The fundamental and clinical studies of proprioception of the ocular muscles.

眼肌本体感觉的基础和临床研究。

• 批准号: 63304049
• 负责人: TAMURA Osamu
• 金额: $ 8.77万
• 依托单位: EHIME UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Co-operative Research (A)
• 财政年份: 1988
• 资助国家: 日本
• 起止时间: 1988 至 1989
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-63304049/
• 关键词: proprioception; muscle spindle; trigeminal nerve; 斜視; 眼球運動

An attempt to solve a nature of proprioception of the ocular muscles is the aim of the present investigation.Mukuno compared diameter and distribution of neural cells of trigeminal nerve supplying the medial rectus muscle with the ciliary body in the trigeminal ganglion. The differences in distribution were not shown. However, Peaks in histogram showed smaller in diameters of cells supplying the ciliary body and larger in it.Shimo-oku examined mediating time from the trigeminal ganglion to the abducens ganglion. In the pathway from trigeminal ganglion to abducens ganglion, it was supposed that the pathway had polysynapse.Ito solved that second messengers and protein kinase C participated in a transduction and encoding processes in mechainoreceptors.Ito and Mukuno observed muscle spindles of pathologic ocular muscles and found the passing and permanent change of the internal structure of muscle spindles.Takahasi measured visual acuities, double vision tests, "Visual fields, stereo vision tests, corneal sensations, eye position tests, electro-oculo grams, optokinetic nystagmus tests, forced duction tests and magician's forceps tests on the patients in cerebral hemorrhage, demielination and herpes zester ophthalmicus. Relationship between proprioceptiv impulse and accommodation spasm, normal ocular movement.Tsutsui treated squints with poturinusu toxin. From results of the treatment, exodeviations were divided in convergence insufficiency type and divergence excess type. From results of pastpointing tests, it is suggested that toxic effect on the gamma neurons were week.Tamura recorded the eye movement using electro-oculogram after blocking the trigeminal ganglion, and phasedefference was found on movement of the blocked side eye.

试图解决眼肌本体感觉的本质是本研究的目的。Mukuno比较了三叉神经节中支配内侧直肌和睫状体的三叉神经神经细胞的直径和分布。分布上的差异没有显示出来。直方图峰显示睫状体细胞直径较小，睫状体细胞直径较大。Shimo-oku检查了从三叉神经节到外展神经节的调节时间。在三叉神经节到外展神经节的通路中，认为该通路存在多突触。Ito认为第二信使和蛋白激酶C参与了机械受体的转导和编码过程。Ito和Mukuno对病理性眼肌的肌梭进行了观察，发现肌梭的内部结构发生了短暂和永久性的变化。高桥对脑出血、脱色、眼疱疹患者进行了视敏度测量、复视试验、视野、立体视觉试验、角膜感觉、眼位试验、眼电图、眼球震颤试验、强迫诱导试验和魔术师钳试验。本体感觉冲动与调节痉挛、正常眼动的关系。Tsutsui用poturinusu毒素治疗斜视。根据治疗结果，将外偏分为收敛不足型和发散过剩型。从过去的点状实验结果来看，提示其对γ神经元的毒性作用是周的。Tamura阻断三叉神经节后用眼电图记录眼球运动，发现被阻断侧眼的运动有相位差。