From proton to deuteron relaxometry: The next generation of field-cycling NMR relaxometers

从质子到氘核弛豫测量：下一代场循环核磁共振弛豫测量

• 批准号: 407261664
• 负责人: Professor Dr. Ernst Rößler
• 金额: --
• 依托单位: Institut für Physik Kondensierter Materie (IPKM)
• 依托单位国家: 德国
• 项目类别: New Instrumentation for Research
• 财政年份: 2019
• 资助国家: 德国
• 起止时间: 2018-12-31 至 2021-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/407261664?language=en
• 关键词: proton; deuteron; relaxometry; next; generation

By applying the field-cycling (FC) technique, NMR relaxometry has made a big step forward providing access to the frequency dependence of the spin-lattice relaxation in all kinds of soft matter. The frequency dependence directly reflects the molecular dynamics. Most FC studies focus on protons. Due to the multi-particle character of the relevant interaction a super-position of molecular reorientation and translation is probed, which often hampers quantitative insights. In contrast, deuteron FC NMR solely detects reorientation and, hence, theoretical understanding and computer simulation are strongly facilitated. One also profits from the isotope selectivity of NMR which allows data to be interpreted in a much more specific way as compared to other methods. However, as the deuteron NMR frequency is small, current FC relaxometers are not suitable for routine FC NMR studies. Rather, a new generation of relaxometers has to be developed. A combination of quickly switching thousands of amperes in a sophistically designed coil system and reaching a strong magnetic field of high accuracy make the task very demanding. It is the aim of the present project to achieve this and to make deuteron FC NMR a routine technique of “molecular rheology”. Likewise, investigations of other nuclei such as 7Li, 13C, and 31P will become possible, and even proton relaxometry will strongly benefit.

通过应用场循环(FC)技术，核磁共振弛豫测量向前迈进了一大步，它提供了各种软物质中自旋-晶格弛豫的频率依赖关系。频率依赖性直接反映了分子动力学。大多数FC研究都集中在质子上。由于相关相互作用的多粒子特性，分子重定向和平移的叠加被探讨，这往往阻碍了对定量的洞察。相比之下，氚核磁共振只检测重新取向，因此，理论理解和计算机模拟是非常方便的。人们还受益于核磁共振的同位素选择性，与其他方法相比，它允许以更具体的方式解释数据。然而，由于氢核磁共振的频率很小，目前的FC弛豫仪不适合常规的FC核磁共振研究。相反，必须开发新一代弛豫计。在精心设计的线圈系统中快速切换数千安培和达到高精度的强磁场相结合，使任务变得非常苛刻。本项目的目标是实现这一点，并使氘FC核磁共振成为一种常规的“分子流变学”技术。同样，对7Li、13C和31P等其他原子核的研究也将成为可能，甚至质子弛豫法也将大有裨益。