Cochlear blood flow in sudden deafness

耳蜗血流量受损可能是突发性耳聋的病理生理因素之一。对9例疑似外淋巴瘘的突发性耳聋患者进行了耳蜗血流量测定。在探查性鼓室切开术中，激光多普勒探头的尖端附着在圆窗壁龛前部附近的海角上。增加了激发光纤和接收光纤之间的距离，以提高最大深度灵敏度。在所有9例患者中，观察到与心电图相对应的激光输出的脉动。我们试图测量二氧化碳对耳蜗血流量的影响，例如吸入二氧化碳和停止呼吸。然而，在大多数情况下，这些手术并没有观察到耳蜗血流量的显著变化。

Impairment of cochlear blood flow may be one of the factors implicated in the pathophysiology of sudden deafness. Cochlear blood flow in sudden deafness was measured in nine patients who were suspected of having perilymphatic fistulas. During exploratory tympanotomy, the tip of a laser-Doppler probe was attached to the promontory near the anterior portion of the round window niche. The distance between the exciting and receiving optic fibers was increased to elevate the maximum depth sensitivity. In all nine patients, pulsatory movement of the laser output that corresponded to ECG was observed. We attempted to measure effects of carbon dioxide on cochlear blood flow, such as inhalation of carbogen and cessation of respiration. In almost cases, however, no significant change of cochlear blood flow was observed by these procedures.