Why is lacticin Qa super-bacteriocin ?
Why is lacticin Qa super-bacteriocin ?
批准号:
23658081
负责人:
SONOMOTO Kenji
金额:
$2.58万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012
中文摘要
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英文摘要
Lacticin Q, a lactococcal pore (Huge Toroidal Pore)-forming bacteriocin, shows activity toward Gram-positive bacteria but not Gram-negative bacteria. Lacticin Q did not induce permeability of the outer membrane of Gram-negative bacteria. Experiments using model membranes containing outer membrane components suggested that lacticin Q binds to the outer membrane of Gram-negative bacteria but isunable to penetrate it. The lack of activity of lacticin Q was attributed to physicochemical features of the outer membrane components.
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乳酸菌バクテリオシン-戦略的な探索・発見・活用とゼロエミッションPJまで-
乳酸菌细菌素-战略性探索、发现、利用及零排放项目-
DOI:
--
发表时间:
2011
期刊:
日本乳酸菌学会誌
影响因子:
--
作者:
[石橋直樹, 善藤威史, 園元謙二]
通讯作者:
園元謙二
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[齋藤忠夫, 伊藤裕之, 岩附慧二, 吉岡俊満編, 井沢真吾, Yasushi Kawai and Tadao Saito, 井沢真吾分担執筆, Yasushi Kawai and Tadao Saito]
通讯作者:
Yasushi Kawai and Tadao Saito
乳酸菌バクテリオシン-戦略的な探索・発見・活用とゼロエミッションPJまで-
乳酸菌细菌素-战略性探索、发现、利用及零排放项目-
DOI:
--
发表时间:
2011
期刊:
日本乳酸菌学会誌
影响因子:
--
作者:
[S.Koyama, et al, 石橋直樹,善藤威史,園元謙二]
通讯作者:
石橋直樹,善藤威史,園元謙二
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[S.Koyama, et al, 石橋直樹,善藤威史,園元謙二, Kenji Sonomoto]
通讯作者:
Kenji Sonomoto
DOI:
10.1128/aac.00808-10
发表时间:
2011-01
期刊:
Antimicrobial Agents and Chemotherapy
影响因子:
4.9
作者:
[F. Yoneyama;K. Ohno;Y. Imura;Mengqi Li;T. Zendo;J. Nakayama;K. Matsuzaki;K. Sonomoto]
通讯作者:
F. Yoneyama;K. Ohno;Y. Imura;Mengqi Li;T. Zendo;J. Nakayama;K. Matsuzaki;K. Sonomoto
共 8 条
Structural analysis and functional modification of unusual amino acid-forming enzyme, and the application to peptide engineering
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批准号:26292040
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.73万
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财政年份:2014
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负责人:SONOMOTO Kenji
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依托单位:
Lantibiotic engineering: peptide engineering approach using the modification enzymes
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批准号:23380050
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.06万
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财政年份:2011
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负责人:SONOMOTO Kenji
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依托单位:
Kinetic study and optimization of acetone-butanol-ethanol fermentation by systematic fermentomics
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批准号:19380052
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.73万
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财政年份:2007
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负责人:SONOMOTO Kenji
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依托单位:
HIGH-THROUGHPUT SCREENING OF NOVEL BACTERIOCINS FROM LACTIC ACID BACTERIA AND CONSTRUCTION OF THE FERMENTATION SYSTEM
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批准号:17380054
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.28万
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财政年份:2005
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负责人:SONOMOTO Kenji
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依托单位:
Application of biocatalysts for development of non-natural organosilicon compounds
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批准号:04805102
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.22万
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财政年份:1992
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负责人:SONOMOTO Kenji
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依托单位:
海外基金