Amino acids are pivotal substances in energy metabolism?

氨基酸是能量代谢的关键物质？

• 批准号: 23658174
• 负责人: USHIO Hideki
• 金额: $ 2.33万
• 依托单位: The University of Tokyo
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Challenging Exploratory Research
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-23658174/
• 关键词: アミノ酸; 代謝; 魚類; エネルギー

A rabbit polyclonal antibody against zebrafish GLP-1 was produced and used for the detection of GLP-1 protein in several tissues. The antibody did not work well unfortunately. Lys-deficient diet induced lipid mobilization from liver to muscle, which suggests that amino acids function as pivotal regulators in fish energy metabolisms.

制备了兔抗斑马鱼GLP-1的多克隆抗体，并用于检测几种组织中的GLP-1蛋白。不幸的是，抗体并没有很好地工作。赖氨酸缺乏的饲料诱导脂肪从肝脏向肌肉的转移，这表明氨基酸在鱼类能量代谢中起着关键的调节作用。

项目成果

Comparison in taste and extractive components of boiled dorsal muscle and broth from half-smooth golden puffer Lagocephalus spadiceus caught in Japan with those of the same fish imported

日本捕获的半滑金河豚背肌和肉汤与进口同种鱼的煮背肌和肉汤的味道和提取物成分比较

• DOI: 10.1007/s12562-012-0585-2
• 发表时间: 2013
• 期刊: Fish Sci
• 作者: Hiroko Yamaguchi;Misako Nakaya,Gen Kaneko;Chie Yoneda;Toshitaka Mochizuki,Katsuya Fukami;Hideki Ushio,Shugo Watabe
• 通讯作者: Hideki Ushio,Shugo Watabe

エビ類の遊泳脚および幼生体からのミオシン重鎖遺伝子クローニング

虾游足和幼虫肌球蛋白重链基因克隆

• 发表时间: 2013
• 作者: Karim Honein;Gen Kaneko;MasaoYamada,Engkong Tan;Shuichi Asakawa;Hideki Ushio;五十嵐洋治,木下滋晴,土井啓行,石橋敏章,潮秀樹,渡部終五;大西愛美,小山寛喜,木下滋晴,金子元,浅川修一,室井洋佑,宮崎誠尚,渡部終五,潮秀樹;小山寛喜,Sanit Piyapattanakorn,潮秀樹,安元剛,神保充,渡部終五
• 通讯作者: 小山寛喜,Sanit Piyapattanakorn,潮秀樹,安元剛,神保充,渡部終五

cDNA cloning, gene expression and nutritional regulation of the hormone sensitive lipase genes inred seabream (Pagrus major)

真鲷激素敏感脂肪酶基因的 cDNA 克隆、基因表达及营养调控

• 发表时间: 2012
• 作者: Anurak Khieokhajonkhet;Gen Kaneko;Lu Wang;Muhammad Mehedi Hasan;Shugo Watabe and Hideki Ushio
• 通讯作者: Shugo Watabe and Hideki Ushio

Linear chain aldehydes evoke calcium responses in B16 melanoma cells

直链醛在 B16 黑色素瘤细胞中引起钙反应

• 发表时间: 2011
• 期刊: EXCLI J
• 影响因子: 4.6
• 作者: Ishikawa Y;Ohara K;Ohshima T;Ushio H
• 通讯作者: Ushio H

Oxidized arachidonic acid and hexanal enhance mouse taste perception of monosodium glutamate

氧化花生四烯酸和己醛增强小鼠对味精的味觉感知

• 发表时间: 2013
• 期刊: Nutritional Neuroscience
• 影响因子: 3.6
• 作者: Susumu Yamaguchi;Hidenori Fujiwara;Ikukazu Tashima;Hideki Ushio
• 通讯作者: Hideki Ushio