Effect of epidural anesthesia on sympathetic nerve activities.

背景：由流行性焦虑恶化的外围血管和诱导低血压引起的对称性神经阻滞。在未被阻挡的区域内，对称神经活动可能会导致手皮肤温度和脚趾脉冲强度的下降。在猫的未封闭区域，我们测量了直接心脏病（CSNA）和再生神经病活动（RSNA）中的补偿性对称性兴奋，同时在甲状腺（TEA）或肺流行性焦虑（LEA）中测量了在猫。方法：猫分为三个组; TEA组在T4接收的流行病导管中的6只猫，在L1接收的LEA组中的6只猫，LEA+拒绝组中的三只猫在L1跟随的中-aortic和vagal拒绝。心率（HR）、平均气压（MAP）、CSNA和RSNA在30分钟内重复测量了单剂量0.1毫升·千克^<-1> 1%的左旋胆碱。结果：在TEA组， HR减少到91%， MAP减少到87%， CSNA减少到26%，RSNA增加到144%，对照值的100%。在LEA组，人力资源决定为93%， MAP决定为87%，CNA增加为164%，RSNA减少为30%。在LEA+去除组中， HR减少到93%， MAP减少到73%，RSNA减少到42%，但CNA未改变。结论：在未封闭的区域中，与甲状腺或肺结核相关的紧张关系中的符号神经活动。这一对称性兴奋在发生的时候消失了，因为它发生了肺结核流行性焦虑症，发生了一起金黄色和阴道剥夺。对综合性神经的补偿性兴奋的结果从肠梗阻反射到重度焦虑症的诱导。

Background : The sympathetic nerve blockade by epidural anesthesia dilates peripheral vessels and induces hypotension. The sympathetic nerve activity in the unblocked area may induce the fall of hand skin temperature and toe pulse amplitude. To estimate compensatory sympathetic excitation in the unblocked area, we measured directly cardiac(CSNA) and renal sympathetic nerve activities(RSNA) simultaneously during thoracic(TEA) or lumbar epidural anesthesia(LEA) in cats.Methods : The cats were divided into three groups ; 6 cats in the TEA group received an epidural catheter at T4,6 cats in the LEA group at L1, and 3 cats in the LEA plus denervation group at L1 following sino-aortic and vagal denervations. Heart rate(HR), mean arterial pressure(MAP), CSNA, and RSNA were measured repeatedly for 30 min after a single dose of 0.1ml・kg^<-1> of 1% lidocaine via the epidural catheter.Results : In the TEA group, HR decreased to 91%, MAP decreased to 87%, CSNA decreased to 26%, and RSNA increased to 144% from 100% of the control values. In the LEA group, HR decreased to 93%, MAP decreased to 87%, CSNA increased to 164%, and RSNA decreased to 30%. In the LEA plus denervation group, HR decreased to 93%, MAP decreased to 73%, and RSNA decreased to 42%, but CSNA unchanged.Conclusion : The sympathetic nerve activity in the unblocked area increased in relation to hypotension during thoracic or lumbar epidural anesthesia. This sympathetic excitation disappeared during lumbar epidural anesthesia following sino-aortic and vagal denervations. The compensatory excitation of the sympathetic nerves results from the baroreceptor reflex to hypotension induced by epidural anesthesia.