The change of general movement in infants with brain damages

脑损伤婴儿全身运动的变化

• 批准号: 04670584
• 负责人: KONISHI Yukuo
• 金额: $ 1.22万
• 依托单位: Fukui Medical School
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (C)
• 财政年份: 1992
• 资助国家: 日本
• 起止时间: 1992 至 1993
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-04670584/
• 关键词: General Movement; Brain Damage; preterm infant; MRI; CT; 自発運動; 姿勢

General movements (GMs) were qualitatively assessed in 6 infants at 36-43 weeks postmenstrual age, who were diagnosed wit brain damage during perinatal period. Neurological examinations and neuro-imaging techniques (US, CT or MRI) were also performed in all cases. The results of GM assessment correlated with the simultaneous findings on neuro-imaging. In patients with severe brain damage in whom MRI revealed brain lesions not only in cerebral hemisphere, but also in the brain stem and spinal cord, there was no GMs. In patients with brain damage demonstrated in only cerebral hemisphere, cramped-synchronized GMs occurred. These findings suggested that interneuronal circuits in the spinal cord are capable of pruducing GMs. The predictive value of GM assessment was found to be similar to that of neuro-imaging, and better than that of neurological examination.

对6例围产期诊断为脑损伤的36~43周龄婴儿的一般运动功能(GM)进行了定性检测。所有病例均进行了神经学检查和神经成像技术(US、CT或MRI)。GM的评估结果与神经影像的同步发现相关。在严重脑损伤的患者中，MRI不仅显示大脑半球的脑损伤，而且还显示脑干和脊髓的损伤，没有GMS。在仅表现为大脑半球脑损伤的患者中，出现了狭小同步的GMS。这些发现表明，脊髓中的神经元间环路能够复制转基因动物。GM评估的预测价值与神经影像相似，但优于神经学检查。

项目成果

Fujii Y.: "MRI assessment of myelination patterns in high-risk infnats." Pediatr.Neurol. 9. 194-197 (1993)

Fujii Y.：“高危婴儿髓鞘形成模式的 MRI 评估。”

Konishi Y.: "Posture of low-risk preterm infants." Proceedings of communications and posters of 2nd world congress of perinatal medicine.921-925 (1993)

Konishi Y.：“低风险早产儿的姿势。”

Yukuo Konishi: "Posture of low-risk preterm infants." Proceedings of Communications and posters of 2nd world congress of perinatal medicine.921-925 (1993)

Yukuo Konishi：“低风险早产儿的姿势。”

Yukuo Konishi: "The development of posture in prone and supine position during prenatal period in low-risk pre-term infants." Arch.Dis.Child.(in press). (1994)

Yukuo Konishi：“低风险早产儿产前俯卧位和仰卧位姿势的发展。”

Yukuo Konishi: "The development of posture in prone and supine position during prenatal period in low-risk preterm infants" Arch.Dis.Child.(in press). (1994)

Yukuo Konishi：“低风险早产儿产前俯卧位和仰卧位姿势的发展”Arch.Dis.Child.（出版中）。