Development of the new measurement method using the time resolved spectroscopy for the acute abdominal disease

使用时间分辨光谱法开发急腹症新测量方法

• 批准号: 23659848
• 负责人: KAKIHANA Yasuyuki
• 金额: $ 2.25万
• 依托单位: Kagoshima University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Challenging Exploratory Research
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-23659848/
• 关键词: 時間分解分光システム; 近赤外線分光法; 腹部急性疾患; 腸管虚血; 肝酸素化状態; 非侵襲的モニタリング; 時間分解分光法; 酸素化型ヘモグロビン; 脱酸素化型ヘモグロビン; 肝臓; 腸管; 虚血; 低酸素症

The purpose of this study is the development of the new measurement using the time-resolved spectroscopy (TRS) for the acute abdominal disease. The Hb concentration and tissue oxygenation in the liver and intestinal tracts were monitored by the TRS, which probes put on a surface of the body and fixedit, during reduction of FIO2 or cardiac arrest in the pig model. An operation was performed next and a shade board was inserted between the abdominal wall and liver, intestinal tracts, and similar experiments (reduction of FIO2 or cardiac arrest) were carried out. I was able to confirm that the tissue oxygenation in the liver and intestinal tracts could be measured noninvasively by the new measurement using TRS from a surface of a body.

本研究的目的是发展一种新的时间分辨光谱（TRS）测量急腹症的方法。在猪模型中，在FIO2减少或心脏骤停期间，通过TRS监测肝脏和肠道中的Hb浓度和组织氧合，TRS将探针置于身体表面并固定。接下来进行手术，在腹壁和肝脏、肠道之间插入遮光板，并进行类似的实验（FIO2减少或心脏骤停）。我能够证实，肝脏和肠道中的组织氧合可以通过使用来自身体表面的TRS的新测量来非侵入性地测量。