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Collection and Investigation into Basic Evolutionary Information by Orrsite Collaboration

Orrsite Collaboration 收集和研究基本进化信息

基本信息

批准号：
16255006
负责人：
TATENO Yoshio
金额：
$ 19.14万
依托单位：
National Institute of Genetics
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (A)
财政年份：
2004
资助国家：
日本
起止时间：
2004 至 2007
项目状态：
已结题

项目摘要

In the term of the present grant from 2004 to 2007 we visited 67 universities and research institutes in 16 countries in total to fulfill our investigation purposes. Since we DDBJ organize the International Nucleotide Sequence Database Collaboration (INSDC) with GenBank in USA and EMBL Bank in Europe, our frequent visits to these two research organizations were crucial and fruitful, resulted in a steep increase in the number of published entries from 35 to 80 million sequences (or 40 to 82 billon bases) in the four years. The published entries include expressed sequences and the whole genome sequence with biological information for many species and thus indispensable for research in biology and related areas. We have also sewed specified databases such as GIB (bacterial genome database), GTOP (protein-structure prediction database) and CIBEX (gene expression database). These databases have been enriched in the contents and the number of users because of various international visits supported by the present grant.Some of the international visits have also contributed to carrying out data annotations of human genes, rice genes and mouse genes. The results of the annotations have been published in their respective databases and journals. For example, we have shown that the total number of genes in the human genome is about 35, 000 that is much larger than previously estimated.Recently, we participated in the international standardization of genome sequence data and published the guidelines for annotating genome sequences of eukaryotes, prokaryotes, viruses, plasmids and others.The outcomes of the international visits have been published in internationally well-known academic journals such as Nature, Nature Biotechnology, Nature Genetics, Science, Proc. Natl. Acad. Sci. USA, Genome Research and Nucleic Acids Research (see the list of publications).

在本次资助期间，从2004年到2007年，我们总共访问了16个国家的67所大学和研究机构，以满足我们的调查目的。自从我们与美国的GenBank和欧洲的EMBL Bank组织了国际核苷酸序列数据库合作(INSDC)以来，我们对这两个研究机构的频繁访问是至关重要的和富有成果的，导致在四年中发表的条目数量从3500万条序列急剧增加到8000万条序列(或40到8200万个碱基)。已发表的条目包括表达序列和包含许多物种的生物学信息的全基因组序列，因此对于生物学和相关领域的研究是不可或缺的。我们还缝制了特定的数据库，如GIB(细菌基因组数据库)、GTOP(蛋白质结构预测数据库)和CIBEX(基因表达数据库)。这些数据库的内容和用户数量因本机构支持的各种国际访问而得到丰富，其中一些国际访问还有助于对人类基因、水稻基因和老鼠基因进行数据注释。注释的结果已在各自的数据库和期刊上发表。例如，我们已经表明，人类基因组中的基因总数约为3.5万个，远远超过此前的估计。最近，我们参与了基因组序列数据的国际标准化工作，发布了真核生物、原核生物、病毒、质粒等基因组序列的注释指南。国际访问的成果已发表在《自然》、《自然生物技术》、《自然遗传学》、《科学》、《PROC》等国际知名学术期刊上。娜塔莉。阿卡德。SCI。美国，基因组研究和核酸研究(见出版物列表)。

项目成果

期刊论文数量（169）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

H-DBAS: alternative splicing database of completely sequenced and manually annotated full-length cDNAs based on H-Invitational.

DOI：
10.1093/nar/gkl854
发表时间：
2007-01
期刊：
NUCLEIC ACIDS RESEARCH
影响因子：
14.9
作者：
Takeda, Jun-ichi;Suzuki, Yutaka;Nakao, Mitsuteru;Kuroda, Tsuyoshi;Sugano, Sumio;Gojobori, Takashi;Imanishi, Tadashi
通讯作者：
Imanishi, Tadashi

The Rice Annotation Project Database (RAP-DB): hub for Oryza sativa ssp. japonica genome information.

DOI：
10.1093/nar/gkj094
发表时间：
2006-01-01
期刊：
NUCLEIC ACIDS RESEARCH
影响因子：
14.9
作者：
Ohyanagi, Hajime;Tanaka, Tsuyoshi;Sakai, Hiroaki;Shigemoto, Yasumasa;Yamaguchi, Kaori;Habara, Takuya;Fujii, Yasuyuki;Antonio, Baltazar A.;Nagamura, Yoshiaki;Imanishi, Tadashi;Ikeo, Kazuho;Itoh, Takeshi;Gojobori, Takashi;Sasaki, Takuji
通讯作者：
Sasaki, Takuji

Tsunami of data:Data resources and utilization.Microbial Genetic Resources and Biodiscovery

数据海啸：数据资源与利用。微生物遗传资源与生物发现