Development of Measurement method of Stapes Mobility

镫骨活动度测量方法的研制

• 批准号: 10557150
• 负责人: KOIKE Takuji
• 金额: $ 3.01万
• 依托单位: TOHOKU UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 1998
• 资助国家: 日本
• 起止时间: 1998 至 1999
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-10557150/
• 关键词: Middle ear; Ossicles; Mobility; Measurement; Transmission factor; Tympanoplasty

It is important to evaluate the stapes mobility in tympanoplasty because it largely affects the degree of the prognostic hearing level. However, the practical objective measurement method of the stapes mobility has not been well established. Within the present study, the sensor was made to measure the displacement and reaction force of the stapes. The stapes mobility of guinea pigs and rabbits with normal and artificially fixed stapes were measured using this sensor, and the objective diagnosis method was discussed. Moreover, an attempt was made to measure the stapes mobility with the sensor held in hand for clinical use. The results could be drawn as follows :1. The reaction force increases linearly in the small displacement region, but nonlinearly in the large displacement region. The stiffnesses of the normal stapes of guinea pigs and rabbits in small displacement region were 16 【minus-plus】 7N/m and 115 【minus-plus】 25N/m, respectively.2. The significant difference was found between the stiffness of the normal and artificially fixed stapes, which as confirmed to be similar to realistic fixation by the CM measurement. These results indicated that this measurement system could be used for diagnosis of the stapes fixation.3. Although the stapes mobility was measured within 0.02 sec with the sensor held in hand, the stiffness curves well agreed with those in static measurement. The measurement of the stapes mobility within 0.02 sec did not be affected by the viscosity of the cochlea and ligament and the hand trembling.After this, a smaller device for clinical use will be made using micromachining technique.

在鼓室成形术中，镫骨活动度的评估是非常重要的，因为它在很大程度上影响着听力水平的预后。然而，镫骨活动度的客观测量方法尚未建立。在本研究中，传感器被用来测量镫骨的位移和反作用力。用该传感器测量了正常和人工固定镫骨的豚鼠和家兔的镫骨活动度，并探讨了镫骨活动度的客观诊断方法。此外，还尝试用手持传感器测量镫骨活动度以供临床使用。结果表明：1.反力在小位移区呈线性增加，而在大位移区呈非线性增加。正常豚鼠和家兔镫骨小位移区的刚度分别为16 [-+] 7 N/m和115 [-+] 25 N/m.发现正常和人工固定的镫骨刚度之间存在显着差异，通过CM测量证实这与实际固定相似。结果表明，该测量系统可用于镫骨固定的诊断.虽然镫骨活动度的测量在0.02秒内与传感器手持，刚度曲线与静态测量结果一致。在0.02秒内测量镫骨活动度不受耳蜗和韧带的粘性和手抖的影响。之后，将使用微机械加工技术制造用于临床的较小装置。