Paternal effects: Non-genetic inheritance via seminal fluid?

父系效应：通过精液非遗传性遗传？

• 批准号: DP160100797
• 负责人: Prof Leigh Simmons
• 金额: $ 36.26万
• 依托单位: The University of Western Australia
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP160100797
• 关键词: Paternal; effects; Non; genetic; inheritance

This project seeks to improve understanding of the mechanisms of non-genetic inheritance and its ability to promote adaptation. Although offspring are known to resemble their parents through the action of genes, there is now a growing awareness of non-genetic mechanisms by which parents can affect the growth and health of their offspring. This project aims to quantify the putative role of seminal fluid in so-called non-genetic inheritance. Using an insect model, the project aims to identify proteins in the seminal fluid that promote early embryo development, explore how males allocate these proteins to their mates, and how females adjust their own reproduction in response to seminal fluid proteins. Improving knowledge of these mechanisms may enable the development of interventions to control the unwanted evolution of harmful organisms.

该项目旨在提高对非遗传机制及其促进适应能力的认识。虽然后代通过基因的作用而与父母相似，但现在人们越来越认识到父母可以影响后代的生长和健康的非遗传机制。该项目旨在量化精液在所谓的非遗传中的假定作用。利用昆虫模型，该项目旨在确定精液中促进早期胚胎发育的蛋白质，探索雄性如何将这些蛋白质分配给配偶，以及雌性如何调整自己的生殖以应对精液蛋白质。提高对这些机制的认识可能有助于制定干预措施，以控制有害生物的有害进化。