Spontaneous oscillations of the hemoglobin oxygenation in neonates.

点击翻译按钮获取中文摘要

Spontaneous oscillations of the hemoglobin oxygenation state were observed in all the infants. Time series analysis based on the theory of non-linear oscillators showed that the mean periods of the oscillation for each infant ranged from 11 to 18s.Spatially synchronized oscillations of changes in the concentration of oxy- and deoxy- hemoglobin were observed throughout the occipital cortex in the neonates but not in the infants aged 1 month after birth. It was observed that the phase lag of oxy-Hb relative to deoxy-Hb was stable at about 3π/4 in neonates but in the infants aged 1 month, the phase lag was not stable. This phase difference may result from interplay between the vasomotion and the oxygen consumption in relation to brain activity.These findings may be explained by the dynamic morphological and metabolic changes of the visual cortex in early life.