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Understanding the role of caspase-2 in cellular stress response and ageing

Understanding the role of caspase-2 in cellular stress response and ageing
了解 caspase-2 在细胞应激反应和衰老中的作用
批准号:
nhmrc : 1021456
负责人:
Prof Sharad Kumar
金额:
$61.25万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2012
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2012-01-01 至 2016-12-31

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中文摘要
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英文摘要
This project builds upon our recent findings showing that a protein, called caspase-2, is involved in protecting against oxidative damage and ageing in a mouse model. We propose to carry out further studies to fully understand how caspase-2 regulates cell’s response to oxidative stress. Such studies will be critical in assessing if caspase-2 or its substrates are useful targets for drugs to treat diseases that may arise due to cell’s inability to properly respond to oxidative damage.
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New mechanisms regulating the biogenesis of extracellular vesicles
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    DP240101427
  • 项目类别:
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  • 资助金额:
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  • 财政年份:
    2024
  • 负责人:
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Regulation of autophagy dependent cell and tissue deletion
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Cell death by self-eating: Autophagy-dependent tissue removal
  • 批准号:
    DP170100623
  • 项目类别:
    Discovery Projects
  • 资助金额:
    $28.34万
  • 财政年份:
    2017
  • 负责人:
    Prof Sharad Kumar
  • 依托单位:
Regulation of cell death, cell survival and ubiquitination in normal physiology and disease
  • 批准号:
    nhmrc : GNT1103006
  • 项目类别:
    Research Fellowships
  • 资助金额:
    $85.2万
  • 财政年份:
    2016
  • 负责人:
    Prof Sharad Kumar
  • 依托单位:
国内基金
海外基金
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  • 批准号:
    82371070
  • 项目类别:
    面上项目
  • 资助金额:
    49.00万元
  • 批准年份:
    2023
  • 负责人:
    赵培泉
  • 依托单位: