The fundamental and clinical studies of proprioception of the ocular muscles.

眼肌本体感觉的基础和临床研究。

• 批准号: 63304049
• 负责人: TAMURA Osamu
• 金额: $ 8.77万
• 依托单位: EHIME UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Co-operative Research (A)
• 财政年份: 1988
• 资助国家: 日本
• 起止时间: 1988 至 1989
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-63304049/
• 关键词: proprioception; muscle spindle; trigeminal nerve; 斜視; 眼球運動

An attempt to solve a nature of proprioception of the ocular muscles is the aim of the present investigation.Mukuno compared diameter and distribution of neural cells of trigeminal nerve supplying the medial rectus muscle with the ciliary body in the trigeminal ganglion. The differences in distribution were not shown. However, Peaks in histogram showed smaller in diameters of cells supplying the ciliary body and larger in it.Shimo-oku examined mediating time from the trigeminal ganglion to the abducens ganglion. In the pathway from trigeminal ganglion to abducens ganglion, it was supposed that the pathway had polysynapse.Ito solved that second messengers and protein kinase C participated in a transduction and encoding processes in mechainoreceptors.Ito and Mukuno observed muscle spindles of pathologic ocular muscles and found the passing and permanent change of the internal structure of muscle spindles.Takahasi measured visual acuities, double vision tests, "Visual fields, stereo vision tests, corneal sensations, eye position tests, electro-oculo grams, optokinetic nystagmus tests, forced duction tests and magician's forceps tests on the patients in cerebral hemorrhage, demielination and herpes zester ophthalmicus. Relationship between proprioceptiv impulse and accommodation spasm, normal ocular movement.Tsutsui treated squints with poturinusu toxin. From results of the treatment, exodeviations were divided in convergence insufficiency type and divergence excess type. From results of pastpointing tests, it is suggested that toxic effect on the gamma neurons were week.Tamura recorded the eye movement using electro-oculogram after blocking the trigeminal ganglion, and phasedefference was found on movement of the blocked side eye.

本研究的目的是试图解决眼肌本体感觉的性质。Mukuno比较了供应内直肌的三叉神经神经的神经细胞的直径和分布与睫状体在三叉神经节。未显示分布差异。直方图显示睫状体供应细胞直径较小，睫状体供应细胞直径较大。Shimo-oku检查了从三叉神经节到外展神经节的介导时间。在三叉神经节到外展神经节的通路中，推测该通路为多突触通路，Ito解决了第二信使和蛋白激酶C参与了机械感受器的信号转导和编码过程，Ito和Mukuno观察了病理性眼肌的肌梭，发现了肌梭内部结构的短暂和永久性改变，Takahasi测量了视力、复视试验、对脑出血、视网膜脱离、眼带状疱疹患者进行视野、立体视觉、角膜感觉、眼位、眼电图、视动性眼球震颤、强迫牵引和魔术钳试验。本体感受性冲动与调节痉挛、正常眼球运动的关系。筒井用波氏毒素治疗斜视。根据治疗结果，外斜视分为会聚不足型和发散过度型。过去指向实验结果表明，对γ神经元的毒性作用较弱。Tamura在阻断三叉神经节后，用眼电图记录了被阻断侧眼的运动，发现其运动存在相位差。