Cell death by self-eating: Autophagy-dependent tissue removal
Cell death by self-eating: Autophagy-dependent tissue removal
批准号:
DP170100623
负责人:
Prof Sharad Kumar
金额:
$28.34万
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2017
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2017-01-13 至 2019-12-31
中文摘要
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英文摘要
This project aims to study the mechanisms and regulation of autophagy-dependent cell death. Cell death maintains cell and tissue homeostasis. Although most cell death is mediated by apoptosis, other modes of cell deletion have emerged recently. One form of cell death involves autophagy, the catabolic process of cellular self-digestion through lysosomal enzymes. As autophagy is a default mechanism of cell survival under stress, the idea of autophagy-dependent cell death has been controversial. This proposal aims to resolve this question and provide highly topical knowledge of broad biological significance.
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会议论文
New mechanisms regulating the biogenesis of extracellular vesicles
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批准号:DP240101427
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项目类别:Discovery Projects
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资助金额:$45.52万
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财政年份:2024
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负责人:Prof Sharad Kumar
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依托单位:
Regulation of autophagy dependent cell and tissue deletion
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批准号:DP210100665
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项目类别:Discovery Projects
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资助金额:$35.34万
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财政年份:2021
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负责人:Prof Sharad Kumar
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Regulation of cell death, cell survival and ubiquitination in normal physiology and disease
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批准号:nhmrc : GNT1103006
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项目类别:Research Fellowships
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资助金额:$85.2万
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财政年份:2016
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负责人:Prof Sharad Kumar
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依托单位:
Regulation of cell death, cell survival and ubiquitination in normal physiology and disease
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批准号:nhmrc : 1103006
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项目类别:Research Fellowships
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资助金额:$58.74万
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财政年份:2016
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负责人:Prof Sharad Kumar
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依托单位:
A novel mechanism for regulating membrane proteins by ubiquitin ligases and their adaptors
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批准号:nhmrc : 1059393
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项目类别:Project Grants
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资助金额:$41.87万
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财政年份:2014
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负责人:Prof Sharad Kumar
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依托单位:
Autophagy and growth signalling in developmentally programmed cell death
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批准号:nhmrc : 1041807
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项目类别:Project Grants
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资助金额:$39.62万
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财政年份:2013
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负责人:Prof Sharad Kumar
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依托单位:
Understanding the role of caspase-2 in cellular stress response and ageing
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批准号:nhmrc : 1021456
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项目类别:Project Grants
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资助金额:$61.25万
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财政年份:2012
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负责人:Prof Sharad Kumar
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依托单位:
Physiological function of Nedd4-2 in regulating the epithelial sodium channel and cystic fibrosis transmembrane conductance regulator
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批准号:nhmrc : 1020755
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项目类别:Project Grants
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资助金额:$63.32万
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财政年份:2012
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负责人:Prof Sharad Kumar
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依托单位:
Regulation of cell death, cell survival and ubiquitination in normal physiology and disease
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批准号:nhmrc : 1002863
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项目类别:Research Fellowships
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资助金额:$54.88万
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财政年份:2011
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负责人:Prof Sharad Kumar
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依托单位:
Characterisation of the tumour suppressor function of caspase-2
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批准号:nhmrc : 626905
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项目类别:NHMRC Project Grants
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资助金额:$40.35万
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财政年份:2010
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负责人:Prof Sharad Kumar
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依托单位:
Regulation of cell death and proliferation by histone demethylases
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批准号:nhmrc : 626903
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项目类别:NHMRC Project Grants
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资助金额:$34.75万
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财政年份:2010
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负责人:Prof Sharad Kumar
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依托单位:
Roles of Ndfip1 and Ndfip2 as adaptors for the Nedd4 family of ubiquitin ligases
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批准号:nhmrc : 508085
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项目类别:NHMRC Project Grants
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资助金额:$43.77万
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财政年份:2008
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负责人:Prof Sharad Kumar
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依托单位:
Caspase-2 function in cell death and disease
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批准号:nhmrc : 453482
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项目类别:NHMRC Project Grants
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资助金额:$35.31万
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财政年份:2007
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负责人:Prof Sharad Kumar
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依托单位:
Caspase function in animal development
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批准号:nhmrc : 399302
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项目类别:NHMRC Project Grants
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资助金额:$45.59万
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财政年份:2006
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负责人:Prof Sharad Kumar
-
依托单位:
Research Fellowship - Grant ID:399300
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批准号:nhmrc : 399300
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项目类别:NHMRC Research Fellowships
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资助金额:$50.09万
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财政年份:2006
-
负责人:Prof Sharad Kumar
-
依托单位:
Temporal and spatial regulation of caspases in development and metamorphosis
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批准号:nhmrc : 250349
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项目类别:NHMRC Project Grants
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资助金额:$31.56万
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财政年份:2003
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负责人:Prof Sharad Kumar
-
依托单位:
Characterisation of putative targets of the ubiquitin-protein ligase, Nedd4
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批准号:nhmrc : 157921
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项目类别:NHMRC Project Grants
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资助金额:$17.21万
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财政年份:2001
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负责人:Prof Sharad Kumar
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依托单位:
Molecular regulation of programmed cell death
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批准号:nhmrc : 158068
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项目类别:NHMRC Research Fellowships
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资助金额:$40.47万
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财政年份:2001
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负责人:Prof Sharad Kumar
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依托单位:
Temporal and spatial regulation of caspases in development and metamorphosis
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批准号:nhmrc : 104842
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项目类别:NHMRC Project Grants
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资助金额:$24.61万
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财政年份:2000
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负责人:Prof Sharad Kumar
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依托单位:
Molecular Regulation of Programmed Cell Death
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批准号:nhmrc : 990178
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项目类别:NHMRC Project Grants
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资助金额:$12.83万
-
财政年份:1999
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负责人:Prof Sharad Kumar
-
依托单位:
国内基金
海外基金
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