Understanding the role of caspase-2 in cellular stress response and ageing
Understanding the role of caspase-2 in cellular stress response and ageing
批准号:
nhmrc : 1021456
负责人:
Prof Sharad Kumar
金额:
$61.25万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2012
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2012-01-01 至 2016-12-31
中文摘要
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英文摘要
This project builds upon our recent findings showing that a protein, called caspase-2, is involved in protecting against oxidative damage and ageing in a mouse model. We propose to carry out further studies to fully understand how caspase-2 regulates cell’s response to oxidative stress. Such studies will be critical in assessing if caspase-2 or its substrates are useful targets for drugs to treat diseases that may arise due to cell’s inability to properly respond to oxidative damage.
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财政年份:2010
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Regulation of cell death and proliferation by histone demethylases
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依托单位:
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依托单位:
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批准号:nhmrc : 399300
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依托单位:
Temporal and spatial regulation of caspases in development and metamorphosis
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依托单位:
Characterisation of putative targets of the ubiquitin-protein ligase, Nedd4
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Molecular regulation of programmed cell death
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依托单位:
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