Computer-Aided Diagnosis System in Chest Radiography

胸部X线计算机辅助诊断系统

• 批准号: 06454326
• 负责人: KATSURAGAWA Shigehiko
• 金额: $ 2.3万
• 依托单位: Iwate Medical University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (B)
• 财政年份: 1994
• 资助国家: 日本
• 起止时间: 1994 至 1995
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-06454326/
• 关键词: Computer-Aided Diagnosis; Digital Radiography; Image Database; Chest Radiograph; Digital Image Processing; 胸部肺疾患

We have developed a system and schemes of computer-aided diagnosis (CAD) for detection of nodules, interstitial diseases, pneumothorax and cardiomegaly in digital chest radiograph.1. The CAD system hardware was established, which includes a film-digitizer, a workstation, a laser-imager, a video-printer and a personal computer.2. The image-difference method was developed for detection of lung nodules. The performance with approximately 75% of the sensitivity at 1.0 false positive/image was provided for 100 normal and 100 abnormal lungs with lung nodules.3. The texture and geometric feature analyzes were developed for detection of interstitial diseases. The performance with approximately 95% of the sensitivity at 95% of the specificity was provided for 100 normal and 100 abnormal lungs with interstitial infiltrates.4. The method with Hough transform was developed for detection of pneumothorax. 80% sensitivity at 70% specificity was provided for 60 lungs with pneumothorax.5. The method based on a model function was developed for measurement of size and shape of hearts.6. The ROC analysis showed that the diagnostic accuracy with both chest images and CAD outputs was superior to that with chest images alone for detection of nodules and interstitial diseases.7. Our results indicates that this computer-aided diagnosis system is very useful for radiologists to estimate chest radiographs.

我们已经开发了一个系统和方案的计算机辅助诊断（CAD）检测结节，间质性疾病，气胸和心脏扩大的数字胸片。建立了CAD系统硬件，包括胶片数字化仪、工作站、激光成像仪、视频打印机和个人计算机.提出了一种基于图像差分的肺结节检测方法。对100个正常肺和100个有肺结节的异常肺，在1.0个假阳性/图像时，其灵敏度约为75%.纹理和几何特征分析被开发用于检测间质性疾病。对100例正常肺和100例异常肺间质浸润的诊断灵敏度和特异度分别为95%和95%。提出了一种基于Hough变换的气胸检测方法。对60个气胸肺的敏感性为80%，特异性为70%。提出了一种基于模型函数的心脏尺寸和形状测量方法. ROC分析显示，对于结节和间质性疾病的检测，胸部图像和CAD输出的诊断准确性优于单独使用胸部图像的诊断准确性上级.我们的研究结果表明，这个计算机辅助诊断系统是非常有用的放射科医生估计胸片。

项目成果

J. Morishita: "Computer-aided diagnosis for interstitial infiltrates in chest radiographs: Analysis of optical-density dependence on texture measures." Medical Physics. 22. 1515-1522 (1995)

J. Morishita：“胸片中间质浸润的计算机辅助诊断：光密度对纹理测量的依赖性分析。”

桂川茂彦: "胸部単純X線写真におけるコンピュータ支援診断" 日本医学放射線物理学会雑誌. (印刷中).

桂川茂彦：“胸部平片的计算机辅助诊断”日本医学放射物理学会杂志（正在出版）。

J. Morishita: "Computer-aided diagnosis for interstitial infiltrates in chest radiographs : Analysis of optical-density dependence on texture measures." Medical Rhysics. 22. 1515-1522 (1995)

J. Morishita：“胸片中间质浸润的计算机辅助诊断：分析光密度对纹理测量的依赖性。”

桂川茂彦: "医用X線像のコンピュータ診断" シュプリンカー・フェアラーク東京, 269 (1994)

桂川茂彦：“医学 X 射线图像的计算机诊断”Sprinker Verlag Tokyo，269（1994）

桂川茂彦: "胸部疾患におけるCAD" 日本医学放射線物理学会雑誌. 15. 113-121 (1995)

Shigehiko Katsurakawa：“胸部疾病中的 CAD”日本医学放射物理学会杂志 15. 113-121 (1995)。