The Induced Resistance of Timothy infected Acremonium Endophyte

蒂莫西感染顶孢霉内生菌的诱导抗性

• 批准号: 04660128
• 负责人: YOSHIHARA Teruhiko
• 金额: $ 1.34万
• 依托单位: Hokkaido University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (C)
• 财政年份: 1992
• 资助国家: 日本
• 起止时间: 1992 至 1993
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-04660128/
• 关键词: Acremonium Endophyte; Timothy; Induced Resistance; Fungitoxic compound; Chkol; Chkolic Acid; Chokolal; チモシーがまの穂病; チョーク; GamahonolideA; GamahonolideB; Gamahorin

Choke disease fungus Epichloe typhina (Pers. ex Fr.) Tul., an endophyte of timothy grass (Phleum prantense L.), is associated with resistance to leaf spot disease (Cladosporium phelei) in timothy grass plants. Timothy chokes, stromata of E.typhina, contain many classes of antifungal compounds. We condidered that the resistance may be associated with the presence of antifungal metabolites which were produced by E.typhina or the host plant, and as a result of interaction between the two organisms.The auther started to isolate biological active compounds and finally isolated 13 sesquiterpens [six chkols(G-L), chkolal A, six chkolic acids (A-D)], three lactons [gamahonolide (A and B) and gamahorin], four lignans, six phytols and two sphingoids. Some of them are new fungitoxic compounds. Phytols stimulated the growth of Cladosporium herbarum.

窒息性疾病真菌Epicheliotyphina（Escherichia ex Fr.）图：梯牧草（Phymothy prantense L.）的内生菌，与梯牧草植物对叶斑病（Cladosporiumphelei）的抗性有关。鼠伤寒沙门氏菌（E.typhina）的子座Timothy chokes含有多种抗真菌化合物。作者从生物活性化合物的分离出发，共分离出13个倍半萜类化合物（6个chkols（G-L），chkolal A，6个chkolic acids（A-D）），3个内酯类化合物（gamahonestrine（A，B），gamahorin），四种木脂素、六种植醇和两种鞘氨醇。其中一些是新的真菌毒性化合物。植醇刺激了草本枝孢菌的生长。

项目成果

H.Koshino: "Gamahonolides A, B and Gamahorin, Novel Antifungal Compounds from Stromata of Epichloe typhina on Phleum pratense" Biosci.Biotech.Biochem.56. 1096-1099 (1992)

H.Koshino：“Gamahonolides A、B 和 Gamahorin，来自 Phleum pratense 上的 Epichloetyphina 基质的新型抗真菌化合物”Biosci.Biotech.Biochem.56。

Hiroyuki Koshino: "Two Sphingoid Derivatives from Stromata of Epichloe typhina on phleum pratense" Phytochemistry. 31. 3757-3759 (1992)

Hiroyuki Koshino：“来自草叶上的火蜥蜴基质的两种鞘氨醇衍生物”植物化学。

H.Koshino: "Two Sphingoid Derivatives from Stromata of Epichloe Typhina on Phleum Pratense" Phytochem.31. 3757-3759 (1992)

H.Koshino：“来自 Phleum Pratense 上 Epichloe Typhina 基质的两种鞘氨醇衍生物”Phytochem.31。

H.Koshino: "Derivatives from Stromata of Epichloe Typhina on Phleum Pratense" Phytochem. 31. 3757-3759 (1992)

H.Koshino：“来自 Phleum Pratense 上的 Epichloe Typhina 子座的衍生物”Phytochem。

H.Koshino: "Gamahonolides A,B and Gamahorin,Novel Antifungal Compounds from Stromata of Epichloe typhina on Phleum pratense" Biosci.Biotech.Biochem.56. 1096-1099 (1992)

H.Koshino：“Gamahonoliides A、B 和 Gamahorin，来自 Phleum pratense 上的 Epichloetyphina 基质的新型抗真菌化合物”Biosci.Biotech.Biochem.56。