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Physiological Studies on the Functional Alteration During Growth of Domestic Animals with Special Reference to Environments.

家畜生长过程中功能变化的生理学研究，特别涉及环境。

基本信息

批准号：
01480091
负责人：
SUGANO Shigeru
金额：
$ 0.9万
依托单位：
The University of Tokyo
依托单位国家：
日本
项目类别：
Grant-in-Aid for General Scientific Research (B)
财政年份：
1989
资助国家：
日本
起止时间：
1989 至 1990
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-01480091/
关键词：
Growth Autonomic nerve Behavior Heart rate Horse Functional development Pig Goat

项目摘要

1. Alterations of behaviors and autonomic nervous tone in response to visual stimulus with a silhouette of a real size of horse were compared between pregnant and non-pregnant horses. The similar experiment was performed in Shiba-goats. The behavioral reaction was characterized as more nervous or alarming in pregnant animals than in non-pregnant animals. Analysis of heart rate and wave form (T-wave) of electrocardiogram suggested the prevailing sympathetic nervous tone in pregnant animals as compared with non-pregnant animals.2. Alterations of the heart rate with and without autonomic blockade were traced through the growing period in rats and pigs. The parasympathetic tone of rats was low at 2 weeks of age and became higher during 2 to 4 weeks, whereas that of piglets at 2 weeks of age was highest at 2 weeks of age. In piglets, the net autonomic tone, expressed as a sum of the sympathetic and the parasympathetic tones, was maintained at the sympathetic side through the experimental period.3. Cardiovascular functions (heart rate, femoral arterial pressure, right and left intraventricular pressure, left intraventricular dP/dt, aortic flow and stroke volume) before and after autonomic blockade were studied in piglets between 2 and 12 weeks of age. The intrinsic cardiovascular function of piglets during the growth process was regulated sympathetically in all the parameters except for stroke volume, which might be regulated autonomically through the Frank-Starling mechanism rather than autonomic nervous system.4. The clear relationship was recognized between the growth and the litter size, sex constitution of sucklings or experience of parturition, based upon the analysis of past records on growth in pigs and Shiba-goats, and also experiments with rats.

1.比较了怀孕和非怀孕马对真实的马的轮廓视觉刺激的行为和自主神经张力的变化。在柴山羊中进行了类似的实验。妊娠动物的行为反应比非妊娠动物更紧张或惊恐。心率和心电图波形（T波）分析表明，妊娠动物与非妊娠动物相比，交感神经紧张占优势.在大鼠和猪的生长期追踪了有和没有自主神经阻滞的心率变化。大鼠的副交感神经张力在2周龄时较低，在2至4周龄期间变得较高，而仔猪在2周龄时的副交感神经张力在2周龄时最高。在仔猪中，净自主神经张力，表示为交感神经和副交感神经张力的总和，在整个实验期间维持在交感神经侧。研究了2 ~ 12周龄仔猪自主神经阻滞前后的心血管功能（心率、股动脉压、右心室和左心室内压、左心室内dP/dt、主动脉流量和每搏输出量）。在生长过程中，仔猪心血管的内在功能除每搏输出量外，其他参数均受交感神经系统的调节，其调节机制可能是Frank-Starling机制，而不是自主神经系统.通过对猪和芝山羊生长记录的分析，以及对大鼠的实验，明确了生长与窝仔数、哺乳动物性别构成和分娩经验之间的关系。