Development and Evaluation of Well-Defined Polymer-RNA Conjugates as Improved Therapeutics

明确的聚合物-RNA 缀合物作为改进疗法的开发和评估

• 批准号: DP0770818
• 负责人: Prof Thomas Davis
• 金额: $ 35.11万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2007
• 资助国家: 澳大利亚
• 起止时间: 2007-01-29 至 2011-01-28
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0770818
• 关键词: Development; Evaluation; Well; Defined; Polymer

Gene-based drugs offer an enormous potential to treat a wide range of diseases including, but not limited to, AIDS, hepatitis, and cancer. However, effective delivery of these drugs in body is needed to convert their therapeutic potential to clinically applicable treatments. Our multidisciplinary team will aim to develop novel, polymer-gene hybrid materials for efficient delivery of gene based therapeutics. Development of such advanced drug delivery systems will significantly enhance Australia`s power in biotechnology. Development and/or formation of new materials and strategies to improve the health quality of Australians, is an important anticipated outcome of this innovative project.

基于基因的药物提供了治疗多种疾病的巨大潜力，包括但不限于艾滋病、肝炎和癌症。然而，需要这些药物在体内的有效递送才能将其治疗潜力转化为临床应用的治疗方法。我们的多学科团队将致力于开发新型聚合物基因杂交材料，以有效地提供基于基因的治疗方法。开发这种先进的药物输送系统将大大提高澳大利亚在生物技术方面的实力。开发和/或形成新的材料和战略，以提高澳大利亚人的健康质量，是这一创新项目的一个重要预期成果。