Study of Golgi pH sensor and the mechanism for the localization

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（1）As an important clue to identify a Golgi pH sensor or its downstream factor, protein A whose overexpression corrects the mutant phenotypes such as delayed transport and impaired glycosylation, and protein B whose overexpression cancels the normalizing effect of protein A, were identified by expression cloning.（2）Impaired complex formation of glycosyltranferases but not their mis-localization in the Golgi seemed one of the mechanisms for impaired glycosylation.