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Study of the original and treatment of strabismus by EMG.

斜视的病因及治疗的肌电图研究。

基本信息

批准号：
62480365
负责人：
TAMURA Osamu
金额：
$ 2.5万
依托单位：
Ehime University
依托单位国家：
日本
项目类别：
Grant-in-Aid for General Scientific Research (B)
财政年份：
1987
资助国家：
日本
起止时间：
1987 至 1989
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-62480365/
关键词：
esotropia exotropia visually evoked cortical potential electro myo graphy proprioception of the ocular muscles 斜視 Magician's Forceps現象伸張反射

项目摘要

We have reported that the pathogenesis of strabismus is closely related to proprioceptive afferents. And it is supposed that the development of strabismus is under the influence of the visual input In this study, we demonstrated the proprioceptive afferent and visual input were cooperative for the developmental mechanism of strabismus. Cases studied here were esotropic patients aged from one year and two months to seven years and exotropic ones aged from fifteen to sixty two years. Visually evoked cortical potentials to flash stimulation (VECP) and electromyograph (EMG) were examined. Recordings of VECP were made from two electrodes located at O_2 and O_2. Monocular stimulation of each eye and binocular stimulation were used and the flash stimuli were projected to all visual fields of retina. EMGs of four horizontal rectal muscles were recorded either under general anesthesia for esotropic patients of children or in conscious patients with exotropia.In cases with esotropia, there was no difference in amplitude from both 0_1, and O_2 in binocular VECP. But in monocular VECP, we found the reduced amplitude. of contralateral VECP as compared with that of ipsilateral VECP. While all esotropic patients showed abnormal discharges in EMG, there was no difference in EMG in the patients with the disparities of amplitudes in monocular VECP. In exotropic patients we found no difference in monocular VECP and abnormal discharges in EMG. We suppose the mechanism of proprioception in exotropia affects the decussating optic system and that in esotropia acts on the non-decussating optic system. Because strabismus changes to be orthophorized under the light of less than 0.6 lux, the proprioceptive afferents might be In effect without visual input.Since some patients with esotropia showed the reduced amplitude of contralateral VECP monocularly stimulated, there may be a disorganization of devussated optic nerve fibers in esotropia.

我们已经报道斜视的发病机制与本体感觉传入密切相关。斜视的发生是在视觉输入的影响下进行的。本研究证实了本体感觉传入和视觉输入在斜视发生中的协同作用。研究对象为内斜视患者，年龄1岁2个月~ 7岁，外斜视患者，年龄15 ~ 62岁。检查闪光刺激视觉诱发皮层电位（VECP）和肌电图（EMG）。VECP由位于O_2和O_2的两个电极记录。采用单眼刺激和双眼刺激，闪光刺激投射到视网膜的所有视野。对内斜视儿童和清醒的外斜视儿童分别在全麻下记录了4条直肠水平肌的肌电图，内斜视者双眼VECP的0_1、O_2波幅无明显差异。但在单眼VECP中，我们发现振幅降低。对侧VECP与同侧VECP比较。所有内斜视患者的肌电图均出现异常放电，但单眼VECP波幅差异患者的肌电图无差异。在外斜视患者中，我们发现单眼VECP和EMG异常放电无差异。我们认为，外斜视的本体感觉作用于交叉视系统，而内斜视的本体感觉作用于非交叉视系统。由于在0.6lux以下的光线下，斜视变为正斜视，本体感觉传入可能在没有视觉输入的情况下无效，而部分内斜视患者单眼刺激对侧VECP时，其波幅降低，可能存在内斜视时视神经纤维的紊乱。