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Modern reptiles with ancient toxins: the molecular origin and evolution of novel bioactive proteins from squamate dental glands.

Modern reptiles with ancient toxins: the molecular origin and evolution of novel bioactive proteins from squamate dental glands.
具有古老毒素的现代爬行动物:鳞状牙腺新型生物活性蛋白的分子起源和进化。
批准号:
DP0665971
负责人:
Prof Bryan Fry
金额:
$9.98万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2006
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2006-01-01 至 2008-12-31

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中文摘要
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英文摘要
Animal venoms provide a rich source of novel bioactive proteins, some of which have demonstrated therapeutically useful activities. Through this researcher's unique approach of investigating previously unmapped squamate venom systems, there is potential for the identification of divergent, bioactive proteins. Those already identified by the applicant in the dental glands of Australian monitor lizard species represent a tremendous opportunity for biodiscovery. Further knowledge in this area will increase medical understandings of bites and aid conservation measures informed by the natural history of these animals.
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