Actin-dependent regulation of synapse function and its role in higher brain fuction
Actin-dependent regulation of synapse function and its role in higher brain fuction
批准号:
19200029
负责人:
SHIRAO Tomoaki
金额:
$22.71万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (A)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2010
中文摘要
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英文摘要
We used primary neuronal cell culture and knockout mice, and showed that the expression levels of spinal actin-binding proteins are related to the synaptic function, such as synaptic strength and plasticity. Then we analyzed the dynamics of spinal accumulation of actin-binding proteins, and found that glutamatergic fibers regulate the accumulation bi-directionally using two subtypes of glutamate receptors.
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Radiosensitivity of newly-generated neurons in the adult brain
成人大脑中新生神经元的放射敏感性
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Nakagami R, Kohda K, Kakegawa W., Kondo T, Kato N, Yuzaki M, Shirao T.]
通讯作者:
Shirao T.
DOI:
10.1038/214054b0
发表时间:
2017-12
期刊:
Nature
影响因子:
64.8
作者:
[Springer Cham;Heidelberg New;Y. London]
通讯作者:
Springer Cham;Heidelberg New;Y. London
嗅球摘出マウス海馬におけるシナプス可塑性関連遺伝子の発現変化
嗅球切除小鼠海马突触可塑性相关基因表达的变化
DOI:
--
发表时间:
2007
期刊:
影响因子:
--
作者:
[竹田 麗子, 長田 千愛, 児島 伸彦, 白尾 智明]
通讯作者:
白尾 智明
Inhibitory effect of 5-HT2A receptor activity on drebrin accumulation in dendritic spines
5-HT2A受体活性对树突棘中drebrin积累的抑制作用
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Buckley MJ, Mansouri F, Mahboubi M, Kwok SC, Tanaka K, 六本木T麗子]
通讯作者:
六本木T麗子
気になる脳部位海馬のCA2領域
海马体 CA2 区域,一个值得关注的大脑区域
DOI:
--
发表时间:
2009
期刊:
分子精神医学 9
影响因子:
--
作者:
[Setsuie, R., Sakurai, M., Sakaguchi, Y., Wada, K., 柚崎通介, 関野祐子]
通讯作者:
関野祐子
共 110 条
Mapping of the developmental stages of neurons in the brain using the radiosensitivity as an index.
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批准号:22650076
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.12万
-
财政年份:2010
-
负责人:SHIRAO Tomoaki
-
依托单位:
Role of actin cytoskeleton in the axonal growthcone during brain development
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批准号:16300117
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.47万
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财政年份:2004
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负责人:SHIRAO Tomoaki
-
依托单位:
Regulation of synaptic actin reorganization by signal transmission with drebrin family
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批准号:12480236
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.54万
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财政年份:2000
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负责人:SHIRAO Tomoaki
-
依托单位:
Distribution of drebrin containing synapses in the brain
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批准号:10044237
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项目类别:Grant-in-Aid for international Scientific Research
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资助金额:$1.34万
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财政年份:1998
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负责人:SHIRAO Tomoaki
-
依托单位:
Development and Aging of Neuronal Synapse
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批准号:09480219
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.38万
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财政年份:1997
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负责人:SHIRAO Tomoaki
-
依托单位:
Molecular Mechanism in Regulation of Neuronal Dendritic Morphology
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批准号:07458203
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$4.8万
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财政年份:1995
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负责人:SHIRAO Tomoaki
-
依托单位:
海外基金