Development of Measurement method of Stapes Mobility

在鼓室成形术中，镫骨活动度的评估非常重要，因为它在很大程度上影响预后听力水平的程度。然而，镫骨迁移率的客观测量方法还没有很好的建立。在本研究中，传感器用于测量镫骨的位移和反作用力。用该传感器测量了正常镫骨和人工固定镫骨的豚鼠和家兔的镫骨活动度，并探讨了客观诊断方法。此外，我们还尝试用手持传感器测量镫骨的活动性，以供临床使用。研究结果如下：1。反力在小位移区呈线性增长，在大位移区呈非线性增长。豚鼠和家兔正常镫骨在小位移区刚度分别为16【负正】7N/m和115【负正】25N/m。正常镫骨与人工固定镫骨的刚度存在显著差异，经CM测量证实与实际固定相似。结果表明，该测量系统可用于镫骨固定的诊断。虽然在手持传感器的情况下，在0.02秒内测量了镫骨的迁移率，但其刚度曲线与静态测量结果吻合较好。在0.02秒内镫骨活动度的测量不受耳蜗、韧带黏度和手颤的影响。在此之后，将使用微加工技术制作用于临床使用的更小的设备。

It is important to evaluate the stapes mobility in tympanoplasty because it largely affects the degree of the prognostic hearing level. However, the practical objective measurement method of the stapes mobility has not been well established. Within the present study, the sensor was made to measure the displacement and reaction force of the stapes. The stapes mobility of guinea pigs and rabbits with normal and artificially fixed stapes were measured using this sensor, and the objective diagnosis method was discussed. Moreover, an attempt was made to measure the stapes mobility with the sensor held in hand for clinical use. The results could be drawn as follows :1. The reaction force increases linearly in the small displacement region, but nonlinearly in the large displacement region. The stiffnesses of the normal stapes of guinea pigs and rabbits in small displacement region were 16 【minus-plus】 7N/m and 115 【minus-plus】 25N/m, respectively.2. The significant difference was found between the stiffness of the normal and artificially fixed stapes, which as confirmed to be similar to realistic fixation by the CM measurement. These results indicated that this measurement system could be used for diagnosis of the stapes fixation.3. Although the stapes mobility was measured within 0.02 sec with the sensor held in hand, the stiffness curves well agreed with those in static measurement. The measurement of the stapes mobility within 0.02 sec did not be affected by the viscosity of the cochlea and ligament and the hand trembling.After this, a smaller device for clinical use will be made using micromachining technique.