Functional organization of posterior parietal cortex during multimodal sensory based decisions in the freely moving animal (D05*)

运动动物多模态感觉决策过程中后顶叶皮层的功能组织（D05*）

• 批准号: 388053210
• 金额: --
• 依托单位: Max-Planck-Institut für Neurobiologie des Verhaltens - caesar
• 依托单位国家: 德国
• 项目类别: Collaborative Research Centres
• 财政年份: 2017
• 资助国家: 德国
• 起止时间: 2016-12-31 至 2020-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/388053210?language=en
• 关键词: Functional; organization; posterior; parietal; cortex

The central focus of this project is the posterior parietal cortex, a brain area that receives afferent projections from primary somatosensory and visual cortices. It is thought to be involved in decision making based on visual information, but also in tasks involving spatial navigation. The project will use two-photon Ca2+ imaging with head-mounted miniaturized multiphoton microscope in rats to assess the activity of neuronal populations in the PPC, as they are performing a variety of behavioral tasks designed to test the different functions of the PPC. The project will reveal some of the central principles of organization of the neuronal circuits underlying the function of the PPC in navigational and sensory decision-making tasks.

这个项目的中心焦点是后顶叶皮层，这是一个接受来自初级躯体感觉和视觉皮层的传入投射的大脑区域。它被认为参与基于视觉信息的决策，但也参与涉及空间导航的任务。该项目将使用双光子Ca2+成像和头戴式微型多光子显微镜在大鼠中评估PPC中神经元群体的活动，因为它们正在执行旨在测试PPC不同功能的各种行为任务。该项目将揭示PPC在导航和感觉决策任务中的功能背后的神经元回路组织的一些核心原则。