Effects of inner ear pathology on the input impedance of the cochlea

内耳病理对耳蜗输入阻抗的影响

• 批准号: 06807134
• 负责人: GYO Kiyofumi
• 金额: $ 1.22万
• 依托单位: Ehime University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (C)
• 财政年份: 1994
• 资助国家: 日本
• 起止时间: 1994 至 1995
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-06807134/
• 关键词: acoustic impedance; stapes mobility; piezoelectric ceramic; inner ear pressure; perilymphatic fistula; laser-doppler intorferometor; 外リンパ痿; アブミ骨固着; 蝸牛窓閉鎖

The effects of inner ear pathology on the input impedance of the cochlea were studied in animals using a laser-doppler interferometer or a piezoelectric ceramic device of our design. In guinea pigs, vibration amplitudes of the umbo were measured before and after either one of the following three procedures ; rupture of the round window membrane, destruction of the cochlea and increase in inner ear pressure. Rupture of the round window membrane caused increase in umbo vibration up to 10 dB in mid-frequencies. Destruction of the cochlea resulted in 10 dB increase in the vibration at all the frequencies. Pressure loading to the inner ear induced the decrease in the vibration at low frequencies and the increase at mid-frequencies. This suggested that the changes in the inner ear impedance can be detected by the vibration mode of the tympanic membrane.Chaine cochlear input impedance were measured uaing a piezoelectric device. It was designed for future use in human subjects during middle ear surgery. The impedance value was 3.9 Megohm at 1 kHz, which gradually increased at higher frequencies.

使用激光多普勒干涉仪或我们设计的压电陶瓷装置研究了内耳病理学对耳蜗输入阻抗的影响。在豚鼠中，在以下三个过程中和之后测量了UMBO的振动幅度。圆形窗户膜破裂，耳蜗破坏并增加内耳压力。圆形窗户膜的破裂导致umbo振动在中间频率中的增加高达10 dB。耳蜗的破坏导致所有频率的振动增加了10 dB。向内耳的压力加载会导致低频下振动的减少，并在中部频率下增加。这表明可以通过鼓膜膜的振动模式检测到内耳阻抗的变化。链的耳蜗输入阻抗是通过压电设备测量的。它设计用于中耳手术期间在人类受试者中的未来使用。阻抗值为1 kHz的3.9 megohm，在较高频率下逐渐增加。

项目成果

西原 信成: "レーザードップラー速度計によるヒト鼓膜振動の測定" Audiology Japan. 38. 631-632 (1995)

Nobunari Nishihara：“使用激光多普勒测速法测量人体鼓膜振动”日本听力学 38. 631-632 (1995)。

Shinsei Nishihara, Takayuki Shinohara, Kiyofumi Gyo: "Human tympanic menbrane vibration measured by use of a laser-doppler interferometer" Audiology Japan. 38. 631-632 (1995)

Shinsei Nishihara、Takayuki Shinohara、Kiyofumi Gyo：“使用激光多普勒干涉仪测量人体鼓膜振动”日本听力学。

西原信成: "レーザードップラー速度計によるヒト鼓膜振動の測定" Audiology Japan. 38. 631-632 (1995)

Nobunari Nishihara：“使用激光多普勒测速仪测量人体鼓膜振动”日本听力学 38. 631-632 (1995)。

暁 清文: "内耳インピーダンス術中測定の試み" Audiology Japan. 38. 639-640 (1995)

Kiyofumi Akatsuki：“术中测量内耳阻抗的试验”日本听力学 38. 639-640 (1995)。

佐藤 英光: "圧電素子を用いた内耳インピーダンスの測定-イヌによる実験的研究" 耳鼻臨床. 88. 1353-1359 (1995)

Hidemitsu Sato：“使用压电元件测量内耳阻抗 - 使用狗进行的实验研究”耳鼻喉科 88. 1353-1359 (1995)