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Study of Sudden Death at Exertion: Refference to Athlete's Heart.

劳累时猝死的研究：对运动员心脏的参考。

基本信息

批准号：
62480444
负责人：
MATSUDA Mitsuo
金额：
$ 4.48万
依托单位：
THE UNIVERSITY OF TSUKUBA
依托单位国家：
日本
项目类别：
Grant-in-Aid for General Scientific Research (B)
财政年份：
1987
资助国家：
日本
起止时间：
1987 至 1988
项目状态：
已结题

项目摘要

To investigate a factor affecting exercise-related sudden cardiac death, we study the relation of left vetricular cavity dilatation (LVCD) or left ventrcular wall hypertrophy (LVWH) in athletes to ventricular arrhythmias and left ventricular funtion.The occurrence rate of ventricuar premature beats (VPB's) during a 5000m time-trial run in 26 male long-distance runners was 23%. LVCD was shown in 31% of the subjects, and LVWH was shown in 23% of the subjects. The ocurence rate of VPB's was higher in the subjects with LVWH than that in the subjects without LVWH, though not statistically significantly. Ventricular ectopic activity might be enhanced in the endurance runners with the hypertrophic left ventricular wall thickened unproportionally, although the further studies in a larger figure of subjects should be recommended.Hemodynamic parameters in 70 male power lifters were estimated during isometric hand grip exercise test. LVWH was revealed in 20% of subjects. The left ventricular systolic and diastolic functions during isometric exercise might be deteriorated to some degree in subjects with LVH, because the augmentation of the cardiac functions during exercise, which was revealed in subjects without LVH, were not shown in subjects with LVH.The occurence rate of VPB's during squats in 45 male power lifters was 24%. and that of LVWH was 16%. LVWH in subjects was mild in this study. There was no significant relation between the degree of LVWH and ventricular ectopic activity, although the further study in the subjects with more significant LVWH should recommended.

为探讨运动性心脏性猝死的影响因素，对26名男子长跑运动员5000 m计时跑中室性早搏（VPB）的发生率为23%，研究了运动员左室腔扩大（LVCD）或左室壁肥厚（LVWH）与室性心律失常及左室功能的关系。31%的受试者显示LVCD，23%的受试者显示LVWH。LVWH组室性早搏发生率高于无LVWH组，但无统计学意义。本文对70名男子力量举重运动员等长握力试验中的血流动力学参数进行了测定。20%的受试者显示LVWH。LVH者在等长运动时左室收缩和舒张功能可能有不同程度的恶化，因为LVH者在运动时心功能增强，而无LVH者则无此现象。45名男子举重运动员蹲起时室性早搏的发生率为24%。LVWH为16%。本研究中受试者的LVWH为轻度。LVWH程度与室性异位活动无明显相关性，但对LVWH程度较重者应进一步研究。