没有完全反映在新的催化合成方法领域以及在工艺工程领域。因此，在下一个项目期间，光化学反应等先进有机催化过程应通过与微反应流化学同时优化来与这些使能技术相结合。除了开发新的有机催化过程及其机理和理论理解外，过程工程方面也将包括在内，并在该项目的早期阶段进行研究。催化剂回收的主要方法将基于可切换的溶剂系统，因为反应在均相中发生，从而保持均相催化的优点。聚合离子液体的扩散实验、反应器实验等研究工作有待进一步完善。

项目成果

Enzyme Immobilization in Polymerized Ionic Liquids-based Hydrogels for Active and Reusable Biocatalysts

• DOI: 10.1055/s-0037-1610144
• 发表时间: 2018-04-01
• 期刊: SYNOPEN
• 影响因子: 2.5
• 作者: Grollmisch, A.;Kragl, U.;Grosseheilmann, J.
• 通讯作者: Grosseheilmann, J.

Rheological properties of hydrogels based on ionic liquids

• DOI: 10.1016/j.polymertesting.2020.106943
• 发表时间: 2021-01-01
• 期刊: POLYMER TESTING
• 影响因子: 5.1
• 作者: Jastram, A.;Claus, J.;Kragl, U.
• 通讯作者: Kragl, U.