Do pancreatic stellate cells play a role in pancreatic exocrine secretion?

胰腺星状细胞在胰腺外分泌分泌中发挥作用吗？

• 批准号: DP0772223
• 负责人: Prof Minoti Apte
• 金额: $ 18.25万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2007
• 资助国家: 澳大利亚
• 起止时间: 2007-01-01 至 2009-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0772223
• 关键词: Do; pancreatic; stellate; cells; play

3 major national benefits: 1)Alignment with research priority goals of preventative health care and ageing well ageing productively. Elucidation of mechanisms of action of CCK and the interaction of PSCs and acinar cells in mediating pancreatic secretion will help refine our approach to the prevention and treatment of disorders related to the above processes viz. maldigestion, malabsorption, obesity and pancreatic cancer. 2)Enhancement of Australia's reputation in gastrointestinal (GI) research through a unique collaboration between internationally recognised researchers in GI and pancreatic biology. 3)Training opportunities for Australian research students and scientists in physiology, gastroenterology and pancreatology.

3大国家利益：1）与预防性保健和老龄化的研究优先目标保持一致。阐明CCK的作用机制以及PSC和腺泡细胞在介导胰腺分泌中的相互作用将有助于完善我们预防和治疗与上述过程相关的疾病的方法，即消化不良、吸收不良、肥胖和胰腺癌。2)通过国际公认的GI和胰腺生物学研究人员之间的独特合作，提高澳大利亚在胃肠道（GI）研究方面的声誉。3)为澳大利亚研究生和科学家提供生理学、胃肠病学和胰腺病学方面的培训机会。