Development of an Oscillating Hung-Vessel Blood Pump

振荡悬挂血管血泵的研制

• 批准号: 05808086
• 负责人: MIYASHITA Osamu
• 金额: $ 1.15万
• 依托单位: Tokyo Denki University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (C)
• 财政年份: 1993
• 资助国家: 日本
• 起止时间: 1993 至 1994
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-05808086/
• 关键词: Blood pump; Centrifugal pump; Thrombus; Hemolysis; Artificial organ; Open heart surgery

The purposes of this research are to construct a new blood pump, which is called an oscillating hung-vessel blood pump, and to investigate its fundamental characteristics. This report gives the following new features :1. An oscillating vessel blood pump with horizontal movement mode was first investigated to obtain fundamental knowledge for the hung-vessel type. It was observed that the horizontal-movement-mode type pump had a maximum output when the flexible membrane slightly touched the vessel's bottom. However, this configuration increases hemolysis. Efforts should be concentrated how to configurate a membrane in the vessel. A improved-membrane vessel pump with 5mm-eccentric has 6L/min output for 80mmHg load at 3000rpm. The blood pump was tested in vitro using bovine blood. Hemolysis was improved ; the index of hemolysis is about 0.09. However, the value is still large for practical use. Problems to smoothen inner surface of a vessel and to reduce mechanical vibrations should be solved.2. Using the knowledge mentioned above, we constructed an oscillating hung-vessel blood pump that is supported by two universal joints. The top-side joint prevents vessel's rotation. The other joint is connected to the eccentric axis. Fundamental characteristic of the pump, pressure head versus flow rate, was evaluated.3. The blood pump is driven by an inverter-fed induction motor from the viewpoint of maintenance free. Various technical problems are discussed. A new control scheme is proposed to improve imput power factor and to reduce harmonics on the mains side.In this research, we discussed fundamentals of the proposed blood pump and its driving system. To improve characteristics of the proposed blood pump it is necessary to investigate various configurations of vessel and membrane, and to make further experiments. These are problems to be solved in the future.

本研究的目的是构造一种新的血泵，称为振荡式血管血泵，并研究其基本特性。该报告提供了以下新功能：1.首先研究了具有水平运动模式的振荡血管血泵，以获得悬挂血管类型的基础知识。观察到当柔性膜稍微接触容器底部时，水平移动模式型泵具有最大输出。然而，这种配置增加了溶血。应该集中精力如何在容器中配置膜。改进的膜式血管泵偏心距为5 mm，在3000 rpm转速下，80 mmHg负荷下的输出流量为6L/min。使用牛血对血泵进行体外测试。溶血现象得到改善，溶血指数约为0.09。然而，对于实际使用来说，价值仍然很大。应解决容器内表面光滑和减少机械振动的问题.利用上述知识，我们构建了一个由两个万向节支撑的振荡血管血泵。顶侧接头可防止船舶旋转。另一个接头连接到偏心轴。对泵的基本特性，压头与流量的关系进行了评价.从免维护的角度来看，血泵由逆变器供电的感应电机驱动。讨论了各种技术问题。提出了一种新的控制方案，以提高输入功率因数和减少电源侧的谐波。为了改善所提出的血泵的特性，有必要研究各种结构的血管和膜，并进行进一步的实验。这些都是今后要解决的问题。

项目成果

O.Miyashita, et al.: ""High Power Factor PWM Rectifiers with an Analog Pulse-Width Predictor"" Proceedings of IEEE Applied Power Electronics Conference. 563-568 (1994)

O.Miyashita 等人：“具有模拟脉冲宽度预测器的高功率因数 PWM 整流器””IEEE 应用电力电子会议论文集。

I.Sakuma, et al.: ""Development of an Oscillating Vessel Blood Pump (The 2nd report)"" Proceedings of The 6th Bioengineering Division Conference. 73-75 (1994)

I.Sakuma 等人：“振荡血管血泵的开发（第 2 次报告）”第 6 届生物工程分部会议论文集。

佐久間一郎: "ロータリー血液ポンプ" BME(日本ME学会雑誌). 7. 14-21 (1993)

Ichiro Sakuma：“旋转式血泵”BME（日本 ME 协会杂志）7. 14-21 (1993)。

佐久間一郎: "揺動型血液ポンプの開発(第二報)(試作ポンプの血球破壊特性)" 第6回バイオエンジニアリング学術講演論文集. (発表予定). (1994)

佐久间一郎：“振荡血泵的开发（第二次报告）（原型泵的血细胞破坏特性）”第六届生物工程学术会议论文集（预定报告）（1994年）。

I.Sakuma, et al.: ""Development of an Oscillating Vessel Blood pump"" Proceedings of The 5th Bioengineering Division Conference. 101-103 (1993)

I.Sakuma 等人：“振荡血管血泵的开发”第五届生物工程分部会议论文集。