Development of Measurement method of Stapes Mobility

镫骨活动度测量方法的研制

基本信息

  • 批准号:
    10557150
  • 负责人:
  • 金额:
    $ 3.01万
  • 依托单位:
  • 依托单位国家:
    日本
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
  • 财政年份:
    1998
  • 资助国家:
    日本
  • 起止时间:
    1998 至 1999
  • 项目状态:
    已结题

项目摘要

It is important to evaluate the stapes mobility in tympanoplasty because it largely affects the degree of the prognostic hearing level. However, the practical objective measurement method of the stapes mobility has not been well established. Within the present study, the sensor was made to measure the displacement and reaction force of the stapes. The stapes mobility of guinea pigs and rabbits with normal and artificially fixed stapes were measured using this sensor, and the objective diagnosis method was discussed. Moreover, an attempt was made to measure the stapes mobility with the sensor held in hand for clinical use. The results could be drawn as follows :1. The reaction force increases linearly in the small displacement region, but nonlinearly in the large displacement region. The stiffnesses of the normal stapes of guinea pigs and rabbits in small displacement region were 16 【minus-plus】 7N/m and 115 【minus-plus】 25N/m, respectively.2. The significant difference was found between the stiffness of the normal and artificially fixed stapes, which as confirmed to be similar to realistic fixation by the CM measurement. These results indicated that this measurement system could be used for diagnosis of the stapes fixation.3. Although the stapes mobility was measured within 0.02 sec with the sensor held in hand, the stiffness curves well agreed with those in static measurement. The measurement of the stapes mobility within 0.02 sec did not be affected by the viscosity of the cochlea and ligament and the hand trembling.After this, a smaller device for clinical use will be made using micromachining technique.
评估鼓膜成形术中的底座非常重要,因为它在很大程度上影响了预后性听力水平的程度。但是,Stapes迁移率的实际客观测量方法尚未得到很好的确定。在本研究中,制作了传感器以测量stapes的位移和反应力。使用该传感器测量了豚鼠和具有正常和人为固定骨的兔子的缝隙迁移率,并讨论了客观诊断方法。此外,尝试使用手持临床使用的传感器来测量缝合式移动性。结果可以如下绘制:1。反应力在小位移区域中线性增加,但在大型位移区域中非线性地增加。小位移区域中豚鼠和兔子的正常木头的刚度分别为16 [Minus-Plus] 7n/m和115 [Minus-Plus] 25n/m.2。在正常固定的stap骨的刚度和人为固定的stap中发现了显着差异,这与CM测量相似,与CM测量相似。这些结果表明,该测量系统可用于固定木刻的诊断3。尽管固定的传感器握在0.02秒内测量了缝隙迁移率,但刚度曲线与静态测量的刚度曲线非常吻合。在0.02秒内,测量底座迁移率的测量不受耳蜗和韧带的粘度和手颤抖的影响。此后,将使用微加工技术制造较小的临床设备。

项目成果

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KOIKE Takuji其他文献

Development of technology for control of the greenhouse whiteflies using substrate vibration
利用基质振动防治温室粉虱技术的开发
  • DOI:
  • 发表时间:
    2019
  • 期刊:
  • 影响因子:
    0
  • 作者:
    SHIBATA Kengo;TAKANASHI Takuma;KOIKE Takuji;ABE Shouta;HOSOKAWA Akira;ONODERA Ryuichi;ONO Toshifumi;TAYAMA Tsuyoki;OE Takaho;SEKINE Takayuki
  • 通讯作者:
    SEKINE Takayuki

KOIKE Takuji的其他文献

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{{ truncateString('KOIKE Takuji', 18)}}的其他基金

Elucidation of acoustic vibrations and electrical phenomena in the cochlea by a detailed structure model, and feedback to medical care
通过详细的结构模型阐明耳蜗中的声振动和电现象,并向医疗保健提供反馈
  • 批准号:
    17K11317
  • 财政年份:
    2017
  • 资助金额:
    $ 3.01万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Development of cochlear model capable of analyzing mutual interaction between active vibration of the basilar membrane and ionic flow in the cochlea
开发能够分析基底膜主动振动与耳蜗离子流之间相互作用的耳蜗模型
  • 批准号:
    25462631
  • 财政年份:
    2013
  • 资助金额:
    $ 3.01万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Understanding the functional disorders of the auditory organ and development of effective treatment methods
了解听觉器官的功能障碍并开发有效的治疗方法
  • 批准号:
    21592152
  • 财政年份:
    2009
  • 资助金额:
    $ 3.01万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Direct analysis of the variability of the particles located in the lateral membrane of the outer hair cells and transduction mechanism using atomic force microscopy
使用原子力显微镜直接分析位于外毛细胞侧膜的颗粒的变异性和转导机制
  • 批准号:
    12671646
  • 财政年份:
    2000
  • 资助金额:
    $ 3.01万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)

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